CPNE4 and CEP162

Number of citations of the paper that reports this interaction (PubMedID 12522145)
0

Data Source:
HPRD (two hybrid, in vitro)

		CPNE4	CEP162
Description		copine 4	centrosomal protein 162
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Synapse Extracellular Exosome Glutamatergic Synapse	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Centriole Spindle Cytosol Cytoskeleton Microtubule Axonemal Microtubule Centriolar Satellite Ciliary Basal Body
	Molecular Function	Protein Binding Calcium-dependent Phospholipid Binding Metal Ion Binding	Protein Binding
	Biological Process	Cellular Response To Calcium Ion	Cell Projection Organization Cilium Assembly
Pathways			Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Adult body size ( 32376654) Aggressiveness in attention deficit hyperactivity disorder ( 27021288) Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Amyotrophic lateral sclerosis ( 22959728) Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals ( 22959728) Body mass index ( 25673413 28892062 31453325) Body mass index variance ( 31453325) Body size at age 10 ( 32376654) Circulating leptin levels in high cardiovascular risk ( 31766143) Coronary artery aneurysm in Kawasaki disease ( 27171184) Eosinophilic esophagitis ( 34506852) HDL cholesterol levels ( 32203549) Intracranial aneurysm ( 29531279) Iron status biomarkers (total iron binding capacity) ( 28334935) Iron status biomarkers (transferrin saturation) ( 28334935) L1-L4 bone mineral density x serum urate levels interaction ( 34046847) Metabolic syndrome ( 31589552) Motion sickness ( 25628336) Neutrophil count ( 21507922) Retinitis pigmentosa ( 33514863)	Diabetic retinopathy in type 2 diabetes ( 25364816)
Interacting Genes		17 interacting genes: ACTB BCOR BICD1 CCDC22 CEP162 CPNE1 MAP2K1 MYCBP NECAB1 PDCD6 PITPNM2 PPP5C RDX SKIL SPTBN1 UBE2M UBE2O	7 interacting genes: CPNE4 KDM1A MTDH PRMT1 PRMT8 SPP1 YEATS4
Entrez ID		131034	22832
HPRD ID		05017	10796
Ensembl ID		ENSG00000196353	ENSG00000135315
Uniprot IDs		B7Z370 Q4G168 Q96A23	Q5TB80
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Localization To Cell Periphery Cortical Cytoskeleton Nucleoplasm Cytoplasm Apical Protein Localization Structural Constituent Of Cytoskeleton Cytoskeleton Cytosol Negative Regulation Of Signal Transduction Regulation Of Signal Transduction Cellular Localization Negative Regulation Of Cell Communication Negative Regulation Of Signaling Protein-containing Complex Binding Regulation Of Intracellular Signal Transduction Mitogen-activated Protein Kinase Kinase Kinase Binding Regulation Of Receptor Localization To Synapse Regulation Of Early Endosome To Late Endosome Transport Actin Filament Capping Blastocyst Hatching Regulation Of Protein Localization To Membrane Tau Protein Binding Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Regulation Of Cell Communication Vesicle-mediated Transport Regulation Of Signaling Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Actin Filament Depolymerization Negative Regulation Of Tooth Mineralization BCOR Complex Negative Regulation Of Actin Filament Polymerization Regulation Of Actin Filament Depolymerization Cortical Actin Cytoskeleton Establishment Of Protein Localization To Plasma Membrane Regulation Of Cellular Localization Regulation Of Protein Localization Regulation Of Norepinephrine Uptake Negative Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Heat Shock Protein Binding Golgi Inheritance Central Nervous System Formation Golgi To Plasma Membrane Transport NEDD8 Conjugating Enzyme Activity Regulation Of Vesicle-mediated Transport Ubiquitin-protein Transferase Activity Glutamatergic Synapse Nucleus Transporter Regulator Activity	Protein-arginine Omega-N Monomethyltransferase Activity Peptidyl-arginine Methylation Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone H4 Methyltransferase Activity Regulation Of Double-strand Break Repair Via Homologous Recombination Protein-arginine N-methyltransferase Activity Regulation Of DNA Recombination Regulation Of Double-strand Break Repair Regulation Of Cellular Response To Stress S-adenosyl-L-methionine Binding Chromatin Remodeling Histone Methyltransferase Activity Protein Methylation Regulation Of DNA Repair Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Enzyme Binding Positive Regulation Of DNA Recombination Regulation Of RNA Metabolic Process GATOR1 Complex Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Double-strand Break Repair Regulation Of DNA Metabolic Process Positive Regulation Of Estradiol Secretion Histone H3K18ac Reader Activity Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Macromolecule Methylation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Estradiol Secretion Histone H3K27ac Reader Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of DNA Repair Regulation Of Multicellular Organismal Development Positive Regulation Of Biosynthetic Process Response To Nutrient N-methyltransferase Activity Protein Demethylase Activity Histone H4R3 Methyltransferase Activity Methyltransferase Activity Positive Regulation Of Hemoglobin Biosynthetic Process Androgen Catabolic Process MRF Binding Regulation Of Hemoglobin Biosynthetic Process Mitogen-activated Protein Kinase P38 Binding Response To Methionine
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