ERAL1

Description		Era like 12S mitochondrial rRNA chaperone 1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Cytosol Membrane
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding GTP Binding RRNA Binding Ribosomal Small Subunit Binding
	Biological Process	Ribosomal Small Subunit Assembly Ribosome Biogenesis
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		Estimated glomerular filtration rate reduction (30%) ( 30955190) Glycated hemoglobin levels ( 28898252 34059833) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252 32888494) Mean corpuscular hemoglobin ( 28017375) Mean corpuscular volume ( 29403010) Pulse pressure ( 30224653) Red cell distribution width ( 32888494)
Novel Interacting Genes		1 novel interacting genes: TMEM97
Interacting Genes		48 interacting genes: CEP44 ECT2 EXOSC8 MIR1-1 MIR106A MIR106B MIR107 MIR122 MIR138-1 MIR141 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR199A1 MIR199A2 MIR19A MIR19B1 MIR200A MIR200B MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR29B2 MIR34B MIR451A MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7I SRSF4 SSX2IP
Entrez ID		26284
HPRD ID		08466
Ensembl ID		ENSG00000132591
Uniprot IDs		O75616
PDB IDs		8CSP 8CSQ
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA 3'-UTR Binding Extracellular Vesicle Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Translation MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cytokine Production Regulation Of MRNA Stability Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Stability Regulation Of Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Cell Migration Negative Regulation Of Angiogenesis Regulation Of Vasculature Development Negative Regulation Of Vasculature Development Negative Regulation Of Cell Motility Regulation Of Translation Regulation Of Macromolecule Metabolic Process Negative Regulation Of Locomotion Regulation Of MRNA Metabolic Process Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Protein Metabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Endothelial Cell Migration Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Multicellular Organismal Process Extracellular Space
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