CLIC1 and NUP62

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CLIC1	NUP62
Gene Name		chloride intracellular channel 1	nucleoporin 62kDa
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Nuclear Envelope Cytoplasm Mitochondrion Plasma Membrane Brush Border Membrane Nuclear Membrane Vesicle Chloride Channel Complex Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Blood Microparticle	Spindle Pole Nuclear Envelope Nuclear Pore Cytoplasm Ribonucleoprotein Complex Nucleocytoplasmic Shuttling Complex Nuclear Membrane Intracellular Membrane-bounded Organelle Pore Complex
	Molecular Function	Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding	Chromatin Binding Nucleocytoplasmic Transporter Activity Protein Binding Structural Constituent Of Nuclear Pore Receptor Signaling Complex Scaffold Activity SH2 Domain Binding Ubiquitin Binding Thyroid Hormone Receptor Binding PTB Domain Binding
	Biological Process	Chloride Transport Signal Transduction Regulation Of Ion Transmembrane Transport Positive Regulation Of Osteoblast Differentiation Regulation Of Cell Cycle Regulation Of Mitochondrial Membrane Potential Platelet Aggregation Chloride Transmembrane Transport	Mitotic Cell Cycle Carbohydrate Metabolic Process Transcription, DNA-templated Nucleocytoplasmic Transport Mitotic Nuclear Envelope Disassembly Cell Surface Receptor Signaling Pathway Cell Aging Cell Death Negative Regulation Of Cell Proliferation Hexose Transport Pathogenesis Hormone-mediated Signaling Pathway Regulation Of Signal Transduction Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of MAP Kinase Activity Small Molecule Metabolic Process Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Regulation Of Ras Protein Signal Transduction Negative Regulation Of Ras Protein Signal Transduction MRNA Transport Transmembrane Transport
Pathways			Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: AKAP9 ALOX5AP ATP5F1 ATP6V0A1 ATP6V0C CPT1A IKBKG LSM1 MYOC NTF4 NUP62 PRDX4 PSMD10 RPLP1 SUMO4 THRA TRAPPC2 ZNF184 ZNF302	65 interactors: ABI2 ADAM15 AGR3 ATXN7 BFSP1 BLOC1S6 C1orf216 CCDC121 CCDC146 CCDC150 CCDC153 CCDC53 CCHCR1 CENPU CEP57L1 CLIC1 CRCT1 DDX3X DGCR6 DTNB FABP3 GOPC GORASP2 GTF2E2 HAUS1 HSF2 IFT20 IK IKBIP IPO5 ISCU KANSL1 KIFC3 KLHL32 KPNA1 KPNA2 KPNB1 KRT20 LMO2 MUC1 MYO15B NFX1 NUP153 NUP54 NUP98 NUPL1 NUTF2 NXF1 NXF2 OGT OIP5 PBX2 PHF21A PIN1 PTMA RANBP2 SMARCE1 SNAPC5 SP1 SSC5D THAP1 TRAF3 TXLNA XPO1 XPO6
Entrez ID		1192	23636
HPRD ID		04188	05782
Ensembl ID		ENSG00000213719	ENSG00000213024
Uniprot IDs		O00299 Q5SRT3	P37198
PDB IDs		1K0M 1K0N 1K0O 1RK4 3O3T 3P8W 3P90 3QR6 3SWL 3TGZ 3UVH 4IQA	2H4D
Enriched GO Terms of Interacting Partners?		Nitrogen Compound Metabolic Process Viral Process Cellular Nitrogen Compound Metabolic Process Cytoplasmic Sequestering Of Transcription Factor Gene Expression Cytoplasmic Sequestering Of Protein Cellular Metabolic Process Negative Regulation Of Intracellular Signal Transduction Cellular Localization Heterocycle Metabolic Process Transferrin Transport ATP Synthesis Coupled Proton Transport Hydrogen Ion Transmembrane Transport ATP Biosynthetic Process Phagosome Maturation Proton Transport Negative Regulation Of Transcription Factor Import Into Nucleus Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Lipid Catabolic Process Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Male Germ Cell Proliferation Skeletal Muscle Hypertrophy ERBB2-ERBB3 Signaling Pathway Sensory Organ Boundary Specification Negative Regulation Of Small GTPase Mediated Signal Transduction I-kappaB Kinase/NF-kappaB Signaling Cellular Response To Hormone Stimulus Nucleobase-containing Compound Metabolic Process ATP Hydrolysis Coupled Proton Transport Regulation Of MAPK Cascade Cellular Response To Stimulus Negative Regulation Of Protein Import Into Nucleus Small Molecule Metabolic Process Cellular Aromatic Compound Metabolic Process Monovalent Inorganic Cation Transport Purine Ribonucleoside Monophosphate Biosynthetic Process Biosynthetic Process RNA Biosynthetic Process Taste Bud Development ERBB2 Signaling Pathway Ganglion Mother Cell Fate Determination Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Protein Localization To Nucleus RNA Metabolic Process Iron Ion Transport Cellular Iron Ion Homeostasis Nucleoside Triphosphate Biosynthetic Process Negative Regulation Of Intracellular Protein Transport Regulation Of Transcription Factor Import Into Nucleus	Nucleocytoplasmic Transport Nuclear Transport Viral Process Cytoplasmic Transport MRNA Transport RNA Transport RNA Localization Intracellular Transport Nuclear Import Nucleus Organization Viral Life Cycle NLS-bearing Protein Import Into Nucleus Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Establishment Of Localization In Cell Protein Transport Protein Localization To Nucleus Cytokine-mediated Signaling Pathway Establishment Of Protein Localization Nuclear Export Cellular Localization Protein Import Into Nucleus Protein Export From Nucleus Intracellular Transport Of Virus Nuclear Envelope Organization Glucose Transport Protein Localization Cellular Response To Cytokine Stimulus Organelle Organization Protein Import Mitotic Cell Cycle Hexose Transport Cellular Protein Localization Viral Transcription Regulation Of Glucose Transport Response To Cytokine RNA Biosynthetic Process Intracellular Protein Transport Cell Cycle Carbohydrate Transport Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Cellular Response To Organic Substance Protein Localization To Organelle Gene Expression Response To Organic Substance Protein Targeting Nuclear Pore Complex Assembly Pathogenesis Establishment Of Protein Localization To Organelle Ribosomal Protein Import Into Nucleus
Tagcloud ?		aava accelerates atpase consolidating deregulated eevd endogenously enough gankyrin hek hot hub integrating interfaces mb mda migratory mutagenesis networks oncogenic oncoprotein pdb polypharmacological proteasome reflecting rescue searching silenced spot	barr bblf2 bblf4 betaherpesviruses bglf4 bslf1 cotransfected dilation ebv egress epstein fg gammaherpesviruses gateways import importin lytic mpm nls nlss nucleocapsids nucleocytoplasmic nucleoporins nup153 nups pore reorganization replicating vca
Tagcloud (Difference) ?		aava accelerates atpase consolidating deregulated eevd endogenously enough gankyrin hek hot hub integrating interfaces mb mda migratory mutagenesis networks oncogenic oncoprotein pdb polypharmacological proteasome reflecting rescue searching silenced spot	barr bblf2 bblf4 betaherpesviruses bglf4 bslf1 cotransfected dilation ebv egress epstein fg gammaherpesviruses gateways import importin lytic mpm nls nlss nucleocapsids nucleocytoplasmic nucleoporins nup153 nups pore reorganization replicating vca
Tagcloud (Intersection) ?