ESR1 and UBE2I

Number of citations of the paper that reports this interaction (PubMedID 15961505)
0

Data Source:
BioGRID (enzymatic study)
HPRD (two hybrid)

		ESR1	UBE2I
Description		estrogen receptor 1	ubiquitin conjugating enzyme E2 I
Image
GO Annotations	Cellular Component	Chromatin Euchromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Protein-containing Complex	Synaptonemal Complex Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Cytosol Nuclear Body PML Body Perinuclear Region Of Cytoplasm Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Presynaptic Cytosol Postsynaptic Cytosol SUMO Ligase Complex Transferase Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific TFIIB-class Transcription Factor Binding Transcription Coregulator Binding Transcription Corepressor Binding Transcription Coactivator Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Nuclear Steroid Receptor Activity Nuclear Receptor Activity Steroid Binding Protein Binding Calmodulin Binding Beta-catenin Binding Zinc Ion Binding Lipid Binding TBP-class Protein Binding Enzyme Binding Protein Kinase Binding Nitric-oxide Synthase Regulator Activity Nuclear Estrogen Receptor Activity Nuclear Estrogen Receptor Binding Estrogen Response Element Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding ATPase Binding 14-3-3 Protein Binding Sequence-specific Double-stranded DNA Binding	Nucleotide Binding Transcription Coregulator Binding RNA Binding Protein Binding ATP Binding Transcription Factor Binding Transferase Activity SUMO Transferase Activity Enzyme Binding HLH Domain Binding Small Protein Activating Enzyme Binding SUMO Conjugating Enzyme Activity RING-like Zinc Finger Domain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Antral Ovarian Follicle Growth Epithelial Cell Development Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Signal Transduction Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Androgen Metabolic Process Male Gonad Development Negative Regulation Of Gene Expression Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Estrogen Receptor Signaling Pathway Response To Estradiol Regulation Of Toll-like Receptor Signaling Pathway Negative Regulation Of Smooth Muscle Cell Apoptotic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction Steroid Hormone Receptor Signaling Pathway Negative Regulation Of DNA-binding Transcription Factor Activity Response To Estrogen Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Fibroblast Proliferation Positive Regulation Of Fibroblast Proliferation Stem Cell Differentiation Regulation Of Inflammatory Response Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of DNA-binding Transcription Factor Activity RNA Polymerase II Preinitiation Complex Assembly Uterus Development Vagina Development Prostate Epithelial Cord Elongation Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Regulation