YES1 and C1orf94

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		YES1	C1orf94
Gene Name		YES proto-oncogene 1, Src family tyrosine kinase	chromosome 1 open reading frame 94
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Microtubule Organizing Center Cytosol Actin Filament Plasma Membrane Focal Adhesion Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Receptor Binding Epidermal Growth Factor Receptor Binding Protein Binding ATP Binding Enzyme Binding Ion Channel Binding	Protein Binding
	Biological Process	Cellular Protein Modification Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Blood Coagulation Glucose Transport Cell Differentiation T Cell Costimulation Cellular Response To Platelet-derived Growth Factor Stimulus Peptidyl-tyrosine Autophosphorylation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Cell Proliferation Regulation Of Vascular Permeability Innate Immune Response Ephrin Receptor Signaling Pathway Leukocyte Migration Cellular Response To Peptide Hormone Stimulus
Pathways		Axon guidance Costimulation by the CD28 family EPHB-mediated forward signaling Signaling by SCF-KIT EPHA-mediated growth cone collapse Regulation of KIT signaling EPH-ephrin mediated repulsion of cells Regulation of signaling by CBL EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis FCGR activation Innate Immune System CTLA4 inhibitory signaling CD28 co-stimulation Cytokine Signaling in Immune system PECAM1 interactions Cell surface interactions at the vascular wall Signaling by ERBB2 Signaling by Interleukins Interleukin-3, 5 and GM-CSF signaling Adaptive Immune System
Drugs		Dasatinib
Diseases
GWAS		Pulmonary function in asthmatics ( 23541324)	Epilepsy (generalized) ( 22949513)
Protein-Protein Interactions		49 interactors: ADAM12 ADAM15 C1orf94 CBL CD2AP CD36 CD46 CDH1 CDKN1B CSF1R DLG4 DOK1 EPHB2 FASLG FLT1 FUNDC1 FXR2 GP6 ITGB4 JAK2 KDR KHDRBS1 KIT MST1R NEDD4 NIF3L1 NPHS1 OGT PAK2 PDCD6IP PDGFRB PECAM1 PTK2 PTPRE RASA1 RPL10 SLC9A3R1 SOCS3 SPRR2A SSBP3 THAP1 TNK2 TP53BP2 TRAF2 TRAF6 TRPV4 TYRO3 ZBTB8A ZNF512B	60 interactors: ACTN3 AES AKAP9 ATRIP ATXN1 BANP BOLA1 BOLL BYSL C1orf109 C6orf165 CARD9 CCHCR1 CCNJL CDKN2D DAB1 DAZAP2 DGCR6 DOK6 DTX2 FAM168A FAM46D GCC1 GORASP2 GRB2 GSE1 HNRNPF HOXA1 IPO11 KLHL32 LMO2 MAGED1 MAPK1IP1L MAPK9 MEIS2 MVP NFKBID NGB OAZ3 OIP5 PITX1 PLEKHB2 PRKAG1 PRR20A R3HDM2 RAD51D RBFOX1 RBFOX2 RBM47 RBPMS ROR2 SMAP2 TBX6 TNPO2 TXNDC9 UBQLN4 USO1 VENTX VPS37C YES1
Entrez ID		7525	84970
HPRD ID		01285	11310
Ensembl ID		ENSG00000176105	ENSG00000142698
Uniprot IDs		P07947	Q6P1W5
PDB IDs		2HDA
Enriched GO Terms of Interacting Partners?		Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Signal Transduction Positive Regulation Of Protein Metabolic Process Signaling Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Signaling Cell Communication Regulation Of Phosphatidylinositol 3-kinase Signaling Cell Surface Receptor Signaling Pathway Regulation Of Protein Metabolic Process Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Positive Regulation Of Signal Transduction Cellular Response To Stimulus Positive Regulation Of Intracellular Signal Transduction Immune System Process Peptidyl-tyrosine Phosphorylation Regulation Of Cellular Protein Metabolic Process Protein Autophosphorylation Positive Regulation Of Protein Modification Process Regulation Of Protein Phosphorylation Regulation Of Cellular Component Organization Innate Immune Response Response To Stimulus Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Phosphorylation Regulation Of Cellular Process Locomotion Intracellular Signal Transduction Immune Response Regulation Of Phosphorylation Positive Regulation Of Cell Proliferation Positive Regulation Of Metabolic Process Cell Differentiation Positive Regulation Of Phosphorylation Regulation Of Catalytic Activity Regulation Of Protein Kinase Activity Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component Regulation Of Immune System Process Regulation Of Kinase Activity Positive Regulation Of Cellular Metabolic Process Response To Stress Regulation Of Peptidyl-tyrosine Phosphorylation Cellular Response To Organic Substance System Development Regulation Of Cellular Component Movement Regulation Of Immune Response Positive Regulation Of Transferase Activity	Regulation Of Phosphorus Metabolic Process Regulation Of Phosphorylation Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Radial Glia Guided Migration Of Purkinje Cell Regulation Of Protein Metabolic Process Multicellular Organismal Development Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Phosphorylation Cell Cycle Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Developmental Process Positive Regulation Of Cellular Biosynthetic Process Anatomical Structure Arrangement Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Splicing Cell Migration In Hindbrain Regulation Of RNA Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phosphorylation Response To Radiation Negative Regulation Of Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cytoplasmic Transport Neuromuscular Process RNA Metabolic Process Positive Regulation Of Protein Metabolic Process Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Abducens Nerve Formation Optokinetic Behavior Regulation Of Erythrocyte Differentiation Response To Organic Substance Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Immune System Process Regulation Of Cellular Process Organ Development System Development Cell Differentiation Nucleobase-containing Compound Metabolic Process Regulation Of Kinase Activity Response To Light Stimulus Cellular Nitrogen Compound Metabolic Process Facial Nucleus Development Cerebellum Structural Organization Putrescine Transport Golgi Vesicle Docking
Tagcloud ?		answered antiapoptotic coculture defensive deregulated dramatic heat hyperthermia indicative indispensable insult mechanistically meiotic mta1 naturally negligible nonreceptor pachytene paracrine ps scs sertoli spermatocytes standpoint su6656 testicular testis thereafter varicocele
Tagcloud (Difference) ?		answered antiapoptotic coculture defensive deregulated dramatic heat hyperthermia indicative indispensable insult mechanistically meiotic mta1 naturally negligible nonreceptor pachytene paracrine ps scs sertoli spermatocytes standpoint su6656 testicular testis thereafter varicocele
Tagcloud (Intersection) ?