Wiki-Pi
About
Search
People
Updates
Search
AKT1 and CHEK1
Number of citations of the paper that reports this interaction (PubMedID
28319113
)
39
Data Source:
BioGRID
(genetic interference)
HPRD
(in vitro)
AKT1
CHEK1
Description
AKT serine/threonine kinase 1
checkpoint kinase 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Mitochondrial Intermembrane Space
Endoplasmic Reticulum
Spindle
Cytosol
Plasma Membrane
Cell-cell Junction
Cilium
Cell Cortex
Microtubule Cytoskeleton
Membrane
Lamellipodium
Vesicle
Protein-containing Complex
Ciliary Basal Body
Postsynapse
Glutamatergic Synapse
Chromosome, Telomeric Region
Chromatin
Condensed Nuclear Chromosome
Extracellular Space
Nucleus
Nucleoplasm
Replication Fork
Chromosome
Cytoplasm
Centrosome
Cytosol
Cytoskeleton
Protein-containing Complex
Molecular Function
Nucleotide Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
Calmodulin Binding
ATP Binding
Phosphatidylinositol-3,4,5-trisphosphate Binding
Kinase Activity
Transferase Activity
Enzyme Binding
Kinase Binding
Protein Kinase Binding
Nitric-oxide Synthase Regulator Activity
Protein Serine/threonine Kinase Inhibitor Activity
Identical Protein Binding
Protein Homodimerization Activity
Phosphatidylinositol-3,4-bisphosphate Binding
14-3-3 Protein Binding
Potassium Channel Activator Activity
Protein Serine Kinase Activity
TORC2 Complex Binding
Nucleotide Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Protein Domain Specific Binding
Histone H3T11 Kinase Activity
Protein Serine Kinase Activity
Biological Process
Osteoblast Differentiation
Maternal Placenta Development
Positive Regulation Of Endothelial Cell Proliferation
Cell Migration Involved In Sprouting Angiogenesis
Cytoplasmic Translation
Complement Receptor Mediated Signaling Pathway
Sphingosine-1-phosphate Receptor Signaling Pathway
Glycogen Metabolic Process
Glycogen Biosynthetic Process
Regulation Of Glycogen Biosynthetic Process
Glucose Metabolic Process
Gluconeogenesis
Translational Initiation
Regulation Of Translation
Protein Phosphorylation
Ubiquitin-dependent Protein Catabolic Process
Protein Import Into Nucleus
NLS-bearing Protein Import Into Nucleus
Nitric Oxide Biosynthetic Process
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Golgi To Plasma Membrane Transport
Apoptotic Process
Activation-induced Cell Death Of T Cells
Inflammatory Response
Response To Oxidative Stress
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Germ Cell Development
Nervous System Development
Cell Population Proliferation
Insulin Receptor Signaling Pathway
Apoptotic Mitochondrial Changes
Cellular Response To Starvation
Response To Heat
Response To Hormone
Gene Expression
Negative Regulation Of Autophagy
Positive Regulation Of Endothelial Cell Migration
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane
Fibroblast Migration
Positive Regulation Of Fibroblast Migration
Positive Regulation Of Sodium Ion Transport
Positive Regulation Of Glucose Metabolic Process
Regulation Of Neuron Projection Development
Negative Regulation Of Macroautophagy
Phosphorylation
