ZNF579 and RGS2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ZNF579	RGS2
Gene Name		zinc finger protein 579	regulator of G-protein signaling 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleolus Cytoplasm Mitochondrion Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Neuron Projection
	Molecular Function	DNA Binding Poly(A) RNA Binding Metal Ion Binding	GTPase Activator Activity Protein Binding Calmodulin Binding Beta-tubulin Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Regulation Of Translation Cell Cycle Spermatogenesis Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of Phospholipase Activity Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Microtubule Polymerization Termination Of G-protein Coupled Receptor Signaling Pathway Negative Regulation Of MAP Kinase Activity Positive Regulation Of GTPase Activity Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Brown Fat Cell Differentiation Relaxation Of Cardiac Muscle Relaxation Of Vascular Smooth Muscle Positive Regulation Of Cardiac Muscle Contraction Regulation Of Adrenergic Receptor Signaling Pathway
Pathways			G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: GADD45G ILK MAPK6 MEST NR4A1 OSGEP RASA1 RGS2 SF3B3 SPARC YAE1D1	58 interactors: ADCY5 ADRA1A ADRB2 ARFGAP1 BBS10 CALM1 CHD3 CLTA COMT COPB1 COPB2 CRMP1 CTSB DDR1 DUSP21 DYNLL1 EIF3L FZD5 GDE1 GIT1 GNA15 GNAI3 GNAQ GNAS HAUS5 HSPA8 IER3IP1 KIAA1377 KLK8 LIG1 LRFN1 METTL18 MON1A MTUS2 NINL NIPSNAP1 PARK2 PPP1R9B PRKCA PRKCB PRKCG PRKCSH PRKG1 RAB2A RABAC1 RAP1B REEP5 RIN3 SCN5A TSPAN15 TUBB2B UBC VPS29 WDR74 XRCC6 ZBTB48 ZNF579 ZYX
Entrez ID		163033	5997
HPRD ID		11730	02917
Ensembl ID		ENSG00000218891	ENSG00000116741
Uniprot IDs		Q8NAF0	P41220
PDB IDs			2AF0 2V4Z 4EKC 4EKD
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Negative Regulation Of Catalytic Activity Negative Regulation Of Transferase Activity Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Phosphorylation Negative Regulation Of Protein Metabolic Process Negative Regulation Of Phosphorylation Regulation Of Endothelial Cell Proliferation Regulation Of Cell Morphogenesis Threonylcarbamoyladenosine Biosynthetic Process Regulation Of Cytoskeleton Organization Regulation Of Cell-matrix Adhesion Regulation Of Catalytic Activity Cell Cycle Regulation Of MAPK Cascade Threonylcarbamoyladenosine Metabolic Process Developmental Process Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Regulation Of Adrenergic Receptor Signaling Pathway Ameboidal-type Cell Migration Positive Regulation Of Catalytic Activity Regulation Of Cell Death Positive Regulation Of Cardiac Muscle Contraction Platelet Activation Regulation Of Cell-substrate Adhesion Regulation Of Protein Kinase Activity Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of Phospholipase Activity Negative Regulation Of Neuron Death Activation Of MAPKKK Activity Positive Regulation Of P38MAPK Cascade Regulation Of Kinase Activity Relaxation Of Vascular Smooth Muscle Response To L-ascorbic Acid Regulation Of Intracellular Signal Transduction Relaxation Of Smooth Muscle Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Cardiac Muscle Hypertrophy Response To Lipid Regulation Of Neuron Apoptotic Process Positive Regulation Of Striated Muscle Contraction Negative Regulation Of Muscle Hypertrophy Cardiovascular System Development Intracellular Signal Transduction Fibroblast Migration Extracellular Fibril Organization Response To Gravity Negative Regulation Of Apoptotic Process	Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of Phospholipase Activity Platelet Activation Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Regulation Of Catalytic Activity Regulation Of Body Fluid Levels Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Response To Wounding Blood Coagulation G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Hemostasis Wound Healing Cell-cell Signaling Regulation Of Phosphorus Metabolic Process Regulation Of Adenylate Cyclase Activity Nervous System Development Regulation Of Cyclase Activity Activation Of Adenylate Cyclase Activity Signaling Response To Stress Neurotrophin Signaling Pathway Cell Communication Regulation Of Phosphorylation Dopamine Receptor Signaling Pathway Positive Regulation Of Catalytic Activity Developmental Process Positive Regulation Of Adenylate Cyclase Activity Regulation Of Kinase Activity Response To Organic Substance Cellular Response To Stimulus Regulation Of Muscle Contraction Anatomical Structure Development Regulation Of CAMP Biosynthetic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Positive Regulation Of Hydrolase Activity Cell Activation Membrane Organization Regulation Of CAMP Metabolic Process Regulation Of Protein Phosphorylation System Development Positive Regulation Of Lyase Activity Enzyme Linked Receptor Protein Signaling Pathway Golgi Vesicle Budding Adrenergic Receptor Signaling Pathway
Tagcloud ?			3t3 adipocyte already arrested beginning cloned clones differentially earliest ebpalpha hif hsp105 inducers l1 master mrnas nih nineteen place ppargamma2 preadipocyte proliferating regulators rho seemed steps takes tc10 vdr
Tagcloud (Difference) ?			3t3 adipocyte already arrested beginning cloned clones differentially earliest ebpalpha hif hsp105 inducers l1 master mrnas nih nineteen place ppargamma2 preadipocyte proliferating regulators rho seemed steps takes tc10 vdr
Tagcloud (Intersection) ?