DEDD2

Gene Name		death effector domain containing 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus
	Molecular Function	DNA Binding Protein Binding Receptor Signaling Complex Scaffold Activity
	Biological Process	Transcription, DNA-templated RNA Processing Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors RRNA Catabolic Process Cellular Homeostasis Apoptotic Nuclear Changes Intracellular Signal Transduction Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		11 interactors: CASP10 CASP8 CDCA7L CDK6 CFLAR DEDD GTF3C3 HNRNPAB NR2E3 RBFOX2 RHOXF2
Entrez ID		162989
HPRD ID		10868
Ensembl ID		ENSG00000160570
Uniprot IDs		Q8WXF8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Necroptotic Process Regulation Of Necrotic Cell Death Tissue Development Regulation Of Myeloid Cell Differentiation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Intracellular Receptor Signaling Pathway Organ Development Regulation Of Erythrocyte Differentiation Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Gene Expression Regulation Of Cell Proliferation Apoptotic Signaling Pathway Cell Dedifferentiation Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cell Development Programmed Cell Death Activation Of Cysteine-type Endopeptidase Activity System Development Regulation Of Metabolic Process Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Cell Death Death Extrinsic Apoptotic Signaling Pathway Regulation Of Transcription, DNA-templated Zymogen Activation Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Rhodopsin Gene Expression Negative Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter TRAIL-activated Apoptotic Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Regulation Of Rhodopsin Gene Expression Negative Regulation Of Myoblast Fusion Multicellular Organismal Development Positive Regulation Of Peptidase Activity Cell Differentiation Negative Regulation Of Gene Expression Radial Glia Guided Migration Of Purkinje Cell Regulation Of Definitive Erythrocyte Differentiation Anatomical Structure Development Negative Regulation Of Biosynthetic Process
Tagcloud ?		annotation atra bindings birc3 braf casp4 casp8 changed effector erk expressions fas fate fenretinide fewer hspa1a huh7 inducing mek participated profiled raf ras rxralpha sosc2 tnfaip3 tnfalpha traf2 uses