CLIC1 and ZNF302

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		CLIC1	ZNF302
Description		chloride intracellular channel 1	zinc finger protein 302
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Nuclear Envelope Cytoplasm Mitochondrion Endoplasmic Reticulum Plasma Membrane Brush Border Membrane Nuclear Membrane Vesicle Monoatomic Ion Channel Complex Chloride Channel Complex Perinuclear Region Of Cytoplasm Extracellular Exosome Blood Microparticle	Nucleus
	Molecular Function	Chloride Channel Activity Protein Binding Oxidoreductase Activity Cadherin Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Monoatomic Ion Transport Chloride Transport Signal Transduction Monoatomic Ion Transmembrane Transport Positive Regulation Of Osteoblast Differentiation Regulation Of Mitochondrial Membrane Potential Platelet Aggregation Chloride Transmembrane Transport	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs		Copper Artenimol
Diseases
GWAS		Adult body size ( 32376654) Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Inflammatory bowel disease ( 28067908) Mean platelet volume ( 27863252) Ulcerative colitis ( 28067908)
Interacting Genes		25 interacting genes: AKAP9 ALOX5AP ANXA1 ATP5PB ATP6V0A1 ATP6V0C CEBPA CFTR CPT1A IKBKG LSM1 MEOX2 MYOC NHSL2 NTF4 NUP62 PRDX4 PSMD10 RPLP1 SUMO4 THRA TPRN TRAPPC2 ZNF184 ZNF302	11 interacting genes: APP CEP70 CLIC1 HGS KRTAP10-6 OPTN RBM11 TMEM132D TP53 TRIM55 TRIM63
Entrez ID		1192	55900
HPRD ID		04188	15765
Ensembl ID		ENSG00000213719	ENSG00000089335
Uniprot IDs		O00299 Q53FB0 Q5SRT3	A0A087WYF4 B3KY96 B4DMN2 D6R9Q0 E7EVR1 Q8NC84 Q9NR11
PDB IDs		1K0M 1K0N 1K0O 1RK4 3O3T 3P8W 3P90 3QR6 3SWL 3TGZ 3UVH 4IQA 4JZQ 4K0G 4K0N 7F8R 7FBQ
Enriched GO Terms of Interacting Partners?			Regulation Of Carbohydrate Catabolic Process Regulation Of Purine Nucleotide Metabolic Process Molecular Function Activator Activity Regulation Of Generation Of Precursor Metabolites And Energy Macroautophagy Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Innate Immune Response Regulation Of Phosphorus Metabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Mitophagy Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Reactive Oxygen Species Metabolic Process Autophagy Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding PTB Domain Binding Response To Interleukin-1 Regulation Of ATP Metabolic Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Defense Response To Symbiont Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Neuron Apoptotic Process Regulation Of MiRNA Transcription Defense Response To Other Organism Regulation Of MiRNA Metabolic Process Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Small Molecule Metabolic Process Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Defense Response To Gram-negative Bacterium Positive Regulation Of G Protein-coupled Receptor Internalization Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Negative Regulation Of Pentose-phosphate Shunt Oxidative Stress-induced Premature Senescence Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate
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