ADAP1 and SUPV3L1

Number of citations of the paper that reports this interaction (PMID 16176273)
9

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		ADAP1	SUPV3L1
Gene Name		ArfGAP with dual PH domains 1	suppressor of var1, 3-like 1 (S. cerevisiae)
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Nucleus Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid Mitochondrial Degradosome
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding ARF GTPase Activator Activity Zinc Ion Binding Inositol 1,3,4,5 Tetrakisphosphate Binding	DNA Binding DNA Helicase Activity RNA Binding Double-stranded RNA Binding ATP-dependent RNA Helicase Activity Helicase Activity Protein Binding ATP Binding 3'-5' RNA Helicase Activity Protein Homodimerization Activity Poly(A) RNA Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Regulation Of ARF GTPase Activity Regulation Of GTPase Activity Positive Regulation Of GTPase Activity	Mitochondrial MRNA Catabolic Process Positive Regulation Of Mitochondrial RNA Catabolic Process Mitochondrial RNA 3'-end Processing DNA Recombination RNA Catabolic Process Positive Regulation Of Cell Growth DNA Duplex Unwinding Mitochondrial NcRNA Surveillance Mitochondrial MRNA Surveillance Negative Regulation Of Apoptotic Process Mitochondrion Morphogenesis Chromatin Maintenance Mitochondrial RNA Surveillance
Pathways
Drugs
Diseases
GWAS			Immune reponse to smallpox (secreted IL-1beta) ( 22610502)
Protein-Protein Interactions		23 interactors: ANP32A AP3B2 CSNK1A1 DVL3 GADD45A GOLGA2 GSK3B NCL PIK3CA PRKCA PRKCE PRKCI PRKCZ PRKD1 PSME3 PURA RANBP9 RPS9 SDCBP2 SF3A3 SRSF2 SUB1 SUPV3L1	2 interactors: ADAP1 LZTS2
Entrez ID		11033	6832
HPRD ID		09733	05493
Ensembl ID		ENSG00000105963	ENSG00000156502
Uniprot IDs		O75689	Q8IYB8
PDB IDs		3FEH 3FM8 3LJU 3MDB	3RC3 3RC8
Enriched GO Terms of Interacting Partners?		Peptidyl-serine Phosphorylation Intracellular Signal Transduction Intracellular Transport Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Establishment Of Localization In Cell Positive Regulation Of Phosphorylation Cellular Response To Growth Factor Stimulus Positive Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Response To Growth Factor Positive Regulation Of Protein Modification Process Positive Regulation Of Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neurotrophin Signaling Pathway Negative Regulation Of Cell Death Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Protein Phosphorylation Regulation Of Protein Phosphorylation Cellular Localization Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Catalytic Activity Regulation Of Cell Death Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway Protein Phosphorylation Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of MAPK Cascade Positive Regulation Of Cell Adhesion Regulation Of Glucose Import Signaling Cellular Response To Fibroblast Growth Factor Stimulus Cell Communication Regulation Of Metabolic Process Platelet Activation Response To Fibroblast Growth Factor Negative Regulation Of Glial Cell Apoptotic Process Anatomical Structure Morphogenesis Positive Regulation Of Phospholipase Activity	Spindle Midzone Assembly Microtubule Severing
Tagcloud ?			agenesis cassette conditional conditionally cre disrupt flp ft1 helicase illustrate insertions intronic juvenile lethality mutagenesis neutral organismal orientation permitting promiscuous recombinases recombination rescue retardation switches tol2 transposon zebrafish
Tagcloud (Difference) ?			agenesis cassette conditional conditionally cre disrupt flp ft1 helicase illustrate insertions intronic juvenile lethality mutagenesis neutral organismal orientation permitting promiscuous recombinases recombination rescue retardation switches tol2 transposon zebrafish
Tagcloud (Intersection) ?