DTNB and NUP62

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		DTNB	NUP62
Gene Name		dystrobrevin, beta	nucleoporin 62kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Synapse	Spindle Pole Nuclear Envelope Nuclear Pore Cytoplasm Ribonucleoprotein Complex Nucleocytoplasmic Shuttling Complex Nuclear Membrane Intracellular Membrane-bounded Organelle Pore Complex
	Molecular Function	Zinc Ion Binding	Chromatin Binding Nucleocytoplasmic Transporter Activity Protein Binding Structural Constituent Of Nuclear Pore Receptor Signaling Complex Scaffold Activity SH2 Domain Binding Ubiquitin Binding Thyroid Hormone Receptor Binding PTB Domain Binding
	Biological Process		Mitotic Cell Cycle Carbohydrate Metabolic Process Transcription, DNA-templated Nucleocytoplasmic Transport Mitotic Nuclear Envelope Disassembly Cell Surface Receptor Signaling Pathway Cell Aging Cell Death Negative Regulation Of Cell Proliferation Hexose Transport Pathogenesis Hormone-mediated Signaling Pathway Regulation Of Signal Transduction Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of MAP Kinase Activity Small Molecule Metabolic Process Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Regulation Of Ras Protein Signal Transduction Negative Regulation Of Ras Protein Signal Transduction MRNA Transport Transmembrane Transport
Pathways			Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS		Coronary heart disease ( 21347282) Height ( 18391951) Multiple myeloma ( 22120009)
Protein-Protein Interactions		30 interactors: ABI2 ABI3 BEGAIN CCDC85B CEP55 CEP63 DMD DTNBP1 GGA1 HMG20A KIF5A KIF5B KRT31 KRT40 MTUS2 NDEL1 NUP62 PPFIA1 PPFIBP2 PRTFDC1 SNTG1 SNTG2 SPZ1 TRAF2 TSACC TXLNA USHBP1 UTRN VCP ZBTB9	65 interactors: ABI2 ADAM15 AGR3 ATXN7 BFSP1 BLOC1S6 C1orf216 CCDC121 CCDC146 CCDC150 CCDC153 CCDC53 CCHCR1 CENPU CEP57L1 CLIC1 CRCT1 DDX3X DGCR6 DTNB FABP3 GOPC GORASP2 GTF2E2 HAUS1 HSF2 IFT20 IK IKBIP IPO5 ISCU KANSL1 KIFC3 KLHL32 KPNA1 KPNA2 KPNB1 KRT20 LMO2 MUC1 MYO15B NFX1 NUP153 NUP54 NUP98 NUPL1 NUTF2 NXF1 NXF2 OGT OIP5 PBX2 PHF21A PIN1 PTMA RANBP2 SMARCE1 SNAPC5 SP1 SSC5D THAP1 TRAF3 TXLNA XPO1 XPO6
Entrez ID		1838	23636
HPRD ID		09091	05782
Ensembl ID		ENSG00000138101	ENSG00000213024
Uniprot IDs		B7Z6A9 E9PEY4 O60941 Q1I0L3	P37198
PDB IDs			2H4D
Enriched GO Terms of Interacting Partners?		Cytoskeleton-dependent Intracellular Transport Cellular Localization Establishment Of Localization In Cell Microtubule-based Movement Microtubule-based Transport Regulation Of Sodium Ion Transmembrane Transporter Activity Vesicle Transport Along Microtubule Movement Of Cell Or Subcellular Component Intracellular Transport Regulation Of Sodium Ion Transmembrane Transport Generation Of Neurons Nuclear Envelope Disassembly Organelle Localization Cell Projection Organization Microtubule-based Process Regulation Of Establishment Of Protein Localization To Plasma Membrane Neurogenesis Establishment Of Vesicle Localization Axon Cargo Transport Neuron Projection Development Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Centrosome Cycle Vesicle Localization Nervous System Development Cell Projection Morphogenesis Organelle Transport Along Microtubule Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Cell-matrix Adhesion Cell Part Morphogenesis Nuclear Envelope Organization Regulation Of Sodium Ion Transport Stress Granule Disassembly Establishment Of Glial Blood-brain Barrier Regulation Of Cellular Component Organization Neuron Development Synaptic Transmission Protein Complex Assembly Regulation Of Cellular Localization Regulation Of Ion Transport Negative Regulation Of Peptidyl-cysteine S-nitrosylation Developmental Process Cell Morphogenesis Neuron Projection Morphogenesis Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Centrosome Organization Establishment Of Organelle Localization Activation Of Cysteine-type Endopeptidase Activity Mitotic Cell Cycle Process Neuron Differentiation	Nucleocytoplasmic Transport Nuclear Transport Viral Process Cytoplasmic Transport MRNA Transport RNA Transport RNA Localization Intracellular Transport Nuclear Import Nucleus Organization Viral Life Cycle NLS-bearing Protein Import Into Nucleus Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Establishment Of Localization In Cell Protein Transport Protein Localization To Nucleus Cytokine-mediated Signaling Pathway Establishment Of Protein Localization Nuclear Export Cellular Localization Protein Import Into Nucleus Protein Export From Nucleus Intracellular Transport Of Virus Nuclear Envelope Organization Glucose Transport Protein Localization Cellular Response To Cytokine Stimulus Organelle Organization Protein Import Mitotic Cell Cycle Hexose Transport Cellular Protein Localization Viral Transcription Regulation Of Glucose Transport Response To Cytokine RNA Biosynthetic Process Intracellular Protein Transport Cell Cycle Carbohydrate Transport Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Cellular Response To Organic Substance Protein Localization To Organelle Gene Expression Response To Organic Substance Protein Targeting Nuclear Pore Complex Assembly Pathogenesis Establishment Of Protein Localization To Organelle Ribosomal Protein Import Into Nucleus
Tagcloud ?		attributes bis channel coassembly cp cp101 currents distinguishable dithio dtt dwell hamster insensitivity modestly nitrobenzoic noncompetitive nr1 nr2 nr2a nr2b nr2c opening ovary oxidant patches recordings redox reductant thiol	barr bblf2 bblf4 betaherpesviruses bglf4 bslf1 cotransfected dilation ebv egress epstein fg gammaherpesviruses gateways import importin lytic mpm nls nlss nucleocapsids nucleocytoplasmic nucleoporins nup153 nups pore reorganization replicating vca
Tagcloud (Difference) ?		attributes bis channel coassembly cp cp101 currents distinguishable dithio dtt dwell hamster insensitivity modestly nitrobenzoic noncompetitive nr1 nr2 nr2a nr2b nr2c opening ovary oxidant patches recordings redox reductant thiol	barr bblf2 bblf4 betaherpesviruses bglf4 bslf1 cotransfected dilation ebv egress epstein fg gammaherpesviruses gateways import importin lytic mpm nls nlss nucleocapsids nucleocytoplasmic nucleoporins nup153 nups pore reorganization replicating vca
Tagcloud (Intersection) ?