ZNF579 and GADD45G

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ZNF579	GADD45G
Gene Name		zinc finger protein 579	growth arrest and DNA-damage-inducible, gamma
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm
	Molecular Function	DNA Binding Poly(A) RNA Binding Metal Ion Binding	Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Activation Of MAPKKK Activity Activation Of MAPKK Activity Negative Regulation Of Protein Kinase Activity Apoptotic Process Response To Stress Multicellular Organismal Development Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of JNK Cascade Regulation Of Cell Cycle Positive Regulation Of P38MAPK Cascade
Pathways
Drugs
Diseases
GWAS			Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions		11 interactors: GADD45G ILK MAPK6 MEST NR4A1 OSGEP RASA1 RGS2 SF3B3 SPARC YAE1D1	55 interactors: AFAP1L1 APP ARPC5L CCNB1 CDK1 CDKN1A CEP57L1 CRIP2 DDAH2 EEF1A1 EEF1G EIF3G ESR1 EZH2 GADD45B GADD45GIP1 GDF9 HAP1 HP IKBKG KAT5 LRIF1 LUC7L LUC7L2 MAP3K4 MED31 MIDN PCNA PDE4DIP PDIA4 PHAX PIAS4 PLEKHM1 PPARA PPARD PPARG PPIL1 PTN PTPRK RAN RARA RBM48 RDH13 REL RWDD2B RXRA SERPINA4 SGK1 SH3GLB1 SH3GLB2 SMARCB1 TRMT2A TSNAX UTP14A ZNF579
Entrez ID		163033	10912
HPRD ID		11730	05383
Ensembl ID		ENSG00000218891	ENSG00000130222
Uniprot IDs		Q8NAF0	O95257 Q5VZ87
PDB IDs			2WAL 3FFM
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Negative Regulation Of Catalytic Activity Negative Regulation Of Transferase Activity Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Phosphorylation Negative Regulation Of Protein Metabolic Process Negative Regulation Of Phosphorylation Regulation Of Endothelial Cell Proliferation Regulation Of Cell Morphogenesis Threonylcarbamoyladenosine Biosynthetic Process Regulation Of Cytoskeleton Organization Regulation Of Cell-matrix Adhesion Regulation Of Catalytic Activity Cell Cycle Regulation Of MAPK Cascade Threonylcarbamoyladenosine Metabolic Process Developmental Process Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Regulation Of Adrenergic Receptor Signaling Pathway Ameboidal-type Cell Migration Positive Regulation Of Catalytic Activity Regulation Of Cell Death Positive Regulation Of Cardiac Muscle Contraction Platelet Activation Regulation Of Cell-substrate Adhesion Regulation Of Protein Kinase Activity Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of Phospholipase Activity Negative Regulation Of Neuron Death Activation Of MAPKKK Activity Positive Regulation Of P38MAPK Cascade Regulation Of Kinase Activity Relaxation Of Vascular Smooth Muscle Response To L-ascorbic Acid Regulation Of Intracellular Signal Transduction Relaxation Of Smooth Muscle Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Cardiac Muscle Hypertrophy Response To Lipid Regulation Of Neuron Apoptotic Process Positive Regulation Of Striated Muscle Contraction Negative Regulation Of Muscle Hypertrophy Cardiovascular System Development Intracellular Signal Transduction Fibroblast Migration Extracellular Fibril Organization Response To Gravity Negative Regulation Of Apoptotic Process	Intracellular Receptor Signaling Pathway Gene Expression RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Steroid Hormone Mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Regulation Of Gene Expression Cellular Response To Steroid Hormone Stimulus Cellular Response To Organic Cyclic Compound Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Cell Proliferation Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Ventricular Cardiac Muscle Cell Differentiation Hormone-mediated Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Death DNA-templated Transcription, Initiation Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Fibroblast Proliferation Response To Organic Cyclic Compound Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Cellular Response To Stress Cellular Response To Lipid Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Transcription, DNA-templated Cellular Response To Hormone Stimulus Positive Regulation Of Cellular Biosynthetic Process Regulation Of Catalytic Activity RNA Biosynthetic Process Regulation Of Kinase Activity Regulation Of Growth Response To Steroid Hormone Cellular Metabolic Process Positive Regulation Of Intracellular Signal Transduction
Tagcloud ?			arrest checkpoints contribute damage direct effectors encodes implicated injury kinases mapk members mitogen numerous often p38 prominent proteins repair roles signals stress ubiquitously upstream variety vivo
Tagcloud (Difference) ?			arrest checkpoints contribute damage direct effectors encodes implicated injury kinases mapk members mitogen numerous often p38 prominent proteins repair roles signals stress ubiquitously upstream variety vivo
Tagcloud (Intersection) ?