ZRSR2 and KHDC4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZRSR2	KHDC4
Description		zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2	KH domain containing 4, pre-mRNA splicing factor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex U2AF Complex Ribonucleoprotein Complex	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Pre-mRNA 3'-splice Site Binding Identical Protein Binding Metal Ion Binding	RNA Binding Protein Binding
	Biological Process	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	MRNA Splice Site Recognition MRNA Processing RNA Splicing
Pathways		mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS
Interacting Genes		23 interacting genes: APP CCNL1 CLK1 CLK2 DSCR9 DVL3 KHDC4 LUC7L2 PRPF6 REP15 RPS27L SDCBP2 SPATS2L SRPK2 SRRM4 SRSF1 SRSF2 SRSF5 SSX2IP TEPSIN TNFAIP8L1 U2AF1 U2AF2	21 interacting genes: BANP C14orf119 DNAJC5 KCNIP3 MAGEA12 NRF1 NUTF2 PIDD1 PRKAB2 PRR13 PSMB1 PUF60 QRICH1 RBM23 RBM39 RHOXF2 SAT1 SPANXN2 U2AF2 ZDHHC17 ZRSR2
Entrez ID		8233	22889
HPRD ID		02068	17198
Ensembl ID		ENSG00000169249	ENSG00000132680
Uniprot IDs		A0A8I5KSD0 Q15696	Q7Z7F0
PDB IDs			2YQR
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Splicing Nuclear Speck Protein-RNA Complex Assembly RNA Splicing MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing MRNA Metabolic Process MRNA Splice Site Recognition RNA Binding RNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Protein-containing Complex Assembly Spliceosomal Complex Regulation Of MRNA Metabolic Process Protein-containing Complex Organization RNA Splicing, Via Transesterification Reactions MRNA Binding RS Domain Binding Positive Regulation Of RNA Splicing Pre-mRNA 3'-splice Site Binding U2AF Complex Spliceosomal Complex Assembly RNA Metabolic Process Protein Kinase B Binding Cellular Component Assembly MRNA Splicing, Via Spliceosome Nucleus Catalytic Step 2 Spliceosome U2-type Prespliceosome Protein Serine/threonine/tyrosine Kinase Activity Liver Regeneration Neuron Maturation Nucleoplasm Nucleic Acid Binding Nucleic Acid Metabolic Process Frizzled Binding Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Glucose Transporter Complex Coated Vesicle Membrane	Pre-mRNA 3'-splice Site Binding U2AF Complex Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome U1 SnRNP Binding RNA Splicing Regulation Of RNA Splicing MRNA Processing Nucleus Nucleic Acid Binding Regulation Of MRNA Metabolic Process MRNA Metabolic Process Spermidine Binding Perforant Pathway To Dendrate Granule Cell Synapse Spermidine Acetylation Putrescine Catabolic Process MRNA Splicing, Via Spliceosome Spliceosomal Complex Assembly Protein-RNA Complex Assembly RNA Splicing, Via Transesterification Reactions Poly-pyrimidine Tract Binding Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Nucleoplasm RNA Processing Diamine N-acetyltransferase Activity Protein Localization To Nuclear Pore Endopeptidase Complex Identical Protein Binding
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