ADAP1 and NCL

Number of citations of the paper that reports this interaction (PMID 12565890)
3

Data Source:
HPRD (in vitro, in vivo)

		ADAP1	NCL
Gene Name		ArfGAP with dual PH domains 1	nucleolin
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Nucleus Nucleoplasm Nucleolus Cell Cortex Membrane Ribonucleoprotein Complex Cytoplasmic Ribonucleoprotein Granule Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding ARF GTPase Activator Activity Zinc Ion Binding Inositol 1,3,4,5 Tetrakisphosphate Binding	Nucleotide Binding RNA Binding Protein Binding Protein C-terminus Binding Telomeric DNA Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Regulation Of ARF GTPase Activity Regulation Of GTPase Activity Positive Regulation Of GTPase Activity	Angiogenesis Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter
Pathways
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 23728934) Eating disorders (purging via substances) ( 23568457)
Protein-Protein Interactions		23 interactors: ANP32A AP3B2 CSNK1A1 DVL3 GADD45A GOLGA2 GSK3B NCL PIK3CA PRKCA PRKCE PRKCI PRKCZ PRKD1 PSME3 PURA RANBP9 RPS9 SDCBP2 SF3A3 SRSF2 SUB1 SUPV3L1	48 interactors: ADAP1 ADAP2 CD3E CD3EAP CDK1 CDKN2A CSNK2A1 CSNK2A2 ERG ETS1 FMR1 GRB2 GZF1 GZMA H2AFX HIST1H1C HIST2H2AC HIST2H2BE HIST3H3 HMGA1 IL7R MDC1 MDK MDM2 MYB MYBL1 NBN NDRG1 NPM1 NR3C1 PARP1 PPARGC1A PPM1D PRKCZ PTGS1 S100A11 SREK1 SSB STAU1 TERF2 TERT TOP1 TP53 VHL XRCC6 YWHAQ ZFP36 ZNF689
Entrez ID		11033	4691
HPRD ID		09733	01245
Ensembl ID		ENSG00000105963
Uniprot IDs		O75689	B3KM80 P19338 Q9BQ02
PDB IDs		3FEH 3FM8 3LJU 3MDB	2FC8 2FC9 2KRR
Enriched GO Terms of Interacting Partners?		Peptidyl-serine Phosphorylation Intracellular Signal Transduction Intracellular Transport Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Establishment Of Localization In Cell Positive Regulation Of Phosphorylation Cellular Response To Growth Factor Stimulus Positive Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Response To Growth Factor Positive Regulation Of Protein Modification Process Positive Regulation Of Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neurotrophin Signaling Pathway Negative Regulation Of Cell Death Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Protein Phosphorylation Regulation Of Protein Phosphorylation Cellular Localization Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Catalytic Activity Regulation Of Cell Death Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway Protein Phosphorylation Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of MAPK Cascade Positive Regulation Of Cell Adhesion Regulation Of Glucose Import Signaling Cellular Response To Fibroblast Growth Factor Stimulus Cell Communication Regulation Of Metabolic Process Platelet Activation Response To Fibroblast Growth Factor Negative Regulation Of Glial Cell Apoptotic Process Anatomical Structure Morphogenesis Positive Regulation Of Phospholipase Activity	Chromosome Organization DNA Conformation Change Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Cell Aging Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Cycle Chromatin Organization Response To Stimulus Nucleobase-containing Compound Metabolic Process Cellular Response To Stress DNA Packaging Cellular Response To Stimulus Developmental Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Gene Expression Regulation Of Apoptotic Process Chromatin Assembly Telomere Maintenance Cellular Nitrogen Compound Metabolic Process Cell Cycle Checkpoint Regulation Of Cell Death Chromatin Assembly Or Disassembly Response To Stress Mitotic Cell Cycle Checkpoint Regulation Of Cell Proliferation DNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cell Aging Negative Regulation Of Gene Expression Regulation Of Cell Cycle Negative Regulation Of Biosynthetic Process Aging Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Regulation Of Cellular Process RNA Biosynthetic Process Cellular Senescence Double-strand Break Repair Protein Complex Assembly DNA Damage Checkpoint Cell Cycle Process Regulation Of RNA Metabolic Process Mitotic Cell Cycle Process
Tagcloud ?			affinity capping corresponding deletion eif end eucaryotic fold free germ hairpin initiation interference leader loop mrna noncoding ovalbumin rabbit rate recognition restored reticulocyte secondary sequence structure systems translation wheat
Tagcloud (Difference) ?			affinity capping corresponding deletion eif end eucaryotic fold free germ hairpin initiation interference leader loop mrna noncoding ovalbumin rabbit rate recognition restored reticulocyte secondary sequence structure systems translation wheat
Tagcloud (Intersection) ?