CPNE4 and PDCD6

Number of citations of the paper that reports this interaction (PubMedID 12522145)
0

Data Source:
HPRD (two hybrid, in vitro)

		CPNE4	PDCD6
Description		copine 4	programmed cell death 6
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Synapse Extracellular Exosome Glutamatergic Synapse	Nucleus Nucleoplasm Cytoplasm Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Membrane COPII Vesicle Coat Cytoplasmic Vesicle Cul3-RING Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm Extracellular Exosome Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding Calcium-dependent Phospholipid Binding Metal Ion Binding	Magnesium Ion Binding Calcium Ion Binding Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Protein Homodimerization Activity Protein-membrane Adaptor Activity Metal Ion Binding Protein Heterodimerization Activity Protein Dimerization Activity Calcium-dependent Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Cellular Response To Calcium Ion	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Apoptotic Process Positive Regulation Of Endothelial Cell Migration Neural Crest Formation Neural Crest Cell Development Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of TOR Signaling Cellular Response To Heat Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Angiogenesis COPII Vesicle Coating Response To Calcium Ion Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Apoptotic Signaling Pathway Positive Regulation Of Protein Monoubiquitination
Pathways
Drugs			Calcium Zinc Calcium citrate Calcium Phosphate Calcium phosphate dihydrate Zinc acetate
Diseases
GWAS		Adult body size ( 32376654) Aggressiveness in attention deficit hyperactivity disorder ( 27021288) Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Amyotrophic lateral sclerosis ( 22959728) Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals ( 22959728) Body mass index ( 25673413 28892062 31453325) Body mass index variance ( 31453325) Body size at age 10 ( 32376654) Circulating leptin levels in high cardiovascular risk ( 31766143) Coronary artery aneurysm in Kawasaki disease ( 27171184) Eosinophilic esophagitis ( 34506852) HDL cholesterol levels ( 32203549) Intracranial aneurysm ( 29531279) Iron status biomarkers (total iron binding capacity) ( 28334935) Iron status biomarkers (transferrin saturation) ( 28334935) L1-L4 bone mineral density x serum urate levels interaction ( 34046847) Metabolic syndrome ( 31589552) Motion sickness ( 25628336) Neutrophil count ( 21507922) Retinitis pigmentosa ( 33514863)	Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		17 interacting genes: ACTB BCOR BICD1 CCDC22 CEP162 CPNE1 MAP2K1 MYCBP NECAB1 PDCD6 PITPNM2 PPP5C RDX SKIL SPTBN1 UBE2M UBE2O	29 interacting genes: ANXA11 ANXA7 BAG4 CDKN2A CEBPA CPNE1 CPNE2 CPNE4 DIAPH3 FAS FASLG FNDC3A HEBP2 IGFALS KLHL12 MAP3K5 MAPK1IP1L MIA2 PDCD6IP PEF1 PRR19 SARAF SEC31A SH3KBP1 SHISA4 TIMM22 UBC VPS37C YWHAQ
Entrez ID		131034	10016
HPRD ID		05017	03035
Ensembl ID		ENSG00000196353	ENSG00000249915
Uniprot IDs		B7Z370 Q4G168 Q96A23	A0A024QZ42 A0A087WZ38 O75340 Q53FC3
PDB IDs			2ZN8 2ZN9 2ZND 2ZNE 2ZRS 2ZRT 3AAJ 3AAK 3WXA 5GQQ
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Localization To Cell Periphery Cortical Cytoskeleton Nucleoplasm Cytoplasm Apical Protein Localization Structural Constituent Of Cytoskeleton Cytoskeleton Cytosol Negative Regulation Of Signal Transduction Regulation Of Signal Transduction Cellular Localization Negative Regulation Of Cell Communication Negative Regulation Of Signaling Protein-containing Complex Binding Regulation Of Intracellular Signal Transduction Mitogen-activated Protein Kinase Kinase Kinase Binding Regulation Of Receptor Localization To Synapse Regulation Of Early Endosome To Late Endosome Transport Actin Filament Capping Blastocyst Hatching Regulation Of Protein Localization To Membrane Tau Protein Binding Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Regulation Of Cell Communication Vesicle-mediated Transport Regulation Of Signaling Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Actin Filament Depolymerization Negative Regulation Of Tooth Mineralization BCOR Complex Negative Regulation Of Actin Filament Polymerization Regulation Of Actin Filament Depolymerization Cortical Actin Cytoskeleton Establishment Of Protein Localization To Plasma Membrane Regulation Of Cellular Localization Regulation Of Protein Localization Regulation Of Norepinephrine Uptake Negative Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Heat Shock Protein Binding Golgi Inheritance Central Nervous System Formation Golgi To Plasma Membrane Transport NEDD8 Conjugating Enzyme Activity Regulation Of Vesicle-mediated Transport Ubiquitin-protein Transferase Activity Glutamatergic Synapse Nucleus Transporter Regulator Activity	Response To Metal Ion Calcium-dependent Protein Binding Response To Calcium Ion Calcium-dependent Phospholipid Binding Extracellular Exosome COPII Vesicle Coat Endoplasmic Reticulum Exit Site Vesicle Membrane Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Neural Crest Formation Necroptotic Signaling Pathway Vesicle-mediated Transport Phosphatidylserine Binding ESCRT I Complex Vesicle Organization Cellular Response To Metal Ion Replicative Senescence Cellular Response To Calcium Ion Programmed Necrotic Cell Death Cellular Response To Tumor Necrosis Factor Viral Budding Via Host ESCRT Complex Membrane Organization COPII Vesicle Coating Cellular Localization Viral Budding Autophagy Lymphocyte Apoptotic Process T Cell Apoptotic Process NF-kappaB Binding Ligase Inhibitor Activity Response To Tumor Necrosis Factor RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Vesicle Cargo Loading Golgi Vesicle Transport TERT-RMRP Complex Template-free RNA Nucleotidyltransferase Positive Regulation Of Transdifferentiation RNA-directed RNA Polymerase Complex SiRNA Transcription Negative Regulation Of MRNA Modification Multivesicular Body Organization Multivesicular Body Assembly Stem Cell Development Neural Crest Cell Development Vesicle Coating Stereocilia Tip-link Density COPII-coated ER To Golgi Transport Vesicle Cytokinetic Process Apoptotic Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?