DTNB and PRTFDC1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DTNB	PRTFDC1
Gene Name		dystrobrevin, beta	phosphoribosyl transferase domain containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Synapse	Cytosol
	Molecular Function	Zinc Ion Binding	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Homodimerization Activity
	Biological Process		Purine Ribonucleoside Salvage Adenine Salvage Guanine Salvage GMP Salvage IMP Salvage GMP Catabolic Process Hypoxanthine Metabolic Process
Pathways
Drugs
Diseases
GWAS		Coronary heart disease ( 21347282) Height ( 18391951) Multiple myeloma ( 22120009)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		30 interactors: ABI2 ABI3 BEGAIN CCDC85B CEP55 CEP63 DMD DTNBP1 GGA1 HMG20A KIF5A KIF5B KRT31 KRT40 MTUS2 NDEL1 NUP62 PPFIA1 PPFIBP2 PRTFDC1 SNTG1 SNTG2 SPZ1 TRAF2 TSACC TXLNA USHBP1 UTRN VCP ZBTB9	12 interactors: DTNB EEF2KMT EPM2AIP1 EWSR1 FLAD1 GNPDA1 HPRT1 LGALS9B MCMBP NIF3L1 STAT5A TCL1A
Entrez ID		1838	56952
HPRD ID		09091	17917
Ensembl ID		ENSG00000138101	ENSG00000099256
Uniprot IDs		B7Z6A9 E9PEY4 O60941 Q1I0L3	Q9NRG1
PDB IDs			2JBH
Enriched GO Terms of Interacting Partners?		Cytoskeleton-dependent Intracellular Transport Cellular Localization Establishment Of Localization In Cell Microtubule-based Movement Microtubule-based Transport Regulation Of Sodium Ion Transmembrane Transporter Activity Vesicle Transport Along Microtubule Movement Of Cell Or Subcellular Component Intracellular Transport Regulation Of Sodium Ion Transmembrane Transport Generation Of Neurons Nuclear Envelope Disassembly Organelle Localization Cell Projection Organization Microtubule-based Process Regulation Of Establishment Of Protein Localization To Plasma Membrane Neurogenesis Establishment Of Vesicle Localization Axon Cargo Transport Neuron Projection Development Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Centrosome Cycle Vesicle Localization Nervous System Development Cell Projection Morphogenesis Organelle Transport Along Microtubule Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Cell-matrix Adhesion Cell Part Morphogenesis Nuclear Envelope Organization Regulation Of Sodium Ion Transport Stress Granule Disassembly Establishment Of Glial Blood-brain Barrier Regulation Of Cellular Component Organization Neuron Development Synaptic Transmission Protein Complex Assembly Regulation Of Cellular Localization Regulation Of Ion Transport Negative Regulation Of Peptidyl-cysteine S-nitrosylation Developmental Process Cell Morphogenesis Neuron Projection Morphogenesis Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Centrosome Organization Establishment Of Organelle Localization Activation Of Cysteine-type Endopeptidase Activity Mitotic Cell Cycle Process Neuron Differentiation	Positive Regulation Of Mast Cell Differentiation GMP Salvage GMP Catabolic Process Guanine Salvage Glucosamine Catabolic Process FAD Biosynthetic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Regulation Of Mast Cell Differentiation Adenine Salvage Dihydrobiopterin Metabolic Process Hypoxanthine Salvage Development Of Secondary Male Sexual Characteristics Positive Regulation Of Dopamine Metabolic Process Hypoxanthine Metabolic Process Hypoxanthine Biosynthetic Process Negative Regulation Of Mast Cell Apoptotic Process GMP Biosynthetic Process Positive Regulation Of Glycogen (starch) Synthase Activity Creatinine Metabolic Process Regulation Of Mast Cell Apoptotic Process Purine Nucleoside Monophosphate Catabolic Process Glucosamine Metabolic Process Positive Regulation Of Mast Cell Proliferation Riboflavin Metabolic Process Isoleucine Metabolic Process Allantoin Metabolic Process Purine Ribonucleoside Salvage Taurine Metabolic Process Positive Regulation Of Gamma-delta T Cell Differentiation Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Response To Organonitrogen Compound Heterocycle Metabolic Process Negative Regulation Of Erythrocyte Differentiation Prolactin Signaling Pathway GMP Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Gamma-delta T Cell Activation Development Of Secondary Female Sexual Characteristics Valine Metabolic Process Creatine Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Natural Killer Cell Differentiation Succinate Metabolic Process Regulation Of Glycogen (starch) Synthase Activity Regulation Of Gamma-delta T Cell Differentiation Development Of Secondary Sexual Characteristics Purine Ribonucleoside Catabolic Process Luteinization Positive Regulation Of Glycogen Biosynthetic Process
Tagcloud ?		attributes bis channel coassembly cp cp101 currents distinguishable dithio dtt dwell hamster insensitivity modestly nitrobenzoic noncompetitive nr1 nr2 nr2a nr2b nr2c opening ovary oxidant patches recordings redox reductant thiol
Tagcloud (Difference) ?		attributes bis channel coassembly cp cp101 currents distinguishable dithio dtt dwell hamster insensitivity modestly nitrobenzoic noncompetitive nr1 nr2 nr2a nr2b nr2c opening ovary oxidant patches recordings redox reductant thiol
Tagcloud (Intersection) ?