DDX26B and CEP63

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		DDX26B	CEP63
Gene Name		DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B	centrosomal protein 63kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Spindle Pole Centrosome Centriole Cytosol
	Molecular Function		Protein Binding
	Biological Process		DNA Damage Checkpoint G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Nuclear Division Centriole Replication Signal Transduction In Response To DNA Damage Spindle Assembly Cell Division
Pathways			Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Height ( 18391952)
Protein-Protein Interactions		2 interactors: CEP63 MAPK14	44 interactors: ALOX5 ARFIP2 ARNT2 CAMKK2 CCDC14 CCNI CEP57 CEP57L1 DDX26B DISC1 DST DTNB DZIP3 EXOC4 EZH2 FAM161A FBF1 GSE1 HAUS1 KXD1 MACF1 MBIP NCOR2 NDEL1 NXT2 PCNXL4 POLR3C PPP1R13B PPP4R1 SMARCE1 SMC3 SNRNP70 SPTAN1 SPTBN1 SSX3 SYNE1 SYT17 TANK TBC1D15 TSHZ3 TXLNA TXLNB USHBP1 ZCCHC10
Entrez ID		203522	80254
HPRD ID		06618	07826
Ensembl ID		ENSG00000165359	ENSG00000182923
Uniprot IDs		Q5JSJ4	Q96MT8
PDB IDs
Enriched GO Terms of Interacting Partners?		Signal Transduction In Response To DNA Damage DNA Damage Checkpoint P38MAPK Cascade Cell Cycle Checkpoint Positive Regulation Of Brown Fat Cell Differentiation Myoblast Differentiation Involved In Skeletal Muscle Regeneration Regulation Of Brown Fat Cell Differentiation 3'-UTR-mediated MRNA Stabilization Stress-induced Premature Senescence Centriole Replication Cellular Response To DNA Damage Stimulus Positive Regulation Of Myoblast Differentiation Positive Regulation Of Myoblast Fusion Response To Muramyl Dipeptide Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Regulation Of Myoblast Fusion Centriole Assembly Cell Cycle Process Cartilage Condensation Skeletal Muscle Tissue Regeneration MRNA Stabilization Cellular Senescence Centrosome Duplication Positive Regulation Of Myotube Differentiation Regulation Of Erythrocyte Differentiation Lipopolysaccharide-mediated Signaling Pathway Cell Cycle Regulation Of Myoblast Differentiation Cellular Response To Vascular Endothelial Growth Factor Stimulus Osteoclast Differentiation Myoblast Differentiation Cellular Response To Stress Tissue Regeneration Centrosome Cycle Toll-like Receptor 5 Signaling Pathway Regulation Of MRNA Stability Toll-like Receptor 10 Signaling Pathway Positive Regulation Of Fat Cell Differentiation Regulation Of RNA Stability Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Regulation Of Myotube Differentiation Cellular Response To Ionizing Radiation Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Striated Muscle Cell Differentiation TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Fatty Acid Oxidation	Microtubule Cytoskeleton Organization Organelle Organization Cytoskeleton Organization Microtubule-based Process Cell Cycle Process Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Cell Cycle Cellular Localization Golgi To Plasma Membrane Protein Transport Cell Cycle Maintenance Of Protein Location In Cell Maintenance Of Protein Location Brain Development Maintenance Of Location In Cell Protein Localization To Organelle Head Development Anatomical Structure Development Golgi To Plasma Membrane Transport Regulation Of Cellular Component Size Positive Regulation Of Axon Extension Intermediate Filament Cytoskeleton Organization Microtubule Anchoring Protein Localization Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Leukotriene Production Involved In Inflammatory Response Kidney Smooth Muscle Cell Differentiation Ureteric Peristalsis Nervous System Development Intermediate Filament-based Process Positive Regulation Of Cell Morphogenesis Involved In Differentiation Protein Localization To Nucleus Regulation Of Cell Cycle Cell Proliferation In Forebrain Actin Filament Capping Central Nervous System Development Mitotic Cell Cycle Process Cellular Protein Localization Cerebral Cortex Radially Oriented Cell Migration Endomembrane System Organization Negative Regulation Of Actin Filament Depolymerization Developmental Process
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