ZRSR2 and SRSF2

Number of citations of the paper that reports this interaction (PMID 9237760)
34

Data Source:
HPRD (two hybrid, in vitro)

		ZRSR2	SRSF2
Gene Name		zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2	serine/arginine-rich splicing factor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	U12-type Spliceosomal Complex	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm PML Body Nuclear Speck Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding	Nucleotide Binding Transcription Corepressor Activity Protein Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Negative Regulation Of Nucleic Acid-templated Transcription
Pathways			mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: APP CLK2 SDCBP2 SRPK1 SRPK2 SRSF1 SRSF2 SSX2IP U2AF1 U2AF2	33 interactors: ADAP1 BARD1 CCNL1 CCNL2 CDK12 CDK6 CEP72 CIR1 CSNK2A1 FUS GEMIN2 GOLGA2 KRT31 KRT40 LIG4 LZTS2 NCF1 PRCC SCAF11 SNRNP70 SREK1 SRSF1 SRSF11 SRSF3 SRSF4 TCF4 TRA2B TRIM27 U2AF1 UBQLN4 YTHDC1 ZRANB2 ZRSR2
Entrez ID		8233	6427
HPRD ID		02068	02888
Ensembl ID		ENSG00000169249	ENSG00000161547
Uniprot IDs		Q15696	Q01130 Q53FN0
PDB IDs			2KN4 2LEA 2LEB 2LEC
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA 3'-end Processing Regulation Of RNA Splicing MRNA Metabolic Process RNA 3'-end Processing RNA Processing Termination Of RNA Polymerase II Transcription RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Processing Nuclear Export MRNA Transport RNA Transport RNA Localization Intracellular Transport Nucleocytoplasmic Transport Establishment Of Localization In Cell Nuclear Transport Cellular Localization Positive Regulation Of Viral Genome Replication RNA Metabolic Process Gene Expression Cytoplasmic Transport Negative Regulation Of Viral Genome Replication Spliceosomal Complex Assembly Transcription From RNA Polymerase II Promoter Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Nuclear Speck Organization Negative Regulation Of Viral Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Synaptic Growth At Neuromuscular Junction Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transport Nucleus Organization Cellular Nitrogen Compound Metabolic Process Collateral Sprouting In Absence Of Injury Microtubule-based Transport Protein Phosphorylation Cytoskeleton-dependent Intracellular Transport Regulation Of Viral Process Collateral Sprouting	RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Termination Of RNA Polymerase II Transcription Nitrogen Compound Metabolic Process Nuclear Export Spliceosomal Complex Assembly MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus Nucleocytoplasmic Transport Nuclear Transport MRNA 3'-end Processing Regulation Of MRNA Processing RNA 3'-end Processing MRNA Transport RNA Transport Cellular Macromolecular Complex Assembly RNA Localization Regulation Of MRNA Splicing, Via Spliceosome Ribonucleoprotein Complex Assembly Cell Cycle Regulation Of RNA Splicing Regulation Of Cell Cycle Cytoplasmic Transport Cellular Metabolic Process Mitotic Cell Cycle Cell Cycle Process Ribonucleoprotein Complex Biogenesis Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Intracellular Transport RNA Biosynthetic Process Mitotic Cell Cycle Process Negative Regulation Of Cell Cycle Cellular Component Assembly Positive Regulation Of MRNA Splicing, Via Spliceosome DNA Strand Elongation Involved In DNA Replication Cellular Localization DNA Strand Elongation Regulation Of Protein Export From Nucleus
Tagcloud ?		bcl11b cadherin discovered dnm2 druggable exhibitedthe fat1 fbxw7 frequencies guide harboured herc1 jak jak3 lymphoblastic mll2 mutational notch1 notch2 phf6 recurrent regulators reln secretase splicing subclonal unfavourable warranted wt1	asxl1 biologic clonal cmml created cytopenias dependence discern dysplasia entity extramedullary extrapolation focuses granulocyte hematologic identifies landscape macrophage makes malignancy monocytosis myelomonocytic ontology propensity scientific speculative supporting tools troublesome
Tagcloud (Difference) ?		bcl11b cadherin discovered dnm2 druggable exhibitedthe fat1 fbxw7 frequencies guide harboured herc1 jak jak3 lymphoblastic mll2 mutational notch1 notch2 phf6 recurrent regulators reln secretase splicing subclonal unfavourable warranted wt1	asxl1 biologic clonal cmml created cytopenias dependence discern dysplasia entity extramedullary extrapolation focuses granulocyte hematologic identifies landscape macrophage makes malignancy monocytosis myelomonocytic ontology propensity scientific speculative supporting tools troublesome
Tagcloud (Intersection) ?