ECM1 and FBLN1

Number of citations of the paper that reports this interaction (PMID 15990087)
6

Data Source:
HPRD (in vitro, two hybrid)

		ECM1	FBLN1
Gene Name		extracellular matrix protein 1	fibulin 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Extracellular Space Extracellular Matrix Extracellular Vesicular Exosome	Extracellular Region Proteinaceous Extracellular Matrix Basement Membrane Extracellular Space Extracellular Matrix Extracellular Vesicular Exosome
	Molecular Function	Protease Binding Signal Transducer Activity Interleukin-2 Receptor Binding Protein Binding Protein C-terminus Binding Enzyme Binding Laminin Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding Peptidase Activator Activity
	Biological Process	Ossification Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Negative Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Type 2 Immune Response Regulation Of Transcription From RNA Polymerase II Promoter Inflammatory Response Signal Transduction Negative Regulation Of Peptidase Activity Negative Regulation Of Bone Mineralization Biomineral Tissue Development Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Angiogenesis Regulation Of T Cell Migration	Embryo Implantation Positive Regulation Of Peptidase Activity Viral Process Extracellular Matrix Organization
Pathways			Molecules associated with elastic fibres Elastic fibre formation
Drugs
Diseases
GWAS			Temperament (bipolar disorder) ( 22365631)
Protein-Protein Interactions		8 interactors: ATN1 BNIP3L CPTP FBLN1 HSPG2 IRAK3 RERE SRPK1	35 interactors: ACAN ADAMTSL2 ADAMTSL4 APOA1 APP ATN1 BHLHE40 CACNA1A CTGF ECM1 EDC4 ELN FGB FN1 GFI1B HBEGF HSPG2 ITGB1 LTBP4 MFAP5 MOB4 NEDD1 NID1 NOTCH3 NOV PLSCR1 SKIL SMAD3 SMAD4 TAF9 TANK TCF7L2 TDGF1 VCAN YWHAQ
Entrez ID		1893	2192
HPRD ID		03727	00629
Ensembl ID		ENSG00000143369	ENSG00000077942
Uniprot IDs		Q16610	P23142 Q8NBH6
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macrophage Tolerance Induction Ceramide 1-phosphate Transport Viral Process Mitochondrial Protein Catabolic Process Negative Regulation Of Macrophage Cytokine Production Ceramide Transport	Extracellular Matrix Organization Extracellular Structure Organization Organ Development Regulation Of Cellular Component Organization System Development Multicellular Organismal Development Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Anatomical Structure Morphogenesis Anatomical Structure Development Positive Regulation Of Cell-substrate Adhesion Developmental Process Regulation Of Growth Regulation Of Cell Differentiation Regulation Of Cell Development Cardiovascular System Development Regulation Of Cell Growth Regulation Of Signaling Tissue Development Regulation Of Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Cell Death Anatomical Structure Formation Involved In Morphogenesis Transcription Initiation From RNA Polymerase II Promoter Nervous System Development Extracellular Matrix Disassembly Regulation Of Cell-substrate Adhesion Regulation Of Cell Morphogenesis Angiogenesis Positive Regulation Of Cell Development Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Response To Wounding Blood Vessel Development Vasculature Development Negative Regulation Of Cell Death Central Nervous System Development Regulation Of Protein Metabolic Process DNA-templated Transcription, Initiation Locomotion Positive Regulation Of Intracellular Signal Transduction Response To Growth Factor Wound Healing Negative Regulation Of Signal Transduction Blood Vessel Morphogenesis Positive Regulation Of Cell Differentiation Ossification Transcription From RNA Polymerase II Promoter Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud ?		aberration additionally asn condition contrary defect defective derived extracellular glycan glycosylated glycosylation lipoid lp matrix mutants mutated negatively origin proteinosis putative rare residues secretion sites spectrometry suppresses variety wide	3t3 alters anchorage arntl2 bfsp2 bmp7 celsr1 confocal deregulated etv5 exhibits filopodia fmn2 gfra2 gpm6a gpm6b graffi homologs malignancies mulv nih nln oligonucleotide oncogenes parm peri protrusions punctate semi
Tagcloud (Difference) ?		aberration additionally asn condition contrary defect defective derived extracellular glycan glycosylated glycosylation lipoid lp matrix mutants mutated negatively origin proteinosis putative rare residues secretion sites spectrometry suppresses variety wide	3t3 alters anchorage arntl2 bfsp2 bmp7 celsr1 confocal deregulated etv5 exhibits filopodia fmn2 gfra2 gpm6a gpm6b graffi homologs malignancies mulv nih nln oligonucleotide oncogenes parm peri protrusions punctate semi
Tagcloud (Intersection) ?