CLIC1 and PSMD10

Number of citations of the paper that reports this interaction (PubMedID 24338975)
0

Data Source:
BioGRID (pull down)

		CLIC1	PSMD10
Description		chloride intracellular channel 1	proteasome 26S subunit, non-ATPase 10
Image
GO Annotations	Cellular Component	Extracellular Space Nucleus Nuclear Envelope Cytoplasm Mitochondrion Endoplasmic Reticulum Plasma Membrane Brush Border Membrane Nuclear Membrane Vesicle Monoatomic Ion Channel Complex Chloride Channel Complex Perinuclear Region Of Cytoplasm Extracellular Exosome Blood Microparticle	Proteasome Complex Nucleus Cytoplasm Cytosol Cytoskeleton Cilium Proteasome Regulatory Particle, Base Subcomplex Microtubule Cytoskeleton
	Molecular Function	Chloride Channel Activity Protein Binding Oxidoreductase Activity Cadherin Binding	Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Monoatomic Ion Transport Chloride Transport Signal Transduction Monoatomic Ion Transmembrane Transport Positive Regulation Of Osteoblast Differentiation Regulation Of Mitochondrial Membrane Potential Platelet Aggregation Chloride Transmembrane Transport	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Apoptotic Process Positive Regulation Of Cell Growth Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of MAPK Cascade Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Proteasome Regulatory Particle Assembly Negative Regulation Of Release Of Cytochrome C From Mitochondria
Pathways			Proteasome assembly Proteasome assembly
Drugs		Copper Artenimol
Diseases
GWAS		Adult body size ( 32376654) Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Inflammatory bowel disease ( 28067908) Mean platelet volume ( 27863252) Ulcerative colitis ( 28067908)
Interacting Genes		25 interacting genes: AKAP9 ALOX5AP ANXA1 ATP5PB ATP6V0A1 ATP6V0C CEBPA CFTR CPT1A IKBKG LSM1 MEOX2 MYOC NHSL2 NTF4 NUP62 PRDX4 PSMD10 RPLP1 SUMO4 THRA TPRN TRAPPC2 ZNF184 ZNF302	17 interacting genes: AGTR1 CCND2 CDK4 CEBPA CLIC1 GRSF1 HSPA4 LDB1 MAGEA4 MDM2 NCK2 NFKB1 PSAT1 PSMC4 RB1 RELA UBC
Entrez ID		1192	5716
HPRD ID		04188	04594
Ensembl ID		ENSG00000213719	ENSG00000101843
Uniprot IDs		O00299 Q53FB0 Q5SRT3	O75832
PDB IDs		1K0M 1K0N 1K0O 1RK4 3O3T 3P8W 3P90 3QR6 3SWL 3TGZ 3UVH 4IQA 4JZQ 4K0G 4K0N 7F8R 7FBQ	1QYM 1TR4 1UOH 4NIK 5VHF 5VHH 5VHI 5VHJ 5VHM 5VHN 5VHO 5VHP 5VHQ 5VHR 7VO6 7VXV 7VXW 7VY4 7VY7
Enriched GO Terms of Interacting Partners?			Transcription Regulator Complex NF-kappaB P50/p65 Complex Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Mitotic Cell Cycle Phase Transition Cyclin D2-CDK4 Complex Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Mitotic Cell Cycle Response To Xenobiotic Stimulus Rb-E2F Complex Positive Regulation Of Cell Differentiation Positive Regulation Of Cell Cycle Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Binding Cellular Response To Peptide Hormone Stimulus Cellular Response To Nicotine Regulation Of Inflammatory Response Chromatin Negative Regulation Of Nucleobase-containing Compound Metabolic Process DNA-templated Transcription Regulation Of Cell Differentiation Response To Vitamin Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Regulation Of DNA-templated Transcription Initiation Regulation Of Cell Population Proliferation Actinin Binding Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cell Cycle Process Cellular Response To Angiotensin Cellular Response To Interleukin-6 Negative Regulation Of Apoptotic Process Cellular Response To Tumor Necrosis Factor Negative Regulation Of Programmed Cell Death Positive Regulation Of Developmental Process Positive Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Cell Population Proliferation Response To Interleukin-6 Positive Regulation Of Proteasomal Protein Catabolic Process Ubiquitin Protein Ligase Binding Regulation Of Transcription By RNA Polymerase II Response To Peptide Hormone Response To Ether Response To Tumor Necrosis Factor Regulation Of Apoptotic Process Nucleoplasm Regulation Of Programmed Cell Death Regulation Of Mitotic Cell Cycle Phase Transition Histone Deacetylase Binding
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