FUNDC1 and SNX1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FUNDC1	SNX1
Gene Name		FUN14 domain containing 1	sorting nexin 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Outer Membrane Integral Component Of Mitochondrial Outer Membrane	Cytoplasm Golgi Apparatus Cytosol Endosome Membrane Membrane Extrinsic Component Of Membrane Lamellipodium Retromer Complex Early Endosome Membrane Intracellular Membrane-bounded Organelle Protein Complex
	Molecular Function	Protein Binding	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding Transferrin Receptor Binding Leptin Receptor Binding
	Biological Process	Mitochondrion Degradation Response To Hypoxia	Intracellular Protein Transport Vesicle Organization Receptor Internalization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Lamellipodium Morphogenesis
Pathways
Drugs
Diseases
GWAS		Personality dimensions ( 18957941)
Protein-Protein Interactions		14 interactors: CTBP1 CTBP2 EHHADH GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MTERF3 SENP2 SH3GLB1 SLC25A46 SNX1 TUFM YES1	25 interactors: ACVR1B ACVR2B AGTRAP APP ARFIP2 ARL6IP1 ATXN7 CMTM5 EGFR F2R FUNDC1 HGS INSR LEPR PDGFRB RABAC1 REEP6 RTN3 RTN4 SNX2 SNX32 SNX6 TK1 UFD1L VPS35
Entrez ID		139341	6642
HPRD ID		06658	03171
Ensembl ID		ENSG00000069509	ENSG00000028528
Uniprot IDs		Q8IVP5	Q13596
PDB IDs			2I4K 4FZS
Enriched GO Terms of Interacting Partners?		Nucleophagy Mitochondrion Degradation Organelle Disassembly Autophagic Vacuole Assembly Macroautophagy Cellular Response To Nitrogen Starvation Vacuole Organization Membrane Fusion Cellular Response To Starvation Autophagy Mitochondrion Organization Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus White Fat Cell Differentiation Response To Nutrient Levels Viral Genome Replication Response To Extracellular Stimulus Organelle Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Organelle Organization Cellular Metabolic Process Membrane Organization Fat Cell Differentiation Catabolic Process Response To External Stimulus Lamellipodium Morphogenesis Protein Desumoylation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Cellular Component Assembly Positive Regulation Of Chromatin Binding Negative Regulation Of Chromatin Binding Viral Life Cycle Negative Regulation Of Histone H4 Acetylation Regulation Of DNA Endoreduplication Early Endosome To Golgi Transport	Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Establishment Of Protein Localization Regulation Of Phosphorus Metabolic Process Regulation Of Kinase Activity Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Digestive System Development Negative Regulation Of ERBB Signaling Pathway Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cell Migration Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Positive Regulation Of Activin Receptor Signaling Pathway Endoplasmic Reticulum Tubular Network Organization Regulation Of Signal Transduction Regulation Of Cell Motility Retrograde Transport, Endosome To Golgi Protein Transport Regulation Of Locomotion Regulation Of Cellular Component Movement Endosomal Transport Regulation Of Peptidyl-tyrosine Phosphorylation Vesicle Organization Protein Localization Protein Autophosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Signaling Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Kinase Activity Cell Surface Receptor Signaling Pathway Positive Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Kinase Activity Regulation Of JAK-STAT Cascade Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Protein Metabolic Process Activation Of Protein Kinase Activity Regulation Of Protein Metabolic Process Positive Regulation Of Phosphorylation Signal Transduction By Phosphorylation Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Cycle Positive Regulation Of Transferase Activity Positive Regulation Of Protein Modification Process Intracellular Protein Transport Positive Regulation Of Mitotic Cell Cycle
Tagcloud ?		activates advances atg atg11 atg32 atg8 bnip3 bnip3l casein catabolic ck2 classic damaged dephosphorylates fccp homolog lc3 mammalian mammals mitochondria mitophagy nix notably pgam5 phosphorylate phosphorylates reversible unwanted yeast	apical auxin brassinosteroid bundle carrier clasp cytokinin cytoskeleton division edges efflux elongation endosomes fine maxima meristem microtubule microtubules modulates normally optimize pin2 prevailing sharp tethering transfacial transitions tunes works
Tagcloud (Difference) ?		activates advances atg atg11 atg32 atg8 bnip3 bnip3l casein catabolic ck2 classic damaged dephosphorylates fccp homolog lc3 mammalian mammals mitochondria mitophagy nix notably pgam5 phosphorylate phosphorylates reversible unwanted yeast	apical auxin brassinosteroid bundle carrier clasp cytokinin cytoskeleton division edges efflux elongation endosomes fine maxima meristem microtubule microtubules modulates normally optimize pin2 prevailing sharp tethering transfacial transitions tunes works
Tagcloud (Intersection) ?