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DHX15 and PINX1
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
DHX15
PINX1
Gene Name
DEAH (Asp-Glu-Ala-His) box helicase 15
PIN2/TERF1 interacting, telomerase inhibitor 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
U12-type Spliceosomal Complex
Nucleolus
Cytoplasm
U2-type Post-mRNA Release Spliceosomal Complex
Nuclear Chromosome
Kinetochore
Condensed Chromosome Kinetochore
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Mitochondrion
Spindle
Intracellular Membrane-bounded Organelle
Molecular Function
RNA Helicase Activity
Double-stranded RNA Binding
ATP-dependent RNA Helicase Activity
Protein Binding
ATP Binding
Poly(A) RNA Binding
Protein Binding
Telomerase Inhibitor Activity
Telomeric RNA Binding
Biological Process
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Telomere Maintenance Via Telomerase
Mitotic Metaphase Plate Congression
Negative Regulation Of Cell Proliferation
Regulation Of Telomerase Activity
Negative Regulation Of Telomerase Activity
Pathways
Drugs
Diseases
GWAS
Myopia (pathological) (
23049088
)
Carotid intima media thickness (
21909108
)
Retinal vascular caliber (
21060863
)
Triglycerides (
20686565
)
Protein-Protein Interactions
12 interactors:
APBB1
DDX42
NKAP
PIN1
PINX1
PRPF40A
RBM17
TRA2A
WBP4
YWHAB
YWHAG
ZGPAT
10 interactors:
AIDA
CACYBP
DHX15
GABPA
MCRS1
MPZ
PAFAH1B2
TERF1
TERT
TP63
Entrez ID
1665
54984
HPRD ID
04553
05934
Ensembl ID
ENSG00000109606
ENSG00000254093
Uniprot IDs
O43143
Q96BK5
PDB IDs
Enriched GO Terms of Interacting Partners
?
RNA Splicing
MRNA Processing
Gene Expression
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
MRNA Metabolic Process
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
RNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Biosynthetic Process
Cell Cycle
RNA Metabolic Process
Positive Regulation Of Mitochondrion Organization
Regulation Of Cytokinesis
Negative Regulation Of Transferase Activity
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Thymidylate Synthase Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of Protein Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Phosphorylation
Regulation Of Mitochondrion Organization
Regulation Of Protein Phosphorylation
Nitrogen Compound Metabolic Process
Regulation Of Cellular Component Organization
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Regulation Of Protein Metabolic Process
Negative Regulation Of Protein Dephosphorylation
Regulation Of Phosphorylation
Positive Regulation Of Cell Death
Intrinsic Apoptotic Signaling Pathway
Regulation Of Catalytic Activity
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Phosphorus Metabolic Process
Cellular Metabolic Process
Cellular Response To Insulin Stimulus
Negative Regulation Of Protein Kinase Activity
Negative Regulation Of Telomerase Activity
Telomere Maintenance Via Telomerase
Regulation Of Protein Kinase Activity
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Negative Regulation Of Kinase Activity
Negative Regulation Of Catalytic Activity
Positive Regulation Of Intracellular Transport
Regulation Of Kinase Activity
Negative Regulation Of Cellular Protein Metabolic Process
Replicative Cell Aging
Age-dependent Telomere Shortening
Telomere Maintenance Via Telomere Shortening
Cell Aging
Aging
Telomere Maintenance Via Telomerase
RNA-dependent DNA Replication
Chromatin Modification
Telomere Maintenance Via Telomere Lengthening
Chromatin Organization
Ectoderm And Mesoderm Interaction
Epidermal Cell Division
Negative Regulation Of Production Of SiRNA Involved In RNA Interference
Telomere Maintenance
Chromosome Organization
Negative Regulation Of RNA Interference
Transcription, RNA-templated
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Squamous Basal Epithelial Stem Cell Differentiation Involved In Prostate Gland Acinus Development
Negative Regulation Of Cellular Metabolic Process
Regulation Of DNA Replication
Telomeric Loop Formation
Regulation Of Epidermal Cell Division
Telomere Formation Via Telomerase
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Female Genitalia Morphogenesis
Negative Regulation Of Megakaryocyte Differentiation
Cloacal Septation
Urinary Bladder Development
Mitotic Cell Cycle Checkpoint
Developmental Process
Regulation Of Metabolic Process
Positive Regulation Of Fibroblast Apoptotic Process
Cloaca Development
Negative Regulation Of Telomere Maintenance Via Telomerase
Prostatic Bud Formation
Regulation Of Cell Death
Negative Regulation Of Keratinocyte Differentiation
Negative Regulation Of Mesoderm Development
Telomere Assembly
Positive Regulation Of Keratinocyte Proliferation
Polarized Epithelial Cell Differentiation
Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Mitotic Cell Cycle
Positive Regulation Of Cell Cycle Process
Negative Regulation Of Hematopoietic Progenitor Cell Differentiation
Cell-cell Junction Maintenance
Negative Regulation Of Cellular Senescence
Lateral Sprouting From An Epithelium
Regulation Of Cell Cycle Phase Transition
Tagcloud
?
9r
becoming
claimed
cloning
couple
describes
examples
expresses
g4s
lowly
lpts
mbaf
mbaff
mcrs2
owing
partners
patents
pin2
positional
powerful
seem
successively
suppressorlpts
surveys
tat
telomerase
trf1
trigger
undefined
Tagcloud (Difference)
?
9r
becoming
claimed
cloning
couple
describes
examples
expresses
g4s
lowly
lpts
mbaf
mbaff
mcrs2
owing
partners
patents
pin2
positional
powerful
seem
successively
suppressorlpts
surveys
tat
telomerase
trf1
trigger
undefined
Tagcloud (Intersection)
?