ECM1 and BNIP3L

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ECM1	BNIP3L
Gene Name		extracellular matrix protein 1	BCL2/adenovirus E1B 19kDa interacting protein 3-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Extracellular Space Extracellular Matrix Extracellular Vesicular Exosome	Nuclear Envelope Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Integral Component Of Membrane Intrinsic Component Of Membrane
	Molecular Function	Protease Binding Signal Transducer Activity Interleukin-2 Receptor Binding Protein Binding Protein C-terminus Binding Enzyme Binding Laminin Binding	Protein Binding Lamin Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Ossification Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Negative Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Type 2 Immune Response Regulation Of Transcription From RNA Polymerase II Promoter Inflammatory Response Signal Transduction Negative Regulation Of Peptidase Activity Negative Regulation Of Bone Mineralization Biomineral Tissue Development Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Angiogenesis Regulation Of T Cell Migration	Viral Process Mitochondrial Protein Catabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Defense Response To Virus Mitochondrial Outer Membrane Permeabilization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ATN1 BNIP3L CPTP FBLN1 HSPG2 IRAK3 RERE SRPK1	23 interactors: BCL2 BCL2L1 BNIP3 CAMK1D CASK CLEC7A CLN8 DOK5 DUSP3 ECM1 EWSR1 FATE1 GBP2 GNB5 KLHL23 LDLRAD1 MAP1LC3A RHEB RINT1 ROBO2 SMCO4 STEAP3 TMEM11
Entrez ID		1893	665
HPRD ID		03727	07288
Ensembl ID		ENSG00000143369	ENSG00000104765
Uniprot IDs		Q16610	B0AZS9 B4DTN1 O60238 Q6IBV1
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macrophage Tolerance Induction Ceramide 1-phosphate Transport Viral Process Mitochondrial Protein Catabolic Process Negative Regulation Of Macrophage Cytokine Production Ceramide Transport	Mitochondrial Membrane Organization Mitochondrion Organization Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Defense Response Neuron Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Neuron Death Positive Regulation Of Apoptotic Signaling Pathway Apoptotic Mitochondrial Changes Response To External Stimulus Regulation Of Mitochondrion Organization Ovulation Cycle Process Negative Regulation Of Anoikis Positive Regulation Of Apoptotic Process Regulation Of Autophagy Female Gonad Development Positive Regulation Of Programmed Cell Death Ovulation Cycle Regulation Of Anoikis Development Of Primary Female Sexual Characteristics Positive Regulation Of Cell Death Regulation Of Response To DNA Damage Stimulus Response To Stress Defense Response To Protozoan Regulation Of Signal Transduction Response To Protozoan Response To Other Organism Release Of Cytochrome C From Mitochondria Mitochondrial Transport Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Biotic Stimulus Regulation Of Mitotic Cell Cycle Regulation Of Intracellular Signal Transduction Negative Regulation Of Mitochondrion Organization Negative Regulation Of Autophagy Regulation Of Mitochondrial Membrane Potential Regulation Of Signaling Positive Regulation Of Signal Transduction Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Intrinsic Apoptotic Signaling Pathway Cellular Response To Organic Substance Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Calcium Ion Transport Membrane Organization Negative Regulation Of Calcium Ion Transport Cell Communication Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Apoptotic Process See more
Tagcloud ?		aberration additionally asn condition contrary defect defective derived extracellular glycan glycosylated glycosylation lipoid lp matrix mutants mutated negatively origin proteinosis putative rare residues secretion sites spectrometry suppresses variety wide	abrogates autophagy carried connections endoplasmic er extent hct116 interest ire1 microarray nbr1 nix p62 particular perk regulates reticulum sqstm1 stages still stress subjected transcriptional transmembrane unclear unfolded upr upregulation
Tagcloud (Difference) ?		aberration additionally asn condition contrary defect defective derived extracellular glycan glycosylated glycosylation lipoid lp matrix mutants mutated negatively origin proteinosis putative rare residues secretion sites spectrometry suppresses variety wide	abrogates autophagy carried connections endoplasmic er extent hct116 interest ire1 microarray nbr1 nix p62 particular perk regulates reticulum sqstm1 stages still stress subjected transcriptional transmembrane unclear unfolded upr upregulation
Tagcloud (Intersection) ?