Of Branching Involved In Prostate Gland Morphogenesis Mammary Gland Branching Involved In Pregnancy Mammary Gland Alveolus Development Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Protein Localization To Chromatin Cellular Response To Estrogen Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Oxygen-containing Compound Negative Regulation Of MiRNA Transcription Regulation Of Epithelial Cell Apoptotic Process	Negative Regulation Of Transcription By RNA Polymerase II Ubiquitin-dependent Protein Catabolic Process Chromosome Segregation Mitotic Nuclear Membrane Reassembly Protein Sumoylation Positive Regulation Of Cell Migration Protein Modification Process Positive Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of DNA-templated Transcription Modulation Of Chemical Synaptic Transmission Nuclear Export Cell Division
Pathways		Nuclear signaling by ERBB4 PIP3 activates AKT signaling Constitutive Signaling by Aberrant PI3K in Cancer Nuclear Receptor transcription pathway SUMOylation of intracellular receptors Ovarian tumor domain proteases PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling TFAP2 (AP-2) family regulates transcription of growth factors and their receptors RUNX1 regulates estrogen receptor mediated transcription ESR-mediated signaling RUNX1 regulates transcription of genes involved in WNT signaling Regulation of RUNX2 expression and activity Regulation of RUNX2 expression and activity Extra-nuclear estrogen signaling Estrogen-dependent gene expression Mitochondrial unfolded protein response (UPRmt) Developmental Lineage of Mammary Gland Luminal Epithelial Cells Developmental Lineage of Mammary Gland Alveolar Cells	Meiotic synapsis Vitamin D (calciferol) metabolism SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMOylation of DNA damage response and repair proteins SUMOylation of transcription factors SUMOylation of transcription factors SUMOylation of ubiquitinylation proteins SUMOylation of transcription cofactors SUMOylation of transcription cofactors SUMOylation of SUMOylation proteins SUMOylation of intracellular receptors SUMOylation of intracellular receptors SUMOylation of chromatin organization proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins SUMOylation of DNA methylation proteins SUMOylation of DNA methylation proteins SUMOylation of immune response proteins Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Processing of DNA double-strand break ends Formation of Incision Complex in GG-NER Negative regulation of activity of TFAP2 (AP-2) family transcription factors Negative regulation of activity of TFAP2 (AP-2) family transcription factors Postmitotic nuclear pore complex (NPC) reformation Maturation of nucleoprotein Maturation of nucleoprotein SARS-CoV-1 targets host intracellular signalling and regulatory pathways SUMOylation of nuclear envelope proteins PKR-mediated signaling Regulation of endogenous retroelements by KRAB-ZFP proteins Transcriptional and post-translational regulation of MITF-M expression and activity