Cell Migration
Protein Ubiquitination
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Cytokine-mediated Signaling Pathway
Mammalian Oogenesis Stage
Cell Differentiation
Protein Catabolic Process
Positive Regulation Of Cell Growth
Regulation Of Cell Migration
Positive Regulation Of Cell Migration
Negative Regulation Of Cell Migration
Anaphase-promoting Complex-dependent Catabolic Process
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
T Cell Costimulation
Negative Regulation Of Protein Ubiquitination
Regulation Of Myelination
Lipopolysaccharide-mediated Signaling Pathway
Cellular Response To Nutrient Levels
TOR Signaling
Negative Regulation Of Fatty Acid Beta-oxidation
Positive Regulation Of Endodeoxyribonuclease Activity
Response To Food
Peripheral Nervous System Myelin Maintenance
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Insulin Stimulus
Regulation Of Protein Localization
Positive Regulation Of Peptidyl-serine Phosphorylation
Cellular Response To Stress
Negative Regulation Of Toll-like Receptor Signaling Pathway
Positive Regulation Of Toll-like Receptor Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Cellular Response To Amino Acid Starvation
Response To Fluid Shear Stress
Protein K29-linked Ubiquitination
Intracellular Signal Transduction
Interleukin-18-mediated Signaling Pathway
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Cellular Response To Decreased Oxygen Levels
SREBP-SCAP Complex Retention In Endoplasmic Reticulum
TRNA Stabilization
Calcium Import Into The Mitochondrion
PERK-mediated Unfolded Protein Response
TORC1 Signaling
Glucose Homeostasis
Regulation Of Apoptotic Process
Golgi To Plasma Membrane Protein Transport
Negative Regulation Of Apoptotic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Anoikis
Regulation Of MRNA Stability
Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Cholesterol Biosynthetic Process
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of Cilium Assembly
Positive Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Notch Signaling Pathway
Negative Regulation Of Proteolysis
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Translational Initiation
Positive Regulation Of Translational Initiation
Nitric Oxide Metabolic Process
Positive Regulation Of D-glucose Import
Positive Regulation Of Organ Growth
Protein Autophosphorylation
Positive Regulation Of Lipid Biosynthetic Process
Insulin-like Growth Factor Receptor Signaling Pathway
Behavioral Response To Pain
Positive Regulation Of Smooth Muscle Cell Proliferation
Striated Muscle Cell Differentiation
Positive Regulation Of Protein Metabolic Process
Protein Maturation
Excitatory Postsynaptic Potential
Response To Growth Hormone
Regulation Of Vesicle-mediated Transport
Mammary Gland Epithelial Cell Differentiation
Labyrinthine Layer Blood Vessel Development
Protein Localization To Cilium
Response To UV-A
Response To Growth Factor
Protein Localization To Endoplasmic Reticulum
Protein K11-linked Ubiquitination
Cellular Response To Calcium Ion
Cellular Response To Tumor Necrosis Factor
