CPNE4 and CEP162

Number of citations of the paper that reports this interaction (PMID 12522145)
20

Data Source:
HPRD (in vitro, two hybrid)

		CPNE4	CEP162
Gene Name		copine IV	centrosomal protein 162kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Centrosome Centriole Spindle Cytosol Axonemal Microtubule
	Molecular Function		Protein Binding
	Biological Process		Organelle Organization Cilium Assembly
Pathways			Organelle biogenesis and maintenance Assembly of the primary cilium Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 22959728) Neutrophil count ( 21507922)
Protein-Protein Interactions		16 interactors: ACTB BCOR BICD1 CCDC22 CEP162 CPNE1 MAP2K1 MYCBP PDCD6 PITPNM2 PPP5C RDX SKIL SPTBN1 UBE2M UBE2O	6 interactors: CPNE4 KDM1A PRMT1 PRMT8 SPP1 YEATS4
Entrez ID		131034	22832
HPRD ID		05017	10796
Ensembl ID		ENSG00000196353	ENSG00000135315
Uniprot IDs		Q96A23	Q5TB80
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Enzyme Linked Receptor Protein Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Anatomical Structure Morphogenesis Protein Heterooligomerization Golgi To Plasma Membrane Transport Intracellular Transport Protein Monoubiquitination Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Actin Filament Capping Organelle Transport Along Microtubule Cell Projection Organization Regulation Of Proteinase Activated Receptor Activity Negative Regulation Of Histone H3-K36 Methylation Negative Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Actin Filament Depolymerization Positive Regulation Of Signal Transduction Regulation Of Cellular Component Organization Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Regulation Of Signal Transduction Establishment Of Localization In Cell Negative Regulation Of Tooth Mineralization Negative Regulation Of Phospholipase C Activity Negative Regulation Of Protein Polymerization Post-Golgi Vesicle-mediated Transport Positive Regulation Of Intracellular Signal Transduction Anatomical Structure Development Negative Regulation Of Protein Complex Disassembly Transport Cell Projection Morphogenesis Vesicle-mediated Transport Minus-end-directed Organelle Transport Along Microtubule Axon Guidance Cell Part Morphogenesis Regulation Of Signaling Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Protein Depolymerization Regulation Of Organelle Organization Regulation Of Golgi Inheritance Protein Oligomerization Regulation Of Protein Complex Disassembly Specification Of Axis Polarity Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Cellular Localization Negative Regulation Of Protein Complex Assembly Microtubule-based Transport Regulation Of Vascular Smooth Muscle Contraction Common-partner SMAD Protein Phosphorylation Negative Regulation Of Odontogenesis	Histone Modification Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Chromatin Modification Peptidyl-arginine N-methylation Histone H4-R3 Methylation Chromatin Organization Histone Arginine Methylation Peptidyl-arginine Methylation Regulation Of Megakaryocyte Differentiation Regulation Of Hematopoietic Progenitor Cell Differentiation Chromosome Organization Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Primitive Erythrocyte Differentiation Histone Methylation Regulation Of Protein Binding Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Protein Methylation Regulation Of Myeloid Cell Differentiation Peptidyl-amino Acid Modification Negative Regulation Of Megakaryocyte Differentiation Regulation Of Binding Negative Regulation Of Collateral Sprouting Organelle Organization Cellular Protein Modification Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Negative Regulation Of Axon Regeneration Histone H3-K4 Demethylation Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cell Differentiation Methylation Histone H2A Acetylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Bone Resorption Granulocyte Differentiation Regulation Of Axon Regeneration Negative Regulation Of Histone Methylation In Utero Embryonic Development Positive Regulation Of Erythrocyte Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Histone H3-K4 Methylation
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