PINX1 and AIDA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PINX1	AIDA
Description		PIN2 (TERF1) interacting telomerase inhibitor 1	axin interactor, dorsalization associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Chromosome, Centromeric Region Kinetochore Chromosome, Telomeric Region Nucleus Nucleoplasm Chromosome Nucleolus Mitochondrion Spindle	Cytoplasm Membrane
	Molecular Function	Nucleic Acid Binding Protein Binding Telomerase Inhibitor Activity Protein-containing Complex Binding Telomerase RNA Binding	Protein Binding Protein Domain Specific Binding Phosphatidylinositol Binding
	Biological Process	Telomere Maintenance Via Telomerase Mitotic Metaphase Chromosome Alignment Negative Regulation Of Cell Population Proliferation Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Ubiquitination Regulation Of Protein Stability Negative Regulation Of Telomere Maintenance Via Telomerase Protein Localization To Chromosome, Telomeric Region Protein Localization To Nucleolus Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Protein Localization To Nucleolus	Dorsal/ventral Pattern Formation Negative Regulation Of Protein-containing Complex Assembly Regulation Of Protein-containing Complex Assembly Negative Regulation Of JUN Kinase Activity Negative Regulation Of JNK Cascade Determination Of Ventral Identity
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Adventurousness ( 30643258) Anxiety/tension (special factor of neuroticism) ( 30867560) Aspartate aminotransferase levels ( 33547301) Autism spectrum disorder ( 30804558) Brain morphology (MOSTest) ( 32665545) Carotid intima media thickness ( 30510157 21909108) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Fish- and plant-related diet ( 32066663) General factor of neuroticism ( 30867560) General risk tolerance (MTAG) ( 30643258) Gut microbiota (beta diversity) ( 27723756) Lymphocyte count ( 27863252 32888494) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Medication use (calcium channel blockers) ( 31015401) Retinal vascular caliber ( 21060863) Serum alkaline phosphatase levels ( 33547301) Systemic lupus erythematosus ( 26316170) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Triglyceride levels ( 28334899 32154731) Triglycerides ( 30275531 24097068 20686565) Type 2 diabetes ( 30054458) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 27863252 32888494)	Coronary artery disease ( 29212778)
Interacting Genes		17 interacting genes: AIDA APP C14orf119 CACYBP EIF1AD GABPA GYS1 MCRS1 MPZ PAFAH1B2 TERF1 TERT TFRC TLK1 TNPO2 TP63 UBL5	10 interacting genes: APP DDIT4L DDX41 EMSY FAM118A LNX1 PINX1 PLEKHF2 RPL36A ZDHHC17
Entrez ID		54984	64853
HPRD ID		05934	07798
Ensembl ID		ENSG00000254093	ENSG00000186063
Uniprot IDs		Q96BK5	Q96BJ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Localization Regulation Of Protein Localization To Nucleus Nuclear Envelope Lumen Nuclear Telomere Cap Complex Telomerase Activity Regulation Of Protein Localization To Nucleolus Positive Regulation Of Protein Localization To Nucleolus Response To Manganese Ion Protein-folding Chaperone Binding Protein Homodimerization Activity Telomere Maintenance Positive Regulation Of Protein Localization To Nucleus Cellular Response To Leukemia Inhibitory Factor Response To Leukemia Inhibitory Factor Notch Signaling Pathway RNA-templated DNA Biosynthetic Process Positive Regulation Of DNA Metabolic Process Telomere Maintenance Via Telomerase Regulation Of DNA Replication Negative Regulation Of Cellular Senescence Telomeric DNA Binding Telomere Organization Amyloid-beta Complex Growth Cone Lamellipodium Response To Copper Ion Response To Metal Ion Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Establishment Of Protein Localization To Telomere Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Telomere Maintenance Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Negative Regulation Of Telomere Maintenance Via Telomere Lengthening TERT-RMRP Complex Template-free RNA Nucleotidyltransferase Positive Regulation Of Transdifferentiation RNA-directed RNA Polymerase Complex SiRNA Transcription Ectoderm And Mesoderm Interaction Epidermal Cell Division Determination Of Ventral Identity Positive Regulation Of Stem Cell Proliferation Regulation Of Cellular Senescence Acetylcholine Receptor Activator Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Lipoprotein Particle Positive Regulation Of Protein Import
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?