ADAP1 and RPS9

Number of citations of the paper that reports this interaction (PubMedID 12565890)
0

Data Source:
HPRD (in vitro)

		ADAP1	RPS9
Description		ArfGAP with dual PH domains 1	ribosomal protein S9
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Ribosome Focal Adhesion Small Ribosomal Subunit Membrane Cytosolic Ribosome Cytosolic Small Ribosomal Subunit Small-subunit Processome Synapse Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Zinc Ion Binding Inositol 1,3,4,5 Tetrakisphosphate Binding Metal Ion Binding Phosphatidylinositol Bisphosphate Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Regulation Of GTPase Activity	Cytoplasmic Translation Translation Ribosomal Small Subunit Biogenesis
Pathways		Nuclear signaling by ERBB4	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency SARS-CoV-1 modulates host translation machinery SARS-CoV-2 modulates host translation machinery Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs			Artenimol
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Lymphocyte count ( 32888494) Lymphocyte percentage of white cells ( 32888494) Platelet distribution width ( 32888494)	Birth weight ( 31043758) Takayasu arteritis ( 25604533 33308445)
Interacting Genes		24 interacting genes: ANP32A AP3B2 CSNK1A1 DVL3 GADD45A GOLGA2 GSK3B NCL PIK3CA PLEKHF2 PRKCA PRKCE PRKCI PRKCZ PRKD1 PSME3 PURA RANBP9 RPS9 SDCBP2 SF3A3 SRSF2 SUB1 SUPV3L1	6 interacting genes: ADAP1 APP DUX4 PTEN STAT3 XIAP
Entrez ID		11033	6203
HPRD ID		09733	04696
Ensembl ID		ENSG00000105963	ENSG00000170889
Uniprot IDs		A0A087WTN6 A8K3A2 B4DUZ7 O75689	A8MXK4 P46781
PDB IDs		3FEH 3FM8 3LJU 3MDB	4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZUO 6ZV6 6ZVH 6ZVJ 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I 7MQ8 7MQ9 7MQA 7QP6 7QP7 7R4X 7TQL 7WTS 7WTT 7WTU 7WTV 7WTW 7WTX 7WTZ 7WU0 7XNX 7XNY 8G5Y 8G5Z 8G60 8G61 8G6J 8GLP 8IFD 8IFE 8JDJ 8JDK 8JDL 8JDM 8K2C 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPK 8PPL 8QOI 8T4S 8UKB 8XP2 8XP3 8XSX 8XSY 8XSZ 8XXL 8XXM 8XXN 8Y0W 8Y0X 8YOO 8YOP 8ZDB 8ZDC 8ZDD 9BKD 9BLN 9C3H 9G8M 9G8O
Enriched GO Terms of Interacting Partners?		Diacylglycerol-dependent Serine/threonine Kinase Activity Protein Serine Kinase Activity Protein Serine/threonine Kinase Activity Protein Phosphorylation Phosphorylation Insulin Receptor Substrate Binding Kinase Activity Intracellular Signal Transduction Protein Kinase Activity Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Positive Regulation Of Intracellular Signal Transduction Regulation Of Protein Metabolic Process PAR Polarity Complex Positive Regulation Of Protein Localization Positive Regulation Of Signal Transduction Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Response To Peptide Hormone Positive Regulation Of Cellular Component Biogenesis ATP Binding Positive Regulation Of Cell Communication Regulation Of Signal Transduction Nucleus Positive Regulation Of Signaling Regulation Of Apoptotic Process Microtubule-based Process Cellular Response To Peptide Hormone Stimulus Cellular Response To Hormone Stimulus Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Cellular Component Organization Beta-catenin Destruction Complex Response To Phorbol 13-acetate 12-myristate Regulation Of Programmed Cell Death Positive Regulation Of Cell Projection Organization Regulation Of Metabolic Process Regulation Of Autophagy Negative Regulation Of Protein Metabolic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Protein-containing Complex Assembly Negative Regulation Of Metabolic Process Negative Regulation Of Programmed Cell Death Response To Hormone Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Protein Localization Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Response To Ketone Positive Regulation Of Protein Localization To Membrane Regulation Of Intracellular Signal Transduction Regulation Of MAPK Cascade Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction	Regulation Of Cell Cycle Cell Death Apoptotic Process Intracellular Signaling Cassette Copper Ion Homeostasis Programmed Cell Death Protein Serine/threonine Kinase Binding Negative Regulation Of Cell Population Proliferation Neuron Projection Organization Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Developmental Growth Positive Regulation Of ATP Metabolic Process Modulation Of Excitatory Postsynaptic Potential Reproductive Behavior Regulation Of Glycolytic Process Canonical NF-kappaB Signal Transduction Positive Regulation Of Intracellular Signal Transduction Regulation Of Inflammatory Response Positive Regulation Of Defense Response Negative Regulation Of Multicellular Organismal Process Amyloid-beta Complex Positive Regulation Of Interleukin-1 Production Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Regulation Of MiRNA Transcription Regulation Of Multicellular Organism Growth Amylin Binding Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Interleukin-1 Beta Production Negative Regulation Of Synaptic Vesicle Clustering Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MiRNA Metabolic Process Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Cytokine Production Positive Regulation Of Biosynthetic Process Negative Regulation Of Signal Transduction Negative Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Protein Linear Polyubiquitination Regulation Of Apoptosis Involved In Tissue Homeostasis Positive Regulation Of JNK Cascade Peptidase Inhibitor Activity Acetylcholine Receptor Activator Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catabolic Process Modulation Of Chemical Synaptic Transmission Regulation Of Interleukin-1 Production
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