ECM1 and SAMD11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ECM1	SAMD11
Description		extracellular matrix protein 1	sterile alpha motif domain containing 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix Platelet Dense Granule Lumen Extracellular Exosome	Nucleus PRC1 Complex
	Molecular Function	Protease Binding Interleukin-2 Receptor Binding Extracellular Matrix Structural Constituent Protein Binding	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Histone Binding
	Biological Process	Ossification Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Negative Regulation Of Cytokine-mediated Signaling Pathway Chondrocyte Development Regulation Of Type 2 Immune Response Endochondral Bone Growth Regulation Of Transcription By RNA Polymerase II Inflammatory Response Signal Transduction Negative Regulation Of Peptidase Activity Regulation Of Bone Mineralization Negative Regulation Of Bone Mineralization Biomineral Tissue Development Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Angiogenesis Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Regulation Of T Cell Migration	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Retinal Rod Cell Development
Pathways		Platelet degranulation
Drugs
Diseases		Lipoid proteinosis; Urbach-Wiethe disease
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Migraine ( 27322543) Refractive error ( 32231278) Schizophrenia ( 28991256 30285260) Spontaneous coronary artery dissection ( 32374345 32887874) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		39 interacting genes: A1CF ACTN3 AIRIM ATN1 BCAS2 BNIP3L CPTP CYSRT1 DDIAS DTX2 ENKD1 FASLG FBLN1 FKBP6 FRS3 FXR1 GCM2 GNE GPANK1 GRN HOXC8 HSPG2 IRAK3 ITGB4 KLHL38 KRTAP5-3 KRTAP9-3 LCE2A LIN7A LMO4 MKRN3 PRKAR2B RERE SAMD11 SGTB SNRPC SRPK1 UBQLN1 UBQLN2	23 interacting genes: BPIFA1 CCHCR1 CT55 ECM1 JMJD7 KRT31 KRT34 KRTAP5-7 NFKBID PLAGL2 PLEKHF2 PRR20A PRR20B PRR20C PRR20D PRR20E REL RTL8C TRAF1 TRAF2 TRIB3 TSC1 ZMYND12
Entrez ID		1893	148398
HPRD ID		03727	10081
Ensembl ID		ENSG00000143369	ENSG00000187634
Uniprot IDs		A0A140VJI7 Q16610	A0A087WU74 A0A087WX24 Q96NU1
PDB IDs
Enriched GO Terms of Interacting Partners?		Embryo Implantation
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