Cellular Response To Growth Factor Stimulus
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Prostaglandin E Stimulus
Tricarboxylic Acid Metabolic Process
Establishment Of Protein Localization To Mitochondrion
Maintenance Of Protein Location In Mitochondrion
Cellular Response To Rapamycin
Protein K6-linked Ubiquitination
Negative Regulation Of Release Of Cytochrome C From Mitochondria
Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus
Execution Phase Of Apoptosis
Vascular Endothelial Cell Response To Laminar Fluid Shear Stress
Regulation Of Postsynapse Organization
TRNA (guanine-N7)-methylation
Regulation Of TRNA Methylation
Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus
CGAS/STING Signaling Pathway
Negative Regulation Of Protein Localization To Lysosome
Negative Regulation Of CGAS/STING Signaling Pathway
Beta-arrestin-dependent Dopamine Receptor Signaling Pathway
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Protein Localization To Nucleus
Cellular Response To Peptide
Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Cilium Assembly
Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Leukocyte Cell-cell Adhesion
Positive Regulation Of Protein Localization To Plasma Membrane
Negative Regulation Of Protein Maturation
Negative Regulation Of Hydrogen Peroxide-induced Neuron Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of PERK-mediated Unfolded Protein Response
Negative Regulation Of TORC1 Signaling
Positive Regulation Of TORC1 Signaling
Positive Regulation Of TORC2 Signaling
Positive Regulation Of Protein Localization To Endoplasmic Reticulum
Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process
Cellular Response To Nerve Growth Factor Stimulus
Response To Insulin-like Growth Factor Stimulus
Positive Regulation Of Protein Localization To Cell Surface
Regulation Of Type B Pancreatic Cell Development
Negative Regulation Of Lymphocyte Migration
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
DNA Damage Checkpoint Signaling
G2/M Transition Of Mitotic Cell Cycle
Inner Cell Mass Cell Proliferation
DNA Replication
DNA Repair
Chromatin Remodeling
Protein Phosphorylation
Apoptotic Process
DNA Damage Response
Nucleus Organization
Nuclear Envelope Organization
Mitotic Nuclear Membrane Disassembly
Mitotic G2 DNA Damage Checkpoint Signaling
Regulation Of Gene Expression
Regulation Of Double-strand Break Repair Via Homologous Recombination
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Peptidyl-threonine Phosphorylation
Regulation Of Cell Population Proliferation
Signal Transduction In Response To DNA Damage
Mitotic G2/M Transition Checkpoint
Positive Regulation Of Cell Cycle
Negative Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Mitotic Nuclear Division
Regulation Of Mitotic Centrosome Separation
Negative Regulation Of G0 To G1 Transition
Cellular Response To Mechanical Stimulus
Replicative Senescence
Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Cell Cycle Phase Transition
Apoptotic Process Involved In Development
Pathways