Drugs		Diethylstilbestrol Chlorotrianisene Conjugated estrogens Desogestrel Levonorgestrel Progesterone Lindane Raloxifene Toremifene Medroxyprogesterone acetate Testosterone Mitotane Estrone Tamoxifen Hexachlorophene Estradiol Ethynodiol diacetate Dobutamine Clomifene Dienestrol Fulvestrant Norgestimate Ethinylestradiol Melatonin Trilostane Naloxone Fluoxymesterone Estramustine Mestranol Danazol Oxybenzone Allylestrenol Zinc Genistein Prasterone Benzophenone Equilin Compound 19 Resveratrol Compound 18 Phthalic Acid Pyrazole Stanolone Naringenin Compound 4-D 1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol Quercetin Afimoxifene 2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol Estriol Estrone sulfate Quinestrol Phenolphthalein Permethrin Ospemifene AP1081 Custirsen NP-50301 CHF 4227 TAS-108 Lasofoxifene Arzoxifene Elacestrant Bazedoxifene Methyltestosterone beta-Naphthoflavone 17-METHYL-17-ALPHA-DIHYDROEQUILENIN din-6-yl)phenol [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL 4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL (2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL (9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL 3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL Hexestrol dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate Erteberel N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL 4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol 4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine 4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL 2-(4-hydroxyphenyl)benzo[b]thiophen-6-ol Tibolone Eugenol Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, B Polyestradiol phosphate Norethynodrel Octocrylene Homosalate Enzacamene Zeranol Ractopamine Gestrinone Estetrol Propyl Gallate Ormeloxifene 2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol Testosterone cypionate Testosterone enanthate Stanolone acetate Estradiol acetate Estradiol benzoate Estradiol cypionate Estradiol dienanthate Estradiol valerate Zinc acetate Zinc chloride Zinc sulfate, unspecified form Estriol tripropionate Fluoroestradiol F-18
Diseases
GWAS		Age at first birth ( 27089180 34211149 27798627) Age at first sexual intercourse ( 27089180 34211149) Alcohol dependence ( 19581569) Anxiety ( 31906708) Appendicular lean mass ( 33097823) Birth weight ( 31043758 27680694) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Bone mineral density ( 23437003) Bone mineral density (hip) ( 18445777 19801982 19079262) Bone mineral density (spine) ( 30172743 27424934 18445777 26911590 19079262 19801982) Bone mineral density (Ward's triangle area) ( 27397699) Bone properties (heel) ( 