CLIC1 and NTF4

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CLIC1	NTF4
Gene Name		chloride intracellular channel 1	neurotrophin 4
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Nuclear Envelope Cytoplasm Mitochondrion Plasma Membrane Brush Border Membrane Nuclear Membrane Vesicle Chloride Channel Complex Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Blood Microparticle	Extracellular Region Endoplasmic Reticulum Lumen Cytoplasmic Membrane-bounded Vesicle
	Molecular Function	Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding	Neurotrophin P75 Receptor Binding Growth Factor Activity
	Biological Process	Chloride Transport Signal Transduction Regulation Of Ion Transmembrane Transport Positive Regulation Of Osteoblast Differentiation Regulation Of Cell Cycle Regulation Of Mitochondrial Membrane Potential Platelet Aggregation Chloride Transmembrane Transport	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell-cell Signaling Ganglion Mother Cell Fate Determination Long-term Memory Sensory Organ Boundary Specification Adult Locomotory Behavior Epidermis Development Mechanoreceptor Differentiation Negative Regulation Of Neuron Apoptotic Process Regulation Of Neuron Differentiation Neuron Projection Morphogenesis Innervation Taste Bud Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: AKAP9 ALOX5AP ATP5F1 ATP6V0A1 ATP6V0C CPT1A IKBKG LSM1 MYOC NTF4 NUP62 PRDX4 PSMD10 RPLP1 SUMO4 THRA TRAPPC2 ZNF184 ZNF302	4 interactors: ADAMTSL4 CLIC1 NGFR NTRK2
Entrez ID		1192	4909
HPRD ID		04188	01220
Ensembl ID		ENSG00000213719	ENSG00000225950
Uniprot IDs		O00299 Q5SRT3	P34130
PDB IDs		1K0M 1K0N 1K0O 1RK4 3O3T 3P8W 3P90 3QR6 3SWL 3TGZ 3UVH 4IQA	1B8M 1B98 1HCF
Enriched GO Terms of Interacting Partners?		Nitrogen Compound Metabolic Process Viral Process Cellular Nitrogen Compound Metabolic Process Cytoplasmic Sequestering Of Transcription Factor Gene Expression Cytoplasmic Sequestering Of Protein Cellular Metabolic Process Negative Regulation Of Intracellular Signal Transduction Cellular Localization Heterocycle Metabolic Process Transferrin Transport ATP Synthesis Coupled Proton Transport Hydrogen Ion Transmembrane Transport ATP Biosynthetic Process Phagosome Maturation Proton Transport Negative Regulation Of Transcription Factor Import Into Nucleus Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Lipid Catabolic Process Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Male Germ Cell Proliferation Skeletal Muscle Hypertrophy ERBB2-ERBB3 Signaling Pathway Sensory Organ Boundary Specification Negative Regulation Of Small GTPase Mediated Signal Transduction I-kappaB Kinase/NF-kappaB Signaling Cellular Response To Hormone Stimulus Nucleobase-containing Compound Metabolic Process ATP Hydrolysis Coupled Proton Transport Regulation Of MAPK Cascade Cellular Response To Stimulus Negative Regulation Of Protein Import Into Nucleus Small Molecule Metabolic Process Cellular Aromatic Compound Metabolic Process Monovalent Inorganic Cation Transport Purine Ribonucleoside Monophosphate Biosynthetic Process Biosynthetic Process RNA Biosynthetic Process Taste Bud Development ERBB2 Signaling Pathway Ganglion Mother Cell Fate Determination Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Protein Localization To Nucleus RNA Metabolic Process Iron Ion Transport Cellular Iron Ion Homeostasis Nucleoside Triphosphate Biosynthetic Process Negative Regulation Of Intracellular Protein Transport Regulation Of Transcription Factor Import Into Nucleus	Positive Regulation Of Axonogenesis Positive Regulation Of Cell Differentiation Regulation Of Axonogenesis Positive Regulation Of Cell Morphogenesis Involved In Differentiation Circadian Rhythm Negative Regulation Of Hair Follicle Development Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Neurotrophin Signaling Pathway Brain-derived Neurotrophic Factor Receptor Signaling Pathway Negative Regulation Of Hair Cycle Positive Regulation Of Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Cell Projection Organization Regulation Of Apoptotic Process Rhythmic Process Regulation Of Cell Death Regulation Of Cell Differentiation Positive Regulation Of Neuron Differentiation Regulation Of Neuron Projection Development Positive Regulation Of Neurogenesis Protein O-linked Fucosylation Positive Regulation Of Odontogenesis Retinal Rod Cell Development Peripheral Nervous System Neuron Development Calcium-mediated Signaling Using Intracellular Calcium Source Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Negative Regulation Of Anoikis Positive Regulation Of Cell Development Regulation Of Odontogenesis Of Dentin-containing Tooth Membrane Protein Intracellular Domain Proteolysis Regulation Of Hair Follicle Development Regulation Of Anoikis Regulation Of Neuron Differentiation Response To Auditory Stimulus Cellular Response To Growth Factor Stimulus Regulation Of Glucose Import In Response To Insulin Stimulus Positive Regulation Of Apoptotic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Programmed Cell Death Response To Growth Factor Regulation Of Hair Cycle Regulation Of Rac GTPase Activity Positive Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of Cell Death Glutamate Secretion Cellular Response To Nerve Growth Factor Stimulus Anion Transport Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Detection Of Temperature Stimulus
Tagcloud ?		aava accelerates atpase consolidating deregulated eevd endogenously enough gankyrin hek hot hub integrating interfaces mb mda migratory mutagenesis networks oncogenic oncoprotein pdb polypharmacological proteasome reflecting rescue searching silenced spot	actin contain cytosolic exclusively filament fractionation germination kim map mature motif mutagenesis ntmek2 ntprof2 p45 pellet phosphorylate pollen predominantly profilin profilins residue sipk speed substrates thought threonine tobacco tube
Tagcloud (Difference) ?		aava accelerates atpase consolidating deregulated eevd endogenously enough gankyrin hek hot hub integrating interfaces mb mda migratory networks oncogenic oncoprotein pdb polypharmacological proteasome reflecting rescue searching silenced spot	actin contain cytosolic exclusively filament fractionation germination kim map mature motif ntmek2 ntprof2 p45 pellet phosphorylate pollen predominantly profilin profilins residue sipk speed substrates thought threonine tobacco tube
Tagcloud (Intersection) ?		mutagenesis