FUNDC1 and YES1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FUNDC1	YES1
Gene Name		FUN14 domain containing 1	YES proto-oncogene 1, Src family tyrosine kinase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Outer Membrane Integral Component Of Mitochondrial Outer Membrane	Cytoplasm Golgi Apparatus Microtubule Organizing Center Cytosol Actin Filament Plasma Membrane Focal Adhesion Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Receptor Binding Epidermal Growth Factor Receptor Binding Protein Binding ATP Binding Enzyme Binding Ion Channel Binding
	Biological Process	Mitochondrion Degradation Response To Hypoxia	Cellular Protein Modification Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Blood Coagulation Glucose Transport Cell Differentiation T Cell Costimulation Cellular Response To Platelet-derived Growth Factor Stimulus Peptidyl-tyrosine Autophosphorylation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Cell Proliferation Regulation Of Vascular Permeability Innate Immune Response Ephrin Receptor Signaling Pathway Leukocyte Migration Cellular Response To Peptide Hormone Stimulus
Pathways			Axon guidance Costimulation by the CD28 family EPHB-mediated forward signaling Signaling by SCF-KIT EPHA-mediated growth cone collapse Regulation of KIT signaling EPH-ephrin mediated repulsion of cells Regulation of signaling by CBL EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis FCGR activation Innate Immune System CTLA4 inhibitory signaling CD28 co-stimulation Cytokine Signaling in Immune system PECAM1 interactions Cell surface interactions at the vascular wall Signaling by ERBB2 Signaling by Interleukins Interleukin-3, 5 and GM-CSF signaling Adaptive Immune System
Drugs			Dasatinib
Diseases
GWAS		Personality dimensions ( 18957941)	Pulmonary function in asthmatics ( 23541324)
Protein-Protein Interactions		14 interactors: CTBP1 CTBP2 EHHADH GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MTERF3 SENP2 SH3GLB1 SLC25A46 SNX1 TUFM YES1	49 interactors: ADAM12 ADAM15 C1orf94 CBL CD2AP CD36 CD46 CDH1 CDKN1B CSF1R DLG4 DOK1 EPHB2 FASLG FLT1 FUNDC1 FXR2 GP6 ITGB4 JAK2 KDR KHDRBS1 KIT MST1R NEDD4 NIF3L1 NPHS1 OGT PAK2 PDCD6IP PDGFRB PECAM1 PTK2 PTPRE RASA1 RPL10 SLC9A3R1 SOCS3 SPRR2A SSBP3 THAP1 TNK2 TP53BP2 TRAF2 TRAF6 TRPV4 TYRO3 ZBTB8A ZNF512B
Entrez ID		139341	7525
HPRD ID		06658	01285
Ensembl ID		ENSG00000069509	ENSG00000176105
Uniprot IDs		Q8IVP5	P07947
PDB IDs			2HDA
Enriched GO Terms of Interacting Partners?		Nucleophagy Mitochondrion Degradation Organelle Disassembly Autophagic Vacuole Assembly Macroautophagy Cellular Response To Nitrogen Starvation Vacuole Organization Membrane Fusion Cellular Response To Starvation Autophagy Mitochondrion Organization Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus White Fat Cell Differentiation Response To Nutrient Levels Viral Genome Replication Response To Extracellular Stimulus Organelle Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Organelle Organization Cellular Metabolic Process Membrane Organization Fat Cell Differentiation Catabolic Process Response To External Stimulus Lamellipodium Morphogenesis Protein Desumoylation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Cellular Component Assembly Positive Regulation Of Chromatin Binding Negative Regulation Of Chromatin Binding Viral Life Cycle Negative Regulation Of Histone H4 Acetylation Regulation Of DNA Endoreduplication Early Endosome To Golgi Transport	Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Signal Transduction Positive Regulation Of Protein Metabolic Process Signaling Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Signaling Cell Communication Regulation Of Phosphatidylinositol 3-kinase Signaling Cell Surface Receptor Signaling Pathway Regulation Of Protein Metabolic Process Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Positive Regulation Of Signal Transduction Cellular Response To Stimulus Positive Regulation Of Intracellular Signal Transduction Immune System Process Peptidyl-tyrosine Phosphorylation Regulation Of Cellular Protein Metabolic Process Protein Autophosphorylation Positive Regulation Of Protein Modification Process Regulation Of Protein Phosphorylation Regulation Of Cellular Component Organization Innate Immune Response Response To Stimulus Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Phosphorylation Regulation Of Cellular Process Locomotion Intracellular Signal Transduction Immune Response Regulation Of Phosphorylation Positive Regulation Of Cell Proliferation Positive Regulation Of Metabolic Process Cell Differentiation Positive Regulation Of Phosphorylation Regulation Of Catalytic Activity Regulation Of Protein Kinase Activity Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component Regulation Of Immune System Process Regulation Of Kinase Activity Positive Regulation Of Cellular Metabolic Process Response To Stress Regulation Of Peptidyl-tyrosine Phosphorylation Cellular Response To Organic Substance System Development Regulation Of Cellular Component Movement Regulation Of Immune Response Positive Regulation Of Transferase Activity
Tagcloud ?		activates advances atg atg11 atg32 atg8 bnip3 bnip3l casein catabolic ck2 classic damaged dephosphorylates fccp homolog lc3 mammalian mammals mitochondria mitophagy nix notably pgam5 phosphorylate phosphorylates reversible unwanted yeast	answered antiapoptotic coculture defensive deregulated dramatic heat hyperthermia indicative indispensable insult mechanistically meiotic mta1 naturally negligible nonreceptor pachytene paracrine ps scs sertoli spermatocytes standpoint su6656 testicular testis thereafter varicocele
Tagcloud (Difference) ?		activates advances atg atg11 atg32 atg8 bnip3 bnip3l casein catabolic ck2 classic damaged dephosphorylates fccp homolog lc3 mammalian mammals mitochondria mitophagy nix notably pgam5 phosphorylate phosphorylates reversible unwanted yeast	answered antiapoptotic coculture defensive deregulated dramatic heat hyperthermia indicative indispensable insult mechanistically meiotic mta1 naturally negligible nonreceptor pachytene paracrine ps scs sertoli spermatocytes standpoint su6656 testicular testis thereafter varicocele
Tagcloud (Intersection) ?