CLINT1 and GGA2

Number of citations of the paper that reports this interaction (PMID 12213833)
54

Data Source:
HPRD (in vitro)

		CLINT1	GGA2
Gene Name		clathrin interactor 1	golgi-associated, gamma adaptin ear containing, ARF binding protein 2
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Golgi Apparatus Cytosol Membrane Clathrin-coated Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Golgi Apparatus Trans-Golgi Network Endosome Membrane Clathrin Adaptor Complex Clathrin-coated Vesicle
	Molecular Function	Protein Binding Lipid Binding Clathrin Binding	Protein Binding ADP-ribosylation Factor Binding
	Biological Process	Post-Golgi Vesicle-mediated Transport Endocytosis Clathrin Coat Assembly Membrane Organization	Intracellular Protein Transport Vesicle-mediated Transport
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: AP1G1 AP2A1 AP2B1 CALM1 CLTC DNM1 EPS15 GGA1 GGA2 GGA3 JUN YWHAG	30 interactors: AFTPH APP ARF1 ARF3 ATXN1 BACE1 BACE2 CA8 CCDC91 CLINT1 CLTC GGA1 GGA3 HGS HTT IGF2R LRP3 M6PR PIN1 RAB5A RABEP1 RABGEF1 RNF11 SORL1 SORT1 SPG21 STAB1 SYNRG TRIM23 VPS18
Entrez ID		9685	23062
HPRD ID		06273	09347
Ensembl ID		ENSG00000113282	ENSG00000103365
Uniprot IDs		Q14677	Q9UJY4
PDB IDs		1XGW 2QY7 2V8S	1MHQ
Enriched GO Terms of Interacting Partners?		Establishment Of Localization In Cell Protein Transport Intracellular Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Cellular Localization Protein Localization Cellular Protein Localization Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus Negative Regulation Of Hyaluronan Biosynthetic Process Clathrin-mediated Endocytosis Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Antigen Processing And Presentation Of Peptide Antigen Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Golgi Vesicle Transport Regulation Of ERBB Signaling Pathway Regulation Of Defense Response To Virus Antigen Processing And Presentation Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Ephrin Receptor Signaling Pathway Receptor-mediated Endocytosis Golgi To Endosome Transport Membrane Organization Regulation Of Protein Autophosphorylation Response To External Stimulus Endosomal Transport Axon Development Cellular Response To Growth Factor Stimulus Neurotrophin TRK Receptor Signaling Pathway Response To Growth Factor Neurotrophin Signaling Pathway Receptor Internalization Regulation Of Immune System Process Cytoplasmic Transport Organelle Organization Immune System Process Nervous System Development Negative Regulation Of Protein Phosphorylation Cell Differentiation	Vesicle-mediated Transport Endocytosis Intracellular Transport Protein Transport Establishment Of Protein Localization Transport Establishment Of Localization In Cell Protein Localization Cellular Localization Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Lysosomal Transport Golgi Vesicle Transport Vacuolar Transport Cellular Protein Localization Endosomal Transport Regulation Of Vesicle-mediated Transport Endosome To Lysosome Transport Cytoplasmic Transport Visual Learning Membrane Organization Visual Behavior Protein Targeting To Lysosome Protein Localization To Lysosome Associative Learning Cellular Copper Ion Homeostasis Membrane Protein Ectodomain Proteolysis Signaling Protein Targeting To Vacuole Copper Ion Homeostasis Cell Communication Negative Regulation Of Signaling Establishment Of Protein Localization To Vacuole Learning Transition Metal Ion Homeostasis Membrane Protein Proteolysis Regulation Of Exocytosis Retrograde Vesicle-mediated Transport, Golgi To ER Regulation Of Synaptic Plasticity Regulation Of Protein Catabolic Process Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Phosphorylation Neural Plate Formation Negative Regulation Of Kit Signaling Pathway Positive Regulation Of Early Endosome To Recycling Endosome Transport Negative Regulation Of Tau-protein Kinase Activity Negative Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Negative Regulation Of Neurofibrillary Tangle Assembly Positive Regulation Of Choline O-acetyltransferase Activity
Tagcloud ?		02mum 13mum 29ml aps consolidated cyp1a2 cyp2b6 cyp2c19 cyp2c8 cyp3a4 cyp450 dpa formations hlms invitro1 isozyme ketoconazole khellactone km1 m4 m5 m6 menten metabolisms michaelis naphthoflavone praeruptorin pyranocoumarins uhplc	addressed adulthood allele attributable byg c57bl c57bl6 disrupted ear establishes gga1 gga3 ggas harbors homozygous hypomorphic insertional knockout lethality mutagenesis neonatal ola129sv placement redundancy ribosylation runted survive tigm true
Tagcloud (Difference) ?		02mum 13mum 29ml aps consolidated cyp1a2 cyp2b6 cyp2c19 cyp2c8 cyp3a4 cyp450 dpa formations hlms invitro1 isozyme ketoconazole khellactone km1 m4 m5 m6 menten metabolisms michaelis naphthoflavone praeruptorin pyranocoumarins uhplc	addressed adulthood allele attributable byg c57bl c57bl6 disrupted ear establishes gga1 gga3 ggas harbors homozygous hypomorphic insertional knockout lethality mutagenesis neonatal ola129sv placement redundancy ribosylation runted survive tigm true
Tagcloud (Intersection) ?