CPNE4 and UBE2O

Number of citations of the paper that reports this interaction (PMID 12522145)
20

Data Source:
HPRD (two hybrid, in vitro)

		CPNE4	UBE2O
Gene Name		copine IV	ubiquitin-conjugating enzyme E2O
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm
	Molecular Function		Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Poly(A) RNA Binding Ubiquitin Protein Ligase Activity
	Biological Process		Protein Monoubiquitination Positive Regulation Of BMP Signaling Pathway Retrograde Transport, Endosome To Golgi Protein K63-linked Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 22959728) Neutrophil count ( 21507922)
Protein-Protein Interactions		16 interactors: ACTB BCOR BICD1 CCDC22 CEP162 CPNE1 MAP2K1 MYCBP PDCD6 PITPNM2 PPP5C RDX SKIL SPTBN1 UBE2M UBE2O	8 interactors: APPL1 BAP1 CPNE1 CPNE2 CPNE4 RNF10 SHBG TRIM27
Entrez ID		131034	63893
HPRD ID		05017	10928
Ensembl ID		ENSG00000196353	ENSG00000175931
Uniprot IDs		Q96A23	Q9C0C9
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Enzyme Linked Receptor Protein Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Anatomical Structure Morphogenesis Protein Heterooligomerization Golgi To Plasma Membrane Transport Intracellular Transport Protein Monoubiquitination Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Actin Filament Capping Organelle Transport Along Microtubule Cell Projection Organization Regulation Of Proteinase Activated Receptor Activity Negative Regulation Of Histone H3-K36 Methylation Negative Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Actin Filament Depolymerization Positive Regulation Of Signal Transduction Regulation Of Cellular Component Organization Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Regulation Of Signal Transduction Establishment Of Localization In Cell Negative Regulation Of Tooth Mineralization Negative Regulation Of Phospholipase C Activity Negative Regulation Of Protein Polymerization Post-Golgi Vesicle-mediated Transport Positive Regulation Of Intracellular Signal Transduction Anatomical Structure Development Negative Regulation Of Protein Complex Disassembly Transport Cell Projection Morphogenesis Vesicle-mediated Transport Minus-end-directed Organelle Transport Along Microtubule Axon Guidance Cell Part Morphogenesis Regulation Of Signaling Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Protein Depolymerization Regulation Of Organelle Organization Regulation Of Golgi Inheritance Protein Oligomerization Regulation Of Protein Complex Disassembly Specification Of Axis Polarity Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Cellular Localization Negative Regulation Of Protein Complex Assembly Microtubule-based Transport Regulation Of Vascular Smooth Muscle Contraction Common-partner SMAD Protein Phosphorylation Negative Regulation Of Odontogenesis	Primary Spermatocyte Growth Protein Ubiquitination Protein Modification By Small Protein Conjugation Negative Regulation Of Interleukin-2 Secretion Histone H2A-K119 Monoubiquitination Negative Regulation Of Schwann Cell Proliferation Monoubiquitinated Histone H2A Deubiquitination Negative Regulation Of Calcium Ion Import Interferon-gamma Secretion
Tagcloud ?			c4a cascades coagulation complement conjugating cytoskeleton declaration electrospray epiretinal esi esr1 genego helsinki hplc idiopathic ierm ierms ionization kegg metacore metalloproteinase proteome proteomes remolding rp tenets top vitreous
Tagcloud (Difference) ?			c4a cascades coagulation complement conjugating cytoskeleton declaration electrospray epiretinal esi esr1 genego helsinki hplc idiopathic ierm ierms ionization kegg metacore metalloproteinase proteome proteomes remolding rp tenets top vitreous
Tagcloud (Intersection) ?