Activation of BAD and translocation to mitochondria
PIP3 activates AKT signaling
PIP3 activates AKT signaling
Downregulation of ERBB2:ERBB3 signaling
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
MTOR signalling
AKT phosphorylates targets in the cytosol
AKT phosphorylates targets in the cytosol
AKT phosphorylates targets in the nucleus
Negative regulation of the PI3K/AKT network
eNOS activation
AKT-mediated inactivation of FOXO1A
Integrin signaling
Deactivation of the beta-catenin transactivating complex
CD28 dependent PI3K/Akt signaling
Co-inhibition by CTLA4
G beta:gamma signalling through PI3Kgamma
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
KSRP (KHSRP) binds and destabilizes mRNA
VEGFR2 mediated vascular permeability
TP53 Regulates Metabolic Genes
Constitutive Signaling by AKT1 E17K in Cancer
Interleukin-4 and Interleukin-13 signaling
Regulation of TP53 Degradation
Regulation of TP53 Activity through Acetylation
Regulation of TP53 Activity through Association with Co-factors
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Cyclin E associated events during G1/S transition
Cyclin A:Cdk2-associated events at S phase entry
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1
RAB GEFs exchange GTP for GDP on RABs
RUNX2 regulates genes involved in cell migration
Regulation of PTEN stability and activity
Extra-nuclear estrogen signaling
Negative regulation of NOTCH4 signaling
FLT3 Signaling
Regulation of localization of FOXO transcription factors
Estrogen-dependent nuclear events downstream of ESR-membrane signaling
KEAP1-NFE2L2 pathway
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
Mitochondrial unfolded protein response (UPRmt)
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes
Signaling by SCF-KIT
Activation of ATR in response to replication stress
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
TP53 Regulates Transcription of DNA Repair Genes
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Transcriptional Regulation by E2F6
Drugs
ATP
Arsenic trioxide
Genistein
Inositol 1,3,4,5-Tetrakisphosphate
Resveratrol
Archexin
Enzastaurin
Perifosine
N-[2-(5-methyl-4H-1,2,4-triazol-3-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine
XL844
Enzastaurin
CHIR-124
N-{5-[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]-1H-PYRROLO[2,3-B]PYRIDIN-3-YL}NICOTINAMIDE
3-(5-{[4-(AMINOMETHYL)PIPERIDIN-1-YL]METHYL}-1H-INDOL-2-YL)QUINOLIN-2(1H)-ONE
2,2'-{[9-(HYDROXYIMINO)-9H-FLUORENE-2,7-DIYL]BIS(OXY)}DIACETIC ACID
(2S)-1-AMINO-3-[(5-NITROQUINOLIN-8-YL)AMINO]PROPAN-2-OL
2-(cyclohexylamino)benzoic acid
3-(5-{[4-(AMINOMETHYL)PIPERIDIN-1-YL]METHYL}-1H-INDOL-2-YL)-1H-INDAZOLE-6-CARBONITRILE
(3Z)-6-(4-HYDROXY-3-METHOXYPHENYL)-3-(1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDRO-2H-INDOL-2-ONE
5-ETHYL-3-METHYL-1,5-DIHYDRO-4H-PYRAZOLO[4,3-C]QUINOLIN-4-ONE
(5-{3-[5-(PIPERIDIN-1-YLMETHYL)-1H-INDOL-2-YL]-1H-INDAZOL-6-YL}-2H-1,2,3-TRIAZOL-4-YL)METHANOL
1-(5-CHLORO-2-METHOXYPHENYL)-3-{6-[2-(DIMETHYLAMINO)-1-METHYLETHOXY]PYRAZIN-2-YL}UREA
(3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLATE
