MARCH2 and STX6

Number of citations of the paper that reports this interaction (PMID 15689499)
23

Data Source:
HPRD (in vivo, in vitro)

		MARCH2	STX6
Gene Name		membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase	syntaxin 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endosome Membrane Integral Component Of Membrane Cytoplasmic Vesicle	Golgi Membrane Early Endosome Golgi Apparatus Trans-Golgi Network Plasma Membrane Integral Component Of Membrane Clathrin-coated Vesicle SNARE Complex Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Endocytosis Protein Ubiquitination	Intracellular Protein Transport Vesicle Fusion Endosome Organization Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Golgi Ribbon Formation
Pathways
Drugs
Diseases
GWAS			Progressive supranuclear palsy ( 21685912)
Protein-Protein Interactions		8 interactors: CCDC155 CDC34 FATE1 LDLRAD1 STX6 SYNE4 UBE2D1 UBE2H	15 interactors: EEA1 GOPC GOSR2 MARCH2 NAPB PSMA3 PTPN9 SNAP23 SNAP29 STX16 STX4 STX7 VAMP4 VPS11 VPS18
Entrez ID		51257	10228
HPRD ID		14361	07231
Ensembl ID		ENSG00000099785	ENSG00000135823
Uniprot IDs		Q9P0N8	B4DR17 O43752
PDB IDs			2NPS
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Chromosome Localization To Nuclear Envelope Involved In Synapsis Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Cellular Macromolecule Catabolic Process Establishment Of Epithelial Cell Apical/basal Polarity Cell Cycle Process Positive Regulation Of Inclusion Body Assembly Golgi Ribbon Formation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Negative Regulation Of CAMP-mediated Signaling Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Establishment Of Monopolar Cell Polarity Cell Cycle Establishment Of Epithelial Cell Polarity Proteolysis Regulation Of Inclusion Body Assembly Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of CAMP-mediated Signaling Protein K11-linked Ubiquitination	Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle-mediated Transport Vesicle Organization Establishment Of Localization In Cell Membrane Organization Cellular Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Fusion To Presynaptic Membrane Transport Vesicle Docking Post-Golgi Vesicle-mediated Transport Membrane Docking Golgi Vesicle Transport Cellular Protein Localization Synaptic Vesicle Transport Intracellular Protein Transport Exocytosis Regulation Of Establishment Of Protein Localization To Plasma Membrane Organelle Organization Organelle Localization Synaptic Vesicle Exocytosis Establishment Of Vesicle Localization Golgi Ribbon Formation Vesicle Localization Secretion By Cell Regulation Of Golgi To Plasma Membrane Protein Transport Synaptic Vesicle Priming SNARE Complex Assembly Secretion Neurotransmitter Secretion Establishment Of Organelle Localization Cellular Protein Complex Assembly Regulation Of Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Neurotransmitter Transport Endosomal Transport Protein Complex Assembly Vesicle Targeting Synaptic Transmission Intra-Golgi Vesicle-mediated Transport Cellular Macromolecular Complex Assembly Cellular Component Assembly Synaptic Vesicle To Endosome Fusion Cytoplasmic Sequestering Of CFTR Protein
Tagcloud ?			alpha5beta1 alphavbeta3 boundaries c1 cho cholesterol endosome endosomes export hamster imbalance integrins interferes niemann npc1 ovary pick rab11 re recycling res restoration restores snare syntaxin tgn transferrin tuning vamp3
Tagcloud (Difference) ?			alpha5beta1 alphavbeta3 boundaries c1 cho cholesterol endosome endosomes export hamster imbalance integrins interferes niemann npc1 ovary pick rab11 re recycling res restoration restores snare syntaxin tgn transferrin tuning vamp3
Tagcloud (Intersection) ?