DEDD2 and DEDD

Number of citations of the paper that reports this interaction (PubMedID 12527898)
0

Data Source:
HPRD (in vivo, in vitro)

		DEDD2	DEDD
Description		death effector domain containing 2	death effector domain containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleus Nucleolus Cytoplasm
	Molecular Function	DNA Binding Protein Binding Signaling Receptor Complex Adaptor Activity	DNA Binding Protein Binding
	Biological Process	RNA Processing Apoptotic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors RRNA Catabolic Process Cellular Homeostasis Apoptotic Nuclear Changes Intracellular Signal Transduction Regulation Of Apoptotic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of Extrinsic Apoptotic Signaling Pathway	Developmental Process Involved In Reproduction Apoptotic Process Spermatogenesis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Protein Catabolic Process Regulation Of Apoptotic Process Decidualization Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Pathways
Drugs
Diseases
GWAS		Meat-related diet ( 32066663)
Interacting Genes		12 interacting genes: ATG16L1 CASP10 CASP8 CDCA7L CDK6 CFLAR DEDD GTF3C3 HNRNPAB NR2E3 RBFOX2 RHOXF2	16 interacting genes: APLP2 APP BATF2 CASP10 CASP3 CASP8 CFLAR DEDD2 FADD GTF3C1 GTF3C3 HOXD4 KRT18 KRT8 SHMT1 SMAD3
Entrez ID		162989	9191
HPRD ID		10868	06022
Ensembl ID		ENSG00000160570	ENSG00000158796
Uniprot IDs		Q8WXF8	B1AQP5 O75618
PDB IDs
Enriched GO Terms of Interacting Partners?		Ripoptosome CD95 Death-inducing Signaling Complex Death Effector Domain Binding Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Death-inducing Signaling Complex Cysteine-type Endopeptidase Activity Positive Regulation Of Neuron Apoptotic Process Extrinsic Apoptotic Signaling Pathway Death Receptor Binding Positive Regulation Of Execution Phase Of Apoptosis Cysteine-type Peptidase Activity Execution Phase Of Apoptosis Regulation Of Necroptotic Process Regulation Of Programmed Necrotic Cell Death Macrophage Differentiation Positive Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Neuron Apoptotic Process Cyclin D2-CDK6 Complex Vacuole-isolation Membrane Contact Site Regulation Of Metabolic Process Positive Regulation Of Gene Expression Mononuclear Cell Differentiation Apoptotic Signaling Pathway Regulation Of Canonical NF-kappaB Signal Transduction Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex FBXO Family Protein Binding Skeletal Myofibril Assembly Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway C-terminal Protein Lipidation Developmental Process Protein-containing Complex Binding Negative Regulation Of RNA Metabolic Process Leukocyte Differentiation Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Autophagosome Assembly Negative Regulation Of Myoblast Fusion Negative Stranded Viral RNA Replication Autophagosome Organization Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nuclear Receptor-mediated Signaling Pathway Apoptotic Process Response To Estradiol Negative Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Editing Complex Negative Regulation Of Syncytium Formation By Plasma Membrane Fusion Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Negative Regulation Of Dendrite Extension	Ripoptosome CD95 Death-inducing Signaling Complex Death-inducing Signaling Complex Extrinsic Apoptotic Signaling Pathway Death Receptor Binding Apoptotic Signaling Pathway Death Effector Domain Binding Positive Regulation Of Neuron Apoptotic Process Apoptotic Process Programmed Cell Death Cell Death Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Cysteine-type Endopeptidase Activity Positive Regulation Of Execution Phase Of Apoptosis Execution Phase Of Apoptosis Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Necroptotic Process Regulation Of Programmed Necrotic Cell Death Regulation Of Neuron Apoptotic Process Response To Anesthetic Transcription Factor TFIIIC Complex 5S Class RRNA Transcription By RNA Polymerase III Cysteine-type Peptidase Activity Response To External Biotic Stimulus Epithelial Cell Apoptotic Process Positive Regulation Of Pyroptotic Inflammatory Response TRAIL-activated Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Apoptotic Process Response To Cobalt Ion Positive Regulation Of Interleukin-1 Beta Production Regulation Of Programmed Cell Death TRNA Transcription By RNA Polymerase III TRNA Transcription RNA Polymerase III General Transcription Initiation Factor Activity Scaffold Protein Binding Positive Regulation Of Interleukin-1 Production Cell Surface Receptor Signaling Pathway Cell Body Positive Regulation Of Macrophage Differentiation Hepatocyte Apoptotic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction DNA Binding Transition Metal Ion Binding Platelet Alpha Granule Negative Regulation Of Necroptotic Process Regulation Of Interleukin-1 Beta Production Myeloid Cell Differentiation
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