18-CHLORO-11,12,13,14-TETRAHYDRO-1H,10H-8,4-(AZENO)-9,15,1,3,6-BENZODIOXATRIAZACYCLOHEPTADECIN-2-ONE
1-(5-CHLORO-2,4-DIMETHOXYPHENYL)-3-(5-CYANOPYRAZIN-2-YL)UREA
4-(6-{[(4-METHYLCYCLOHEXYL)AMINO]METHYL}-1,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)BENZOIC ACID
4-[3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOL-6-YL]-2-METHOXYPHENOL
(2R)-1-[(5,6-DIPHENYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)AMINO]PROPAN-2-OL
(2R)-3-{[(4Z)-5,6-DIPHENYL-6,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-YLIDENE]AMINO}PROPANE-1,2-DIOL
N-(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)GLYCINE
(5,6-DIPHENYL-FURO[2,3-D]PYRIMIDIN-4-YLAMINO)-ACETIC
3-AMINO-3-BENZYL-[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE
3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE
2-[5,6-BIS-(4-METHOXY-PHENYL)-FURO[2,3-D]PYRIMIDIN-4-YLAMINO]-ETHANOL
2-[(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)AMINO]ETHANOL
REL-(9R,12S)-9,10,11,12-TETRAHYDRO-9,12-EPOXY-1H-DIINDOLO[1,2,3-FG:3',2',1'-KL]PYRROLO[3,4-I][1,6]BENZODIAZOCINE-1,3(2H)-DIONE
1-[(2S)-4-(5-phenyl-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl]methanamine
N-(4-OXO-5,6,7,8-TETRAHYDRO-4H-[1,3]THIAZOLO[5,4-C]AZEPIN-2-YL)ACETAMIDE
5,6,7,8-TETRAHYDRO[1]BENZOTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONE
[4-amino-2-(tert-butylamino)-1,3-thiazol-5-yl](phenyl)methanone
2-(methylsulfanyl)-5-(thiophen-2-ylmethyl)-1H-imidazol-4-ol
6-MORPHOLIN-4-YL-9H-PURINE
1-[(2S)-4-(5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-4-YL)MORPHOLIN-2-YL]METHANAMINE
Prexasertib
Fostamatinib
LY-2608204
PF-477736
Diseases
PTEN hamartoma tumor syndrome (PHTS), including: Cowden syndrome; Bannayan-Riley-Ruvalcaba syndrome; Proteus syndrome; Proteus-like syndrome
GWAS
Apolipoprotein A1 levels (
32203549
)
Endometrial cancer (
27135401
)
Endometrial endometrioid carcinoma (
27135401
)
HDL cholesterol (
24097068
25961943
30275531
)
HDL cholesterol levels (
28334899
32203549
)
Neutrophil count (
32888494
)
Vitamin C levels (
33203707
)
Breast cancer (survival) (
25890600
)
Squamous cell lung carcinoma (
28604730
)
Interacting Genes
396 interacting genes:
ABI1
ABRAXAS1
ACAP1
ACAT2
AGAP2
AGR3
AHNAK
AHSA1
AKT1S1
AKT2
AKTIP
ALYREF
AMBRA1
APLP2
APOE
APOH
APP
APPL1
AR
ARAF
ARFIP2
ARHGAP9
ARHGEF16
ARHGEF28
ARNT
ATXN1
AURKA
BABAM1
BAD
BAG6
BCL10
BCL2L1
BCL2L11
BCL3
BECN1
BEX1
BLVRA
BPGM
BRAF
BRCA1
BTRC
BUB1
C1orf174
CAMKK1
CARHSP1
CASC3
CASP3
CASP9
CASTOR1
CBLC
CCDC88A
CCND2
CCNE1
CCNF
CCNI
CCT2
CD44
CDC37
CDH1
CDK1
CDK4
CDK6
CDKN1A
CDKN1B
CDKN1C
CDKN2A
CDKN2B
CDKN2C
CEP57L1
CEP76
CGGBP1
CHEK1
CHUK
CLASP2
CLIP3
CLK2
CMTM8
CNKSR3
CNOT9
CREB1
CREBBP
CSNK2A1
CTDP1
CTDSP2
CTNNA1
CTNNB1
CYLD
DAB2IP
DCTN1
DDIT4L
DLC1
DNAJB1
DNMT1
EEF1G
EFHC1
EIF4EBP1
ELAVL1
EMSY
ENO2
EP300
EPHA2
EPSTI1
ERBB2
ESR1
ESR2
EZH2
FAF1
FAM168A
FANCA
FANCI
FASN
FBXO31
FBXW7
FGFR4
FOXO1
FOXO3
FOXO4
FUS
FXN
GAB1
GAB2
GATA1
GATA2
GET4
GFAP
GJA1
GLIS2
GMPPA
GPT2
GRB10
GRIN2A
GSK3A
GSK3B
H2BC21
H2BC3
HEATR3
HIF1A
HMOX1
HSP90AA1
HSP90AB1
HSPB1
HTT
IKBKB
IL13RA2
IL24
ILK
IMPDH2
IRAK1
