AKT1 and CYLD

  • Number of citations of the paper that reports this interaction (PMID 23300340)
  • 3
  • Data Source:
  • BioGRID (enzymatic study, affinity chromatography technology)

AKT1

CYLD

Gene Name v-akt murine thymoma viral oncogene homolog 1 cylindromatosis (turban tumor syndrome)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 191 interactors: ACAP1 AHNAK AKT1S1 AKT2 AKTIP ALYREF APLP2 APOH APP APPL1 AR ARFIP2 ARHGAP29 ARHGAP32 ATXN1 BAD BCL10 BCL2L1 BCL2L11 BPGM BRAF BRCA1 CAMKK1 CARHSP1 CASP3 CASP9 CCDC88A CDKN1A CDKN1B CDKN1C CHEK1 CHN2 CHUK CLIP3 CLK2 CREB1 CREBBP CSNK2A1 CTNNB1 CYLD DAB2IP DCTN1 DLC1 DNAJB1 DNMT1 EEF1G EIF4EBP1 EP300 ESR1 ESR2 EZH2 FANCA FOXO1 FOXO3 FOXO4 GAB2 GATA1 GATA2 GRB10 GSK3A GSK3B HIST2H2BE HMOX1 HSP90AA1 HSP90AB1 HSPB1 HTT IKBKB ILK IMPDH2 IRAK1 IRS1 ITGB3 ITPR1 ITPR3 JADE1 KAT2B KAT6A KRT10 KTN1 LRRK2 MAP2K4 MAP3K11 MAP3K5 MAP3K8 MAPK14 MAPK8IP1 MAPKAPK2 MAPT MDM2 MDM4 METTL1 MS4A2 MST1R MTCP1 MTOR MUL1 MXD1 NCOA4 NCOR2 NF2 NOS3 NOTCH1 NR4A1 PAK1 PAK6 PDE3B PDK2 PDPK1 PEA15 PFKFB1 PFKFB2 PHB2 PI4K2B PIAS1 PIAS2 PIK3R1 PKN2 PLCG1 PLEKHO1 PLXNA1 PPARGC1B PPL PPM1A PPP1CA PPP2CA PPP2R1A PPP2R4 PRG2 PRKCQ PRKCZ PRKDC PTEN PTPN1 RAB3D RAC1 RAF1 RARA RGCC RHEBL1 RICTOR RNF11 RNF115 RPS6KB1 RQCD1 S1PR1 SETDB1 SH2B2 SH3RF1 SIRT1 SIRT6 SKI SKP2 SMAD2 SMAD3 SMAD4 SMAD7 SMARCB1 SMARCC1 SNCA SORBS2 SORBS3 SRC STAT1 STK3 STK4 TBC1D4 TCL1A TCL1B TCL6 TERF2IP TERT THEM4 TNFSF11 TOPBP1 TRIB3 TSC1 TSC2 TTC3 USP4 UXS1 VEGFA VIM WNK1 WNK4 XIAP YAP1 YBX1 YWHAZ ZFP36L1 ZHX1 15 interactors: AKT1 AURKB DDX58 HDAC6 IKBKG ITCH MAPRE1 OPTN PPP2R4 TRAF2 TRAF6 TRAF7 TRAIP TUBA1A UBE2S
Entrez ID 207 1540
HPRD ID 01261 05427
Ensembl ID ENSG00000142208 ENSG00000083799
Uniprot IDs B0LPE5 B3KVH4 P31749 Q9NQC7
PDB IDs 1H10 1UNP 1UNQ 1UNR 2UVM 2UZR 2UZS 3CQU 3CQW 3MV5 3MVH 3O96 3OCB 3OW4 3QKK 3QKL 3QKM 4EJN 4EKK 4EKL 4GV1 1IXD 1WHL 1WHM 2VHF
Enriched GO Terms of Interacting Partners?
Tagcloud ?
advance  catenin  contributes  decreasing  deregulation  doi  dramatically  foxo1  glioma  gliomas  implicate  inducing  insights  introduction  invasion  january  micrornas  mir  mirnas  onc  oncogene  online  phosphorylated  publication  silencing  suppressed  tissues  tumorigenesis  unfavorable 
181b  adjacent  array  assays  blot  coding  colony  corroboration  deregulated  downregulation  luciferase  micro  micrornas  mir  mirnas  mtt  oncogenes  papillary  promoted  putative  qpcr  reporter  rnas  specimens  thyroid  tpc1  untranslated  utr  validate 
Tagcloud (Difference) ?
advance  catenin  contributes  decreasing  deregulation  doi  dramatically  foxo1  glioma  gliomas  implicate  inducing  insights  introduction  invasion  january  onc  oncogene  online  phosphorylated  publication  silencing  suppressed  tissues  tumorigenesis  unfavorable 
181b  adjacent  array  assays  blot  coding  colony  corroboration  deregulated  downregulation  luciferase  micro  mtt  oncogenes  papillary  promoted  putative  qpcr  reporter  rnas  specimens  thyroid  tpc1  untranslated  utr  validate 
Tagcloud (Intersection) ?
micrornas  mir  mirnas