24430505) Bone ultrasound measurement (broadband ultrasound attenuation) ( 28472463) Bone ultrasound measurement (velocity of sound) ( 28472463) BRCA1/2-negative high-risk breast cancer ( 30323354) Breast cancer ( 21263130 22383897 29059683 25327703 31757997 27117709 23535729 23535733 20453838 19219042) Breast cancer (estrogen-receptor negative) ( 27117709 29058716) Breast cancer (estrogen-receptor negative, progesterone-receptor negative, and human epidermal growth factor-receptor negative) ( 24325915) Breast Cancer in BRCA1 mutation carriers ( 29058716) Breast size ( 29855537 27182965 22747683) Chronic myeloid leukemia ( 21540461) Developmental language disorder ( 27016271) Diastolic blood pressure ( 30578418) Endometriosis ( 28537267) Fractures ( 30158200) Haemorrhoidal disease ( 33888516) Heel bone mineral density ( 31453325 28869591 30598549 30048462) Heel bone mineral density variance ( 31453325) Height ( 25282103 33713608 28552196 31562340 20881960 23563607) Hip circumference adjusted for BMI ( 34021172) Interleukin-10 levels in non-alcoholic fatty liver disease x mastiha supplementation interaction ( 34025683) Mammographic density (dense area) ( 25342443) Menarche (age at onset) ( 25231870) Obesity-related traits ( 23251661) Offspring birth weight ( 31043758) Pulse pressure ( 28135244 30578418 27841878) Resistance to Mycobacterium tuberculosis in HIV-positive individuals measured by a negative tuberculin skin test (dichotomous) ( 28628665) Smoking status (current vs former) ( 27393504) Sudden cardiac arrest ( 21658281) Systolic blood pressure ( 30578418 27841878) Uterine fibroids ( 31649266) Waist circumference adjusted for body mass index ( 28552196) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Western dietary pattern ( 28644415)	Appendicular lean mass ( 33097823) Idiopathic dilated cardiomyopathy ( 29495422) Monocyte percentage of white cells ( 32888494) Pulse pressure ( 30224653 30578418) Refractive error ( 32231278) Systolic blood pressure ( 30578418) White blood cell count ( 32888494)
Interacting Genes		370 interacting genes: ACTN4 AHR AKAP13 AKT1 AKT2 ALYREF ANGPTL4 ANP32B AR ARHGEF15 ARID1A ARNT ATAD2 BAG1 BAP1 BARD1 BCAR1 BCAS2 BDNF BRCA1 CALM1 CALM2 CALM3 CAV1 CBLL1 CCND1 CCNH CCNT1 CCT2 CDC25B CDK2 CDK7 CDK8 CDKN1A CEBPA CEBPB CFL1 CHD9 CHUK CITED1 COPS5 CREBBP CSNK2B CSRP1 CTNNB1 CUEDC2 CUL4B CXCL1 DAP3 DARS1 DBN1 DDX1 DDX17 DDX3X DDX5 DDX54 DNMT3L DNTTIP2 DUT EEF2 EGFR EHMT2 EIF2S2 EIF3I EIF4A3 EP300 EPAS1 EPSTI1 ERBB2 ESR2 ESRRA FARSA FBH1 FHL2 FKBP4 FKBP5 FLII FOXK2 FOXO1 FOXO3 FOXO4 FUBP1 GADD45B GADD45G GLCE GNAI1 GRB2 GREB1 GRIP1 GRWD1 GTF2B GTF2H1 H2AC20 H2BC10 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H3-3A H3-3B HBP1 HDAC3 HDAC4 HDAC5 HDAC9 HDLBP HEXIM1 HNF4A HNRNPA1 HNRNPA2B1 HNRNPC HNRNPD HSP90AA1 HSP90AB1 HSP90B1 HSPA4 HSPA8 HSPB1 IGF1R ILF3 ING1 ISL1 ITGB3BP