IRS1
ISCA2
ITCH
ITGB3
ITPKB
ITPR1
ITPR3
IWS1
JADE1
KANK1
KAT2A
KAT2B
KAT6A
KDELR2
KLHL3
KLRC1
KMT2D
KRT10
LANCL2
LATS2
LRRK2
LTB4R2
MAGEB1
MAP2K3
MAP2K4
MAP2K5
MAP2K6
MAP3K11
MAP3K5
MAP3K8
MAPK4
MAPK8
MAPK8IP1
MAPK9
MAPKAP1
MAPKAPK2
MAPT
MARK4
MATK
MDM2
MDM4
MEF2D
MESD
METTL1
MLF2
MLH3
MOK
MRC2
MS4A2
MSH2
MST1R
MTA3
MTCP1
MTOR
MTUS2
MUL1
MXD1
MYC
NCF2
NCKIPSD
NCOA4
NCOR2
NEDD4
NEDD4L
NF1
NF2
NGB
NHERF1
NIBAN1
NKD1
NLGN3
NOL4
NOS3
NOTCH1
NR4A1
NRAS
NRIP2
NSD3
OFD1
OSBPL11
OSGIN1
OTUD1
OXSR1
PAK1
PCGF2
PCK1
PDE3A
PDE3B
PDGFRA
PDHB
PDK1
PDK2
PDPK1
PEA15
PFKFB1
PFKFB2
PFKP
PHB2
PI4K2B
PIAS1
PIAS2
PICK1
PIK3CA
PIK3R1
PIP5K1C
PKN2
PLCG1
PLEKHO1
PLP1
PLXNA1
PMS2
POP4
POP7
PPARGC1B
PPL
PPM1A
PPM1H
PPP1CA
PPP1R11
PPP2CA
PPP2R1A
PRG2
PRKAR1A
PRKCQ
PRKCZ
PRKDC
PSMC5
PSRC1
PTEN
PTGDS
PTPA
PTPN1
PTPN11
PTPN3
PYCR3
PYGO2
RAB3D
RAC1
RAF1
RAP1GDS1
RARA
RASL10B
RASSF1
REPS1
REX1BD
RGCC
RHEBL1
RNF11
RNF115
RPS6KB1
RUVBL2
S100A14
S1PR1
SERPINB5
SETDB1
SFMBT2
SH2B2
SH3RF1
SHANK2
SHQ1
SIRPA
SIRT1
SIRT6
SKI
SKP2
SLFN5
SMAD2
SMAD3
SMAD4
SMAD7
SMARCB1
SMARCC1
SNCA
SNCB
SORBS1
SORBS2
SOX4
SP1
SP3
SPACA6
SPATA33
SRC
SRPK2
SRR
SSH1
ST14
STAT1
STK11
STK3
STK4
STOX1
SULT4A1
SUPT6H
SYTL1
TBC1D4
TBC1D7
TBCE
TCL1A
TCL1B
TCL6
TEAD2
TERF2IP
TERT
TFF1
THEM4
THRSP
TLR2
TMCC2
TNFRSF1A
TNFSF11
TNK2
TOPBP1
TP53
TRAF6
TRIB3
TRIM13
TRIM24
TRIT1
TRMT2B
TSC1
TSC2
TTC3
UBE2S
UCHL1
UHRF1
URI1
USP10
USP4
USP50
UXS1
VEGFA
VHL
VIM
WDR53
WEE1
WNK1
WNK4
XAF1
XIAP
YAP1
YBX1
YIF1B
YWHAZ
ZC3HAV1
ZFP36L1
ZHX1
ZNF691
ZRANB1
61 interacting genes:
AATF
AKT1
APP
ATM
ATR
ATXN3
BAD
BCL2L1
BLM
BRCA1
BRCA2
CDC14B
CDC25A
CDC25B
CDC25C
CDH1
CEBPA
CHUK
CLSPN
CNTN2
CSNK2B
CUL1
CUL4A
DBF4
DTL
FANCE
HSP90AA1
ILKAP
LATS2
MAPT
MCM6
MCM7
MCPH1
MDM4
MED1
NPM1
PIGM
PPP1R12A
PRKAA1
PRKDC
RAD23A
RAD51
RB1
RELA
SMAD4
TIMELESS
TLK1
TOPBP1
TP53
TP53BP1
TRAF4
UBA1
UBA2
UBB
UBC
UBE2T
USP3
XIAP
XPO1
XRCC6
YWHAG
Entrez ID
207
1111
HPRD ID
01261
04356
Ensembl ID
ENSG00000142208
ENSG00000149554
Uniprot IDs
B0LPE5
B3KVH4
P31749
B4DT73
E7EPP6
O14757
PDB IDs
1H10
1UNP
1UNQ
1UNR
2UVM
2UZR
2UZS
3CQU
3CQW
3MV5
3MVH
3O96
3OCB
3OW4
3QKK
3QKL
3QKM
4EJN
4EKK
4EKL
4GV1
5KCV
6BUU
6CCY
6HHF
6HHG
6HHH
6HHI
6HHJ
6NPZ
6S9W
6S9X
7APJ
7MYX
7NH4
7NH5
8JOW
8UVY
8UW2
8UW7
8UW9
8ZPU
1IA8
1NVQ
1NVR
1NVS
1ZLT
1ZYS
2AYP
2BR1
2BRB
2BRG
2BRH
2BRM
2BRN
2BRO
2C3J
2C3K
2C3L
2CGU
2CGV
2CGW
2CGX
2E9N
2E9O
2E9P
2E9U
2E9V
2GDO
2GHG
2HOG
2HXL
2HXQ
2HY0
2QHM
2QHN
2R0U
2WMQ
2WMR
2WMS
2WMT
2WMU
2WMV
2WMW
2WMX
2X8D
2X8E
2X8I
2XEY
2XEZ
2XF0
2YDI
2YDJ
2YDK
2YER
2YEX
2YM3
2YM4
2YM5
2YM6
2YM7
2YM8
2YWP
3F9N
3JVR
3JVS
3NLB
3OT3
3OT8
3PA3
3PA4
3PA5
3TKH
3TKI
3U9N
4FSM
4FSN
4FSQ
4FSR
4FST
4FSU
4FSW
4FSY
4FSZ
4FT0
4FT3
4FT5
4FT7
4FT9
4FTA
4FTC
4FTI
4FTJ
4FTK
4FTL
4FTM
4FTN
4FTO
4FTQ
4FTR
4FTT
4FTU
4GH2
4HYH
4HYI
4JIK
4QYE
4QYF
4QYG
4QYH
4RVK
4RVL
4RVM
5DLS
5F4N
5OOP
5OOR
5OOT
5OP2
5OP4
5OP5
5OP7
5OPB
5OPR
5OPS
5OPU
5OPV
5OQ5
5OQ6
5OQ7
5OQ8
5WI2
6FC8
6FCF
6FCK
7AKM
7AKO
7BJD
7BJE
7BJH
7BJJ
7BJM
7BJO
7BJR
7BJX
7BK1
7BK2
7BK3
7BKN
7BKO
7MCK
7SUF
7SUG
7SUH
7SUI
7SUJ
8E80
8E81
8SIV
8SIW
8SIX
9CE4
Enriched GO Terms of Interacting Partners
?
