DEDD2 and CASP8

  • Number of citations of the paper that reports this interaction (PMID 12527898)
  • 14
  • Data Source:
  • HPRD (in vivo, in vitro)

DEDD2

CASP8

Gene Name death effector domain containing 2 caspase 8, apoptosis-related cysteine peptidase
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 11 interactors: CASP10 CASP8 CDCA7L CDK6 CFLAR DEDD GTF3C3 HNRNPAB NR2E3 RBFOX2 RHOXF2 91 interactors: APAF1 APP AR ATG4D BCAP31 BCL2 BCL2L1 BFAR BID BIRC6 CASP1 CASP10 CASP14 CASP2 CASP3 CASP4 CASP6 CASP7 CASP8AP2 CASP9 CDH1 CDK11B CDKN1B CFLAR CHD3 CHUK COPS6 CRADD CTNNB1 DEDD DEDD2 EDA2R EIF2AK2 FADD FAF1 FAS FYN GMEB1 GRIA1 GZMB HDAC7 HECTD3 HIP1 IKBKB IKBKG ILK KRT18 MAP1LC3B MAP3K14 MAP4K4 MAPK1 MAPK3 MAPT NOD1 NOL3 NR1H4 PARK2 PARK7 PARP1 PARP2 PCYT1A PDIA6 PEA15 PIAS1 PICALM PLA2G4B PLEC PLIN4 PRDX6 PRKCI PRKCZ PSEN1 PSEN2 RALBP1 RB1 RIPK1 RIPK2 RYBP SNRPD3 SRF STK24 SUMO1 TFCP2 TNFRSF10A TNFRSF10B TOPORS TRAF1 TRAF2 TRAF6 USO1 VIM
Entrez ID 162989 841
HPRD ID 10868 03459
Ensembl ID ENSG00000160570 ENSG00000064012
Uniprot IDs Q8WXF8 Q14790
PDB IDs 1F9E 1I4E 1QDU 1QTN 2C2Z 2FUN 2K7Z 2Y1L 3H11 3KJN 3KJQ 4JJ7
Enriched GO Terms of Interacting Partners?
Tagcloud ?
annotation  atra  bindings  birc3  braf  casp4  casp8  changed  effector  erk  expressions  fas  fate  fenretinide  fewer  hspa1a  huh7  inducing  mek  participated  profiled  raf  ras  rxralpha  sosc2  tnfaip3  tnfalpha  traf2  uses 
10mum  abeta42  abeta43  aif  carnosic  cascades  casp3  casp4  casp9  casps  concurrently  diterpene  herbs  ingestion  initiator  labiate  monomer  neurotoxicity  neurotrophic  oligomerization  oligomers  parp  phenolic  ribose  rosemary  sage  serves  sy5y 
Tagcloud (Difference) ?
annotation  atra  bindings  birc3  braf  changed  effector  erk  expressions  fas  fate  fenretinide  fewer  hspa1a  huh7  inducing  mek  participated  profiled  raf  ras  rxralpha  sosc2  tnfaip3  tnfalpha  traf2  uses 
10mum  abeta42  abeta43  aif  carnosic  cascades  casp3  casp9  casps  concurrently  diterpene  herbs  ingestion  initiator  labiate  monomer  neurotoxicity  neurotrophic  oligomerization  oligomers  parp  phenolic  ribose  rosemary  sage  serves  sy5y 
Tagcloud (Intersection) ?
casp4  casp8