PIN1 and NEK6

  • Number of citations of the paper that reports this interaction (PMID 16476580)
  • 10
  • Data Source:
  • HPRD (in vitro, in vivo)

PIN1

NEK6

Gene Name peptidylprolyl cis/trans isomerase, NIMA-interacting 1 NIMA-related kinase 6
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 184 interactors: ABI2 ADAMTSL4 ADARB1 AMOT ANKRD40 AP2A1 APLP1 APP ARHGEF15 ATP5B BAG6 BCL2 BCL6 BCLAF1 CAPRIN1 CARHSP1 CASP6 CBS CCDC184 CCDC33 CCDC90B CCNB1 CCNE1 CCNK CDC25C CDC27 CDK1 CDK11A CDK11B CDK12 CDK2 CDK9 CDKN1B CENPB CEP55 CEP76 CHAMP1 CHPF CNKSR1 COL11A2 CPNE6 CSAD CSNK2A1 CSNK2A2 CSNK2B CTNNB1 DAB1 DAB2 DDAH2 DDB1 DDX17 DDX24 DDX3X DDX5 DEAF1 DHX15 DMPK DYNC1I1 EFTUD2 EIF3G EP300 ETV6 FASLG FOXO4 FOXP2 G3BP1 G3BP2 GGA2 GOLGA2 GPAA1 GPHN HADHA HEXIM2 HNRNPC HNRNPH1 HNRNPK HNRNPU HOMEZ IKZF1 IKZF3 JAKMIP2 JUN KIAA1429 KIF20B KIF5A KLHL20 KMT2B KRT31 KRT38 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP4-2 LEPR LRIF1 MAP1S MAP3K11 MAPT MCL1 MDFI MED1 MEOX2 MOCS1 MTFR1 MTUS2 MYT1 NAB2 NCOA3 NEK6 NFATC2 NONO NUP62 PABPC1 PKIB PKM PKMYT1 PLK1 PML PNMA1 POLR2A PRPF8 PRRC1 PTOV1 PTPN1 QARS RAB4A RAF1 RAI1 RARA RBBP8 RBPMS RELA REPS1 RNPS1 RPL4 RPS6KB1 SFPQ SHKBP1 SMAD3 SNRNP200 SOCS3 SPERT SREK1 SRRM1 SRRM2 SRSF11 SSBP3 STIL SUPT5H TAB3 TBC1D4 TCF4 TFG THAP7 THRAP3 TLE3 TNIP1 TOP2A TP53 TP73 TRAF1 TRAF2 TRIP6 TRMT2A TSC2 TSC22D4 TUT1 U2AF2 UBB UBQLN4 UNC119 WEE1 WIZ WRNIP1 XRCC6 ZBTB14 ZBTB22 ZBTB7B ZBTB9 ZCCHC10 ZMIZ2 ZNF446 42 interactors: AES ANKRA2 ARHGAP33 ARRB1 ATF4 CCDC36 CCDC85B CDC42 CDK7 CIR1 ERCC6L2 FAM208B HSD17B14 IKZF1 IKZF3 INCA1 KCTD5 KRT31 KRT40 LNX1 LZTS2 NECAB2 NEK9 PAK6 PHF1 PIN1 PRAM1 PRDX3 PTN RBBP6 RPS6KB1 RPS7 SGK1 SMAD4 SMURF2 TCF4 TGFBR1 TNK2 TRIM23 TRIM27 TRIP4 XIAP
Entrez ID 5300 10783
HPRD ID 03031 05348
Ensembl ID ENSG00000127445 ENSG00000119408
Uniprot IDs Q13526 Q9HC98
PDB IDs 1F8A 1I6C 1I8G 1I8H 1NMV 1NMW 1PIN 1ZCN 2F21 2ITK 2KBU 2KCF 2LB3 2M9E 2M9F 2M9I 2M9J 2Q5A 2XP3 2XP4 2XP5 2XP6 2XP7 2XP8 2XP9 2XPA 2XPB 2ZQS 2ZQT 2ZQU 2ZQV 2ZR4 2ZR5 2ZR6 3I6C 3IK8 3IKD 3IKG 3JYJ 3KAB 3KAC 3KAD 3KAF 3KAG 3KAH 3KAI 3KCE 3NTP 3ODK 3OOB 3TC5 3TCZ 3TDB
Enriched GO Terms of Interacting Partners?
Tagcloud ?
13c  15n  1h  1hn  affinities  aliphatic  assignment  backbone  betap2  complexed  detects  developmentally  enac  isomerase  nedd4  owing  peptidyl  ppxy  proline  prolyl  py  resonances  rnedd4  sequential  shifts  virtually  ww  yap65  yes 
23a  abolishes  attenuated  attenuates  berberine  biogenesis  chromatin  detecting  g2  gadd45alpha  hcc  hepatocellular  immunoblotting  mature  mediate  mediating  microrna  mir  monitored  onto  p21  precursor  prediction  reveals  suppress  suppressive  transcript  upon  validation 
Tagcloud (Difference) ?
13c  15n  1h  1hn  affinities  aliphatic  assignment  backbone  betap2  complexed  detects  developmentally  enac  isomerase  nedd4  owing  peptidyl  ppxy  proline  prolyl  py  resonances  rnedd4  sequential  shifts  virtually  ww  yap65  yes 
23a  abolishes  attenuated  attenuates  berberine  biogenesis  chromatin  detecting  g2  gadd45alpha  hcc  hepatocellular  immunoblotting  mature  mediate  mediating  microrna  mir  monitored  onto  p21  precursor  prediction  reveals  suppress  suppressive  transcript  upon  validation 
Tagcloud (Intersection) ?