DNER

Gene Name		delta/notch-like EGF repeat containing
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Plasma Membrane Integral Component Of Membrane Dendrite Neuronal Cell Body
	Molecular Function	Transmembrane Signaling Receptor Activity Notch Binding Calcium Ion Binding Protein Binding Clathrin Binding
	Biological Process	Neuron Migration Endocytosis Notch Signaling Pathway Notch Receptor Processing Synapse Assembly Central Nervous System Development Glial Cell Differentiation Skeletal Muscle Fiber Development
Pathways		Signaling by NOTCH1 HD Domain Mutants in Cancer Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Activated NOTCH1 Transmits Signal to the Nucleus Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH Signaling by NOTCH1 Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS		Pulmonary function (interaction) ( 23284291)
Protein-protein Interactions		1 interactors: AP1G1
Entrez ID		92737
HPRD ID		09531
Ensembl ID		ENSG00000187957
Uniprot IDs		Q8NFT8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Natural Killer Cell Degranulation Golgi To Lysosome Transport Golgi To Vacuole Transport Endosome To Melanosome Transport Pigment Granule Maturation Cellular Pigment Accumulation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Regulated Secretory Pathway Melanosome Organization Pigment Granule Organization Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Defense Response To Virus By Virus Positive Regulation Of Natural Killer Cell Activation Regulation Of Regulated Secretory Pathway Lysosomal Transport Cellular Pigmentation Positive Regulation Of Exocytosis Developmental Pigmentation Vacuolar Transport Regulation Of Defense Response To Virus Post-Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Positive Regulation Of Leukocyte Mediated Cytotoxicity Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Pigmentation Regulation Of Exocytosis Positive Regulation Of Innate Immune Response Endosomal Transport Vesicle Organization Antigen Processing And Presentation Of Peptide Antigen Regulation Of Innate Immune Response Golgi Vesicle Transport Antigen Processing And Presentation Positive Regulation Of Cell Activation Positive Regulation Of Secretion Regulation Of Vesicle-mediated Transport Regulation Of Lymphocyte Activation Regulation Of Cell Activation Viral Process Positive Regulation Of Immune Response Regulation Of Secretion Cytoplasmic Transport Positive Regulation Of Transport
Tagcloud ?		ampar amphiphysin autoantibody caspr2 cna crmp5 csna cv2 delineated fundamentally gabaar gababr gad65 glyr hu iglons immunomodulator isa lgi1 mglur1 mglur5 oncological paraneoplastic pns ri sox vgcc yo zic4