AKT1 and GRB10

  • Number of citations of the paper that reports this interaction (PMID 11809791)
  • 10
  • Data Source:
  • HPRD (in vivo)

AKT1

GRB10

Gene Name v-akt murine thymoma viral oncogene homolog 1 growth factor receptor-bound protein 10
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (childhood) ( 23512250)
  • Bone mineral density ( 22504420)
  • Fasting glucose-related traits (interaction with BMI) ( 22581228)
  • Systemic sclerosis ( 21779181)
Protein-Protein Interactions 191 interactors: ACAP1 AHNAK AKT1S1 AKT2 AKTIP ALYREF APLP2 APOH APP APPL1 AR ARFIP2 ARHGAP29 ARHGAP32 ATXN1 BAD BCL10 BCL2L1 BCL2L11 BPGM BRAF BRCA1 CAMKK1 CARHSP1 CASP3 CASP9 CCDC88A CDKN1A CDKN1B CDKN1C CHEK1 CHN2 CHUK CLIP3 CLK2 CREB1 CREBBP CSNK2A1 CTNNB1 CYLD DAB2IP DCTN1 DLC1 DNAJB1 DNMT1 EEF1G EIF4EBP1 EP300 ESR1 ESR2 EZH2 FANCA FOXO1 FOXO3 FOXO4 GAB2 GATA1 GATA2 GRB10 GSK3A GSK3B HIST2H2BE HMOX1 HSP90AA1 HSP90AB1 HSPB1 HTT IKBKB ILK IMPDH2 IRAK1 IRS1 ITGB3 ITPR1 ITPR3 JADE1 KAT2B KAT6A KRT10 KTN1 LRRK2 MAP2K4 MAP3K11 MAP3K5 MAP3K8 MAPK14 MAPK8IP1 MAPKAPK2 MAPT MDM2 MDM4 METTL1 MS4A2 MST1R MTCP1 MTOR MUL1 MXD1 NCOA4 NCOR2 NF2 NOS3 NOTCH1 NR4A1 PAK1 PAK6 PDE3B PDK2 PDPK1 PEA15 PFKFB1 PFKFB2 PHB2 PI4K2B PIAS1 PIAS2 PIK3R1 PKN2 PLCG1 PLEKHO1 PLXNA1 PPARGC1B PPL PPM1A PPP1CA PPP2CA PPP2R1A PPP2R4 PRG2 PRKCQ PRKCZ PRKDC PTEN PTPN1 RAB3D RAC1 RAF1 RARA RGCC RHEBL1 RICTOR RNF11 RNF115 RPS6KB1 RQCD1 S1PR1 SETDB1 SH2B2 SH3RF1 SIRT1 SIRT6 SKI SKP2 SMAD2 SMAD3 SMAD4 SMAD7 SMARCB1 SMARCC1 SNCA SORBS2 SORBS3 SRC STAT1 STK3 STK4 TBC1D4 TCL1A TCL1B TCL6 TERF2IP TERT THEM4 TNFSF11 TOPBP1 TRIB3 TSC1 TSC2 TTC3 USP4 UXS1 VEGFA VIM WNK1 WNK4 XIAP YAP1 YBX1 YWHAZ ZFP36L1 ZHX1 30 interactors: ABL1 AKT1 APP BCR DOK1 EGFR ELK1 EPHB1 FYN GHR GIGYF1 GIGYF2 IGF1R INSR IRS1 JAK2 KDR KIT MAP2K1 MAP3K14 MAPK1 MEGF10 NEDD4 NOA1 PDGFRB RAF1 RET RQCD1 SRC ZDHHC17
Entrez ID 207 2887
HPRD ID 01261 03312
Ensembl ID ENSG00000142208 ENSG00000106070
Uniprot IDs B0LPE5 B3KVH4 P31749 Q13322
PDB IDs 1H10 1UNP 1UNQ 1UNR 2UVM 2UZR 2UZS 3CQU 3CQW 3MV5 3MVH 3O96 3OCB 3OW4 3QKK 3QKL 3QKM 4EJN 4EKK 4EKL 4GV1 1NRV 3HK0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
advance  catenin  contributes  decreasing  deregulation  doi  dramatically  foxo1  glioma  gliomas  implicate  inducing  insights  introduction  invasion  january  micrornas  mir  mirnas  onc  oncogene  online  phosphorylated  publication  silencing  suppressed  tissues  tumorigenesis  unfavorable 
becomes  carries  cytokine  driven  effector  emerging  exert  fashion  fos  grbir  homology  hybrid  insights  interacting  looked  member  nonreceptor  obscure  phosphorylated  pleckstrin  profoundly  ptks  subfamily  subset  suppresses  syk  tec  tips  turned 
Tagcloud (Difference) ?
advance  catenin  contributes  decreasing  deregulation  doi  dramatically  foxo1  glioma  gliomas  implicate  inducing  introduction  invasion  january  micrornas  mir  mirnas  onc  oncogene  online  publication  silencing  suppressed  tissues  tumorigenesis  unfavorable 
becomes  carries  cytokine  driven  effector  emerging  exert  fashion  fos  grbir  homology  hybrid  interacting  looked  member  nonreceptor  obscure  pleckstrin  profoundly  ptks  subfamily  subset  suppresses  syk  tec  tips  turned 
Tagcloud (Intersection) ?
insights  phosphorylated