JUN JUNB JUND KARS1 KAT5 KDM5A KIF1A KLF5 KLK5 KLK9 KMT2D KMT5B KRT10 KRT18 KRT19 KRT8 LARS1 LCK LCOR LDB1 LINC00312 LRIF1 MAPK1 MAPK14 MAPK3 MARS1 MDM2 MED1 MED10 MED12 MED13 MED14 MED16 MED17 MED20 MED21 MED23 MED24 MED27 MED6 MED7 MEN1 MGMT MINDY1 MKNK2 MMS19 MNAT1 MPG MSH2 MTA1 MTA2 MTCH2 MTHFD1 MTOR MUC1 MVP MYBBP1A MYH6 NAP1L4 NCL NCOA1 NCOA2 NCOA3 NCOA4 NCOA6 NCOA7 NCOR1 NCOR2 NELFB NFKB1 NONO NPM1 NPPA NR0B1 NR0B2 NR1H4 NR2C1 NR2C2 NR2F1 NR2F6 NRIP1 NSD1 NSD2 NSD3 NSF NUDT21 OTUB1 P4HB PA2G4 PAGR1 PAK1 PAK6 PBXIP1 PDIA3 PELP1 PGC PGR PHB1 PHB2 PIAS1 PIAS2 PIAS3 PIK3R1 PIK3R3 PNRC2 POLR1B POLR2A POLR2D POU2F1 POU2F2 POU4F1 POU4F2 PPARGC1A PPARGC1B PPIB PPID PPP1CA PPP2R1A PQBP1 PRDM2 PRKACA PRKCSH PRMT1 PRMT2 PRPF19 PRPF6 PSMC3IP PSMC5 PSMD1 PSPC1 PTEN PTGES3 PTMA PTPN1 PTPN6 RAC3 RACK1 RANBP9 RARA RBBP4 RBBP7 RBFOX2 RBM23 RBM39 RELA REXO4 RFX4 RGS3 RLIM RNF111 RNF14 RNF4 RPL9 RPS6KA1 RPS6KA3 RTCB RXRA SAFB SAFB2 SARNP SARS2 SEPTIN2 SEPTIN8 SERBP1 SERPINB5 SET SETD7 SFMBT2 SFPQ SHC1 SHMT2 SKIL SKP2 SLC30A9 SMAD2 SMAD3 SMAD4 SMARCA2 SMARCA4 SMARCD1 SMARCD3 SMARCE1 SMC1A SMC3 SMYD2 SND1 SNX6 SOS1 SP1 SP3 SRA1 SRC SREBF1 STAT3 STAT5A STRN STUB1 SUV39H1 SVIL SYNCRIP TADA3 TAF10 TAF1A TAF1B TAF2 TAP1 TBP TCERG1 TCF20 TDG THRA THRB TNFRSF14 TOPBP1 TP53 TRAM1 TRIM24 TRIM25 TRIM28 TRIM59 TRIM8 TRIP4 TRRAP TSC2 TUBA1B TUBA1C TUBB TXNRD1 UBE2I UBE3A UBE4B UBR5 UIMC1 USF1 VAV3 VCP WBP2 WIPI1 XAF1 XBP1 YARS1 YWHAH YWHAQ ZBTB16 ZBTB17 ZNF398	486 interacting genes: - ACTB ADAR ADARB1 ADD3 AGR2 AGTRAP AKAP17A ANAPC4 ANXA1 APEX1 APP AR ARHGDIA ARK2N ARL13B ARL6IP1 ARNT ARRB2 ATF2 ATF3 ATF7IP ATXN1 AURKA AURKB BANP BCAM BCL11A BCL2L1 BEND5 BHLHE40 BIRC3 BIRC7 BLM BLMH BMAL1 BMI1 BTBD3 CALU CAMK2D CAMK2G CAMSAP2 CARD9 CARM1 CASP2 CASP8AP2 CBLC CBS CBX4 CCDC6 CD2AP CDC37 CDCA8 CDH4 CDR2L CEBPA CEBPD CEBPE CENPX CFL2 CFTR CHD3 CHD4 CHFR CHMP1A CHMP4B CHUK CLDN2 CLK2 COG1 CORO2A CREB1 CREBBP CREBL2 CREM CSGALNACT2 CSK CSNK2B CTBP2 CTNNA1 CYP4F2 DACH1 DAXX DCTD DDX21 DDX24 DDX39A DDX39B DDX5 DES DHX9 DMC1 DNM1 DNMT3A DNMT3B DPPA2 DPYSL2 DRG1 DTX3L DZIP3 EDARADD EDF1 EGR2 EIF2AK2 EIF2B1 EIF5A ELK1 EP300 ERCC6 ESR1 ETS1 ETV1 ETV6 EXO1 EXOSC9 FADD FAF1 FAM118A FANCM FAS FATE1 FHIT FHL3 FLI1 FMR1 FOS FOXL2 FOXM1 GCM1 GIPC2 GLUL GMCL1 GMCL2 GMEB1 GMEB2 GOLGA1 GOLGA2 GOLGB1 GRIP1 GTF2I H4C16 HABP4 HDAC1 HDAC4 HDAC5 HDAC7 HGS HIC1 HIF1A HIPK1 HIPK2 HIPK3 HIRA HMBOX1 HMGB1 HMGN2 HMGXB4 HNF4A HNRNPC HNRNPCL1 HNRNPD HNRNPK HNRNPLL HNRNPM HNRNPU HSF1 HSF2 HSF2BP IKBKG IKZF1 IKZF3 IKZF5 IMPDH1 IPO13 IQGAP1 JUN JUNB KAT2A KAT6B KCNA5 KCNK1 KCTD1 KDM1A KHSRP KLF3 KLF5 KLHL12 KLHL2 KMT5A KRT19 KRTAP5-2 KRTAP5-4 KRTAP5-9 KTN1 LATS1 LCE1D LCE1F LCE2C LCE3B LCE5A LMNA LMNB1 LMO2 LNX2 LONRF1 LRSAM1 MALL MAP2K1 MAP3K1 MAP3K5 MAPK1IP1L MARCHF5 MAT2A MATR3 MBD4 MDM2 MECOM MED7 MEF2C MGRN1 MIPOL1 MITF MKRN3 MLX MORC3 MRTFA MTA1 MYB MYBBP1A MYH9 NACC1 NAF1 NAT10 NCOR2 NFE2 NFKBIA NHP2 NIN NMI NOL6 NONO NOP2 NOP56 NOP58 NOX5 NR1D2 NR1H2 NR1H3 NR1I2 NR3C1 NR3C2 NR5A1 NR5A2 NRIP1 NSD3 NUDCD3 NVL PAICS PARK7 PARP1 PAX5 PCNA PDLIM7 PDPK1 PDZK1 PELI1 PEX10 PHC1 PIAS1 PIAS2 PIAS3 PIAS4 PIM1 PLAAT4 PLAGL1 PLK1 PML POLR1H POU1F1 POU2F1 PPARA PPARG PPARGC1A PPCDC PPM1J PRKAA2 PRKDC PROP1 PRPF40A PRPF8 PRPSAP1 PSMC3 PSMC6 PSME3 PTEN PUF60 RABAC1 RAD18 RAD51 RAD52 RAD54B RAD54L2 RANBP2 RANGAP1 RB1 RBBP5 RBBP6 RBBP8 RBM14 RBM25 RC3H2 RCBTB2 RFPL3 RHOB RHOXF2 RIPK2 RNF10 RNF111 RNF115 RNF128 RNF133 RNF144B RNF151 RNF185 RNF4 RNF40 ROCK2 RORB RPL11 RPL7 RPL8 RPRD1B RPS3A RPS6KA6 RUSF1 RWDD3 RXRA SAE1 SALL1 SART1 SATB1 SCNN1A SEMA6A SEPTIN1 SETBP1 SETDB1 SETX SFPQ SH3KBP1 SIAH1 SIAH2 SIRT1 SKIL SLC2A1 SLC2A4 SLX4 SMAD4 SNAI2 SND1 SNIP1 SNRNP200 SOCS6 SOX10 SOX4 SOX5 SOX9 SP100 SP3 SPECC1L SPOP SREBF1 SREBF2 SRF SRSF4 SSRP1 STAT1 STIP1 STMN2 STX1A STX1B STX2 SUMO1 SUMO1P1 SUMO2 SUMO3 SUPT7L SUZ12 SYMPK TAB2 TAF1 TAF10 TAF12 TAF5 TBL1X TBL1XR1 TBP TCERG1 TCF3 TCF4 TDG TDP2 TERF2 TFAP2A TFAP2B TFAP2C TFCP2 TFG THAP1 THRA THRB TIGD3 TLK2 TNFRSF1A TOP1 TOP2A TOP2B TOPORS TP53 TP63 TP73 TRAF2 TRAF3 TRAF4 TRAF6 TRIM21 TRIM23 TRIM24 TRIM27 TRIM28 TRIM29 TRIM38 TRIM41 TRIM54 TRIM63 TRIM72 TRIP13 TRPS1 TSHZ2 TSN TSNAX TTN TXLNB UBA2 UBE2K UBQLN1 UBQLN2 UBXN1 UCHL1 UNC119 USP25 USP36 VENTX VEZF1 VHL WNK1 WT1 WWP2 XBP1 XIAP XRCC1 XRCC5 YY1 ZBED1 ZBTB1 ZBTB16 ZBTB2 ZBTB26 ZBTB7A ZBTB8A ZBTB9 ZC3H10 ZCCHC12 ZCCHC7 ZEB2 ZG16 ZIC1 ZMYM2 ZNF106 ZNF24 ZNF408 ZNF446 ZNF451 ZNF618 ZNF646 ZNF837 ZNRD2
Entrez ID		2099	7329
HPRD ID		00589	09045
Ensembl ID		ENSG00000091831	ENSG00000103275
Uniprot IDs		A0A125SXW3 A8KAF4 G4XH65 H0Y4W6 P03372 Q9UBT1	A8K503 P63279 Q7KZS0
PDB IDs		1A52 1ERE 1ERR 1G50 1GWQ 1GWR 1HCP 1HCQ 1L2I 1PCG 1QKT 1QKU 1R5K 1SJ0 1UOM 1X7E 1X7R 1XP1 1XP6 1XP9 1XPC 1XQC 1YIM 1YIN 1ZKY 2AYR 2B1V 2B1Z 2B23 2BJ4 2FAI 2G44 2G5O 2I0J 2IOG 2IOK 2JF9 2JFA 2LLO 2LLQ 2OCF 2OUZ 2P15 2POG 2Q6J 2Q70 2QA6 2QA8 2QAB 2QE4 2QGT 2QGW 2QH6 2QR9 2QSE 2QXM 2QXS 2QZO 2R6W 2R6Y 2YAT 2YJA 3CBM 3CBO 3CBP 3DT3 3ERD 3ERT 3HLV 3HM1 3L03 3OS8 3OS9 3OSA 3Q95 3UU7 3UUA 3UUC 3UUD 4AA6 4DMA 4IU7 4IUI 4IV2 4IV4 4IVW 4IVY 4IW6 4IW8 4IWC 4IWF 4JC3 4JDD 4MG5 4MG6 4MG7 4MG8 4MG9 4MGA 4MGB 4MGC 4MGD 4O6F 4PP6 4PPP 4PPS 4PXM 4Q13 4Q50 4TUZ 4TV1 4XI3 4ZN7 4ZN9 4ZNH 4ZNS 4ZNT 4ZNU 4ZNV 4ZNW 5AAU 5AAV 5ACC 5AK2 5DI7 5DID 5DIE 5DIG 5DK9 5DKB 5DKE 5DKG 5DKS 5DL4 5DLR 5DMC 5DMF 5DP0 5DRJ 5DRM 5DTV 5DU5 5DUE 5DUG 5DUH 5DVS 5DVV 5DWE 5DWG 5DWI 5DWJ 5DX3 5DXB 5DXE 5DXG 5DXK 5DXM 5DXP 5DXQ 5DXR 5DY8 5DYB 5DYD 5DZ0 5DZ1 5DZ3 5DZH 5DZI 5E0W 5E0X 5E14 5E15 5E19 5E1C 5EGV 5EHJ 5EI1 5EIT 5FQP 5FQR 5FQS 5FQT 5FQV 5GS4 5GTR 5HYR 5JMM 5KCC 5KCD 5KCE 5KCF 5KCT 5KCU 5KCW 5KD9 5KR9 5KRA 5KRC 5KRF 5KRH 5KRI 5KRJ 5KRK 5KRL 5KRM 5KRO 5N10 5T0X 5T1Z 5T92 5T97 5TLD 5TLF 5TLG 5TLL 5TLM 5TLO 5TLP 5TLT 5TLU 5TLV 5TLX 5TLY 5TM1 5TM2 5TM3 5TM4 5TM5 5TM6 5TM7 5TM8 5TM9 5TML 5TMM 5TMO 5TMQ 5TMR 5TMS 5TMT 5TMU 5TMV 5TMW 5TMZ 5TN1 5TN3 5TN4 5TN5 5TN6 5TN7 5TN8 5TN9 5TNB 5U2B 5U2D 5UFW 5UFX 5W9C 5W9D 5WGD 5WGQ 6B0F 6C42 6CBZ 6CHW 6CHZ 6CZN 6D0F 6DF6 6DFN 6HHP 6HKB 6HKF 6HMU 6IAR 6OWC 6PET 6PFM 6PIT 6PSJ 6SBO 6SQ0 6SUO 6TJM 6TL3 6V87 6V8T 6VGH 6VJD 6VPF 6WOK 6ZOQ 6ZOR 6ZOS 7B9M 7B9R 7B9T 7BA3 7BA5 7BA6 7BA7 7BA8 7BA9 7BAA 7BAB 7JHD 7KBS 7MSA 7N9O 7NDO 7NEL 7NFB 7NFW 7NIZ 7OPW 7OQ7 7OQ8 7PWT 7PWZ 7QVJ 7QVL 7R62 7RKE 7RNM 7RRX 7RRY 7RRZ 7RS0 7RS1 7RS2 7RS3 7RS4 7RS7 7RS8 7RS9 7SFO 7T2X 7TE7 7UJ7 7UJ8 7UJC 7UJF 7UJM 7UJO 7UJW 7UJY 7WNV 7Y8F 7Y8G 7YMK 8AFN 8AI0 8ALR 8ALT 8ALV 8ALW 8AM7 8ANF 8AOY 8APS 8AQ1 8AQC 8AQE 8AQZ 8AR4 8AR5 8ARG 8ARO 8ARQ 8ARR 8ARW 8ARX 8ARY 8ARZ 8AS1 8AT9 8ATP 8AU2 8AUS 8AUY 8AV3 8AV4 8AV7 8AV8 8AWG 8AXE 8AXU 8AZE 8B39 8BWJ 8BWX 8BWZ 8BX0 8BX3 8BX4 8BXI 8BXM 8BXN 8BXO 8BXQ 8BXS 8BY9 8BYB 8BYC 8BYD 8BYE 8BYF 8BYG 8BYO 8BYY 8BYZ 8BZ0 8BZ9 8BZA 8BZB 8BZC 8BZD 8BZE 8BZF 8BZG 8BZH 8BZT 8BZW 8C04 8C0K 8C0L 8C42 8C4F 8C4G 8DU6 8DU8 8DU9 8DUB 8DUC 8DUD 8DUG 8DUH 8DUI 8DUK 8DUS 8DV5 8DV7 8DV8 8DVB 8EV1 8EV2 8VYT 8VYX 8VZ0 8VZ1 8VZP 8VZQ 8W03 8W07 9BPX 9BQE 9BU1	1A3S 1KPS 1Z5S 2GRN 2GRO 2GRP 2GRQ 2GRR 2O25 2PE6 2PX9 2XWU 3A4S 3UIN 3UIO 3UIP 4W5V 4Y1L 5D2M 5F6D 5F6E 5F6U 5F6V 5F6W 5F6X 5F6Y 5FQ2 6SYF 8ODR 9B62
Enriched GO Terms of Interacting Partners?		Nucleoplasm Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Binding Transcription Coactivator Activity Nucleic Acid Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process Chromatin Intracellular Signal Transduction Nucleobase-containing Compound Metabolic Process Intracellular Receptor Signaling Pathway Negative Regulation Of Transcription By RNA Polymerase II Nuclear Receptor Binding Nuclear Receptor-mediated Signaling Pathway Macromolecule Metabolic Process RNA Metabolic Process DNA-templated Transcription Transcription Coregulator Activity Chromatin Organization Chromatin Remodeling Hormone-mediated Signaling Pathway Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway DNA Binding Nuclear Estrogen Receptor Binding	Nucleus Nucleoplasm Identical Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process DNA Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Macromolecule Metabolic Process Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding PML Body RNA Polymerase II-specific DNA-binding Transcription Factor Binding Nucleic Acid Metabolic Process Sequence-specific DNA Binding DNA-binding Transcription Factor Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Cellular Response To Stress DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-templated Transcription Nucleobase-containing Compound Metabolic Process Protein Modification By Small Protein Conjugation Transcription Cis-regulatory Region Binding Zinc Ion Binding
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