RHOXF1 and VTN

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RHOXF1	VTN
Gene Name		Rhox homeobox family, member 1	vitronectin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Extracellular Matrix Extracellular Vesicular Exosome Alphav-beta3 Integrin-vitronectin Complex Blood Microparticle
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding	Scavenger Receptor Activity Integrin Binding Protein Binding Heparin Binding Polysaccharide Binding Extracellular Matrix Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Multicellular Organismal Development Gamete Generation Sexual Reproduction Intracellular Steroid Hormone Receptor Signaling Pathway	Receptor-mediated Endocytosis Immune Response Cell Adhesion Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Negative Regulation Of Endopeptidase Activity Positive Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Blood Coagulation Extracellular Matrix Organization Regulation Of Complement Activation Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Binding Cell Adhesion Mediated By Integrin Endodermal Cell Differentiation Innate Immune Response Positive Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Smooth Muscle Cell-matrix Adhesion Positive Regulation Of Wound Healing
Pathways			Molecules associated with elastic fibres Syndecan interactions Regulation of Complement cascade Complement cascade Elastic fibre formation ECM proteoglycans Integrin cell surface interactions Non-integrin membrane-ECM interactions Innate Immune System
Drugs			Abciximab
Diseases
GWAS
Protein-Protein Interactions		2 interactors: NPAS2 VTN	42 interactors: ADH5 ADTRP AMPH APP CBX1 CD247 CKS2 COPS5 CRADD CSNK2A1 EGF ETV7 FGF2 FGG GEM GLUD1 GOPC HGF IGF2 IGFBP5 ITGA8 ITGB3 ITGB6 ITGB8 KNG1 LACRT PLAUR POMC PRDX4 PRKACA PRKCA PRKCB PRKCG PVR RHOXF1 RPL13A SERPINE1 SIX1 TGFB1 TGFB2 TNFRSF11B VEGFA
Entrez ID		158800	7448
HPRD ID		15954	01902
Ensembl ID		ENSG00000101883
Uniprot IDs		Q8NHV9	D9ZGG2 P04004
PDB IDs			1OC0 1S4G 1SSU 2JQ8 3BT1 3BT2
Enriched GO Terms of Interacting Partners?		Circadian Sleep/wake Cycle Locomotor Rhythm Cell Adhesion Mediated By Integrin Response To Redox State Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Circadian Behavior Rhythmic Behavior Smooth Muscle Cell-matrix Adhesion Positive Regulation Of Smooth Muscle Cell Migration Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Complement Activation Positive Regulation Of DNA Repair Positive Regulation Of Receptor-mediated Endocytosis Endodermal Cell Differentiation Regulation Of Smooth Muscle Cell Migration Positive Regulation Of Wound Healing Regulation Of Humoral Immune Response Negative Regulation Of Blood Coagulation Endoderm Formation Negative Regulation Of Coagulation Regulation Of DNA Repair Positive Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Protein Binding Negative Regulation Of Wound Healing Regulation Of Acute Inflammatory Response Circadian Regulation Of Gene Expression Endoderm Development Regulation Of Blood Coagulation Positive Regulation Of Endocytosis	Platelet Activation Platelet Degranulation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Extracellular Matrix Organization Extracellular Structure Organization Cell Activation Exocytosis Signaling Cell Communication Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Response To External Stimulus Secretion Secretion By Cell Signal Transduction Regulation Of Peptidyl-tyrosine Phosphorylation Cell Surface Receptor Signaling Pathway Positive Regulation Of Signal Transduction Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Endothelial Cell Migration Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Epithelial Cell Proliferation Negative Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Phosphorylation Response To Stimulus Cellular Response To Stimulus Positive Regulation Of Angiogenesis Regulation Of Protein Kinase Activity Positive Regulation Of MAPK Cascade Cellular Localization Positive Regulation Of Metabolic Process Regulation Of Signaling Positive Regulation Of Cell Migration Response To Stress Positive Regulation Of Cell Motility Regulation Of MAPK Cascade Regulation Of Kinase Activity Histone H3-T6 Phosphorylation Regulation Of Epithelial Cell Migration Regulation Of Cellular Process Positive Regulation Of Cellular Component Movement Positive Regulation Of Intracellular Signal Transduction
Tagcloud ?		aminomethyl aminophenyl ato benzamide carbonyl dac deacetylases decitabine demethylation deoxycytidine dimethylated dnmt dnmt1 dnmt3b entinostat hdacs homeobox homeodomain methyltransferases potencies pyridine rhox5 rhox6 rhox9 trioxide underlining ylmethoxy	accumulated aeamsq aeamsqv aeamsqvt aeamsqvtn aeamsqvtntatim desorption dimeric dimerization dissociated exclusion flight immunoblot maldi monomeric nonapeptide p17gag p24gag p2gag potently pr55gag protease proteolytic spectrometric sqnypivq succinyl suicide tof vtntatim
Tagcloud (Difference) ?		aminomethyl aminophenyl ato benzamide carbonyl dac deacetylases decitabine demethylation deoxycytidine dimethylated dnmt dnmt1 dnmt3b entinostat hdacs homeobox homeodomain methyltransferases potencies pyridine rhox5 rhox6 rhox9 trioxide underlining ylmethoxy	accumulated aeamsq aeamsqv aeamsqvt aeamsqvtn aeamsqvtntatim desorption dimeric dimerization dissociated exclusion flight immunoblot maldi monomeric nonapeptide p17gag p24gag p2gag potently pr55gag protease proteolytic spectrometric sqnypivq succinyl suicide tof vtntatim
Tagcloud (Intersection) ?