Intracellular Signal Transduction
Regulation Of Signal Transduction
Cytosol
Regulation Of Signaling
Regulation Of Programmed Cell Death
Regulation Of Cell Communication
Regulation Of Intracellular Signal Transduction
Regulation Of Apoptotic Process
Cytoplasm
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Signal Transduction
Negative Regulation Of Signal Transduction
Positive Regulation Of Signal Transduction
Cellular Response To Stress
Regulation Of Cell Population Proliferation
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Metabolic Process
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Primary Metabolic Process
Intracellular Signaling Cassette
Regulation Of Metabolic Process
Regulation Of Protein Metabolic Process
Negative Regulation Of Intracellular Signal Transduction
Regulation Of Macromolecule Metabolic Process
Response To Stress
Regulation Of Developmental Process
Positive Regulation Of Protein Metabolic Process
Nucleus
Nucleoplasm
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Metabolic Process
Negative Regulation Of Apoptotic Process
Kinase Activity
Cellular Response To Oxygen-containing Compound
Regulation Of Cell Cycle
Protein Kinase Activity
Regulation Of Protein Stability
Cell Surface Receptor Signaling Pathway
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Multicellular Organismal Process
Protein Modification Process
Regulation Of Phosphorus Metabolic Process
MAPK Cascade
Protein Serine Kinase Activity
Protein Kinase Binding
Regulation Of Protein Modification Process
Regulation Of Apoptotic Signaling Pathway
DNA Damage Response
Cellular Response To Stress
Regulation Of Cell Cycle
Nucleoplasm
DNA Repair
Regulation Of Protein Metabolic Process
DNA Metabolic Process
Regulation Of Cell Cycle Phase Transition
Regulation Of Cell Cycle Process
Response To Stress
Macromolecule Metabolic Process
Regulation Of Primary Metabolic Process
Nucleus
Response To Radiation
Intracellular Signal Transduction
Regulation Of Cell Cycle G2/M Phase Transition
Nucleic Acid Metabolic Process
Regulation Of Metabolic Process
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Response To Ionizing Radiation
Signal Transduction In Response To DNA Damage
Nucleobase-containing Compound Metabolic Process
Regulation Of Mitotic Cell Cycle
Positive Regulation Of Protein Metabolic Process
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Protein Modification Process
DNA Damage Checkpoint Signaling
Negative Regulation Of Cell Cycle
Cellular Response To Ionizing Radiation
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Response To Gamma Radiation
Regulation Of Cellular Response To Stress
Negative Regulation Of Cell Cycle Process
Cellular Response To Radiation
Regulation Of DNA Metabolic Process
Double-strand Break Repair
Negative Regulation Of Cell Cycle Phase Transition
Response To Xenobiotic Stimulus
Mitotic DNA Damage Checkpoint Signaling
Regulation Of Protein Catabolic Process
Mitotic DNA Integrity Checkpoint Signaling
Response To X-ray
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Cell Cycle
Mitotic G2/M Transition Checkpoint
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Identical Protein Binding
Protein Modification Process
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?