POLR3C

Gene Name		polymerase (RNA) III (DNA directed) polypeptide C (62kD)
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm DNA-directed RNA Polymerase III Complex Cytosol
	Molecular Function	RNA Polymerase III Activity DNA Binding DNA-directed RNA Polymerase Activity
	Biological Process	Regulation Of Transcription From RNA Polymerase III Promoter Transcription From RNA Polymerase III Promoter Transcription Elongation From RNA Polymerase III Promoter Termination Of RNA Polymerase III Transcription Gene Expression Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus
Pathways		RNA Polymerase III Transcription Termination RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Initiation From Type 2 Promoter Innate Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		8 interactors: APP CEP63 GTF3C4 PNMA5 ROCK1 ROPN1 TNR TRIM27
Entrez ID		10623
HPRD ID		17880
Ensembl ID		ENSG00000186141
Uniprot IDs		Q9BUI4
PDB IDs		2XUB 2XV4
Enriched GO Terms of Interacting Partners?		Axon Guidance Neuromuscular Process Controlling Balance Associative Learning Negative Regulation Of Axon Extension Involved In Regeneration Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Neuromuscular Process Neuron Projection Morphogenesis Learning Collateral Sprouting In Absence Of Injury Cell Morphogenesis Involved In Differentiation Synapse Organization Cellular Component Assembly Neuron Projection Development Negative Regulation Of Neuron Differentiation Collateral Sprouting Axon Midline Choice Point Recognition Membrane To Membrane Docking Cell Projection Morphogenesis Cell Part Morphogenesis 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Calcium Ion Import Apical Constriction Axon Choice Point Recognition TRNA Transcription Locomotory Behavior