YES1 and SSBP3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		YES1	SSBP3
Gene Name		YES proto-oncogene 1, Src family tyrosine kinase	single stranded DNA binding protein 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Microtubule Organizing Center Cytosol Actin Filament Plasma Membrane Focal Adhesion Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Extracellular Vesicular Exosome	Nucleus Protein Complex
	Molecular Function	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Receptor Binding Epidermal Growth Factor Receptor Binding Protein Binding ATP Binding Enzyme Binding Ion Channel Binding	Single-stranded DNA Binding
	Biological Process	Cellular Protein Modification Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Blood Coagulation Glucose Transport Cell Differentiation T Cell Costimulation Cellular Response To Platelet-derived Growth Factor Stimulus Peptidyl-tyrosine Autophosphorylation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Cell Proliferation Regulation Of Vascular Permeability Innate Immune Response Ephrin Receptor Signaling Pathway Leukocyte Migration Cellular Response To Peptide Hormone Stimulus	Hematopoietic Progenitor Cell Differentiation Transcription, DNA-templated Protein Complex Assembly Positive Regulation Of Cell Proliferation Prechordal Plate Formation Midbrain-hindbrain Boundary Initiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Head Morphogenesis Positive Regulation Of Anterior Head Development
Pathways		Axon guidance Costimulation by the CD28 family EPHB-mediated forward signaling Signaling by SCF-KIT EPHA-mediated growth cone collapse Regulation of KIT signaling EPH-ephrin mediated repulsion of cells Regulation of signaling by CBL EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis FCGR activation Innate Immune System CTLA4 inhibitory signaling CD28 co-stimulation Cytokine Signaling in Immune system PECAM1 interactions Cell surface interactions at the vascular wall Signaling by ERBB2 Signaling by Interleukins Interleukin-3, 5 and GM-CSF signaling Adaptive Immune System
Drugs		Dasatinib
Diseases
GWAS		Pulmonary function in asthmatics ( 23541324)
Protein-Protein Interactions		49 interactors: ADAM12 ADAM15 C1orf94 CBL CD2AP CD36 CD46 CDH1 CDKN1B CSF1R DLG4 DOK1 EPHB2 FASLG FLT1 FUNDC1 FXR2 GP6 ITGB4 JAK2 KDR KHDRBS1 KIT MST1R NEDD4 NIF3L1 NPHS1 OGT PAK2 PDCD6IP PDGFRB PECAM1 PTK2 PTPRE RASA1 RPL10 SLC9A3R1 SOCS3 SPRR2A SSBP3 THAP1 TNK2 TP53BP2 TRAF2 TRAF6 TRPV4 TYRO3 ZBTB8A ZNF512B	16 interactors: ANKEF1 APP ARNT2 EWSR1 HCLS1 IL36RN LDB1 LDB2 LMX1B NXT2 PIN1 RFC1 SUPT5H TBC1D23 YES1 ZNF226
Entrez ID		7525	23648
HPRD ID		01285	09578
Ensembl ID		ENSG00000176105	ENSG00000157216
Uniprot IDs		P07947	Q9BWW4
PDB IDs		2HDA
Enriched GO Terms of Interacting Partners?		Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Signal Transduction Positive Regulation Of Protein Metabolic Process Signaling Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Signaling Cell Communication Regulation Of Phosphatidylinositol 3-kinase Signaling Cell Surface Receptor Signaling Pathway Regulation Of Protein Metabolic Process Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Positive Regulation Of Signal Transduction Cellular Response To Stimulus Positive Regulation Of Intracellular Signal Transduction Immune System Process Peptidyl-tyrosine Phosphorylation Regulation Of Cellular Protein Metabolic Process Protein Autophosphorylation Positive Regulation Of Protein Modification Process Regulation Of Protein Phosphorylation Regulation Of Cellular Component Organization Innate Immune Response Response To Stimulus Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Phosphorylation Regulation Of Cellular Process Locomotion Intracellular Signal Transduction Immune Response Regulation Of Phosphorylation Positive Regulation Of Cell Proliferation Positive Regulation Of Metabolic Process Cell Differentiation Positive Regulation Of Phosphorylation Regulation Of Catalytic Activity Regulation Of Protein Kinase Activity Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component Regulation Of Immune System Process Regulation Of Kinase Activity Positive Regulation Of Cellular Metabolic Process Response To Stress Regulation Of Peptidyl-tyrosine Phosphorylation Cellular Response To Organic Substance System Development Regulation Of Cellular Component Movement Regulation Of Immune Response Positive Regulation Of Transferase Activity	Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Epithelial Structure Maintenance Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Cerebellum Morphogenesis Gene Expression Regulation Of Cellular Process Regulation Of DNA-templated Transcription, Elongation Hindbrain Morphogenesis Histone H3-K4 Acetylation Negative Regulation Of Interferon-gamma Secretion Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Somatic Stem Cell Maintenance Brain Development Negative Regulation Of Cellular Metabolic Process Homeostatic Process Head Development Innate Immune Response Antifungal Humoral Response Synaptic Growth At Neuromuscular Junction Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Trabecular Meshwork Development Positive Regulation Of Hemoglobin Biosynthetic Process Hair Follicle Development Hair Cycle Process Collateral Sprouting In Absence Of Injury Regulation Of Interleukin-6 Production Hair Cycle Cerebellum Development Regulation Of Receptor Activity Central Nervous System Development Metencephalon Development Response To Organic Substance Collateral Sprouting Axon Midline Choice Point Recognition
Tagcloud ?		answered antiapoptotic coculture defensive deregulated dramatic heat hyperthermia indicative indispensable insult mechanistically meiotic mta1 naturally negligible nonreceptor pachytene paracrine ps scs sertoli spermatocytes standpoint su6656 testicular testis thereafter varicocele	applicable biogenesis btb btbd9 clones crlf3 detail easily elusive head legs microvesicles morphogenesis morphology nervous pc12 phenotypes pheochromocytoma poz restless slmvs stranded synaptic theoretically transport trapped uncovering vesicle vesicles
Tagcloud (Difference) ?		answered antiapoptotic coculture defensive deregulated dramatic heat hyperthermia indicative indispensable insult mechanistically meiotic mta1 naturally negligible nonreceptor pachytene paracrine ps scs sertoli spermatocytes standpoint su6656 testicular testis thereafter varicocele	applicable biogenesis btb btbd9 clones crlf3 detail easily elusive head legs microvesicles morphogenesis morphology nervous pc12 phenotypes pheochromocytoma poz restless slmvs stranded synaptic theoretically transport trapped uncovering vesicle vesicles
Tagcloud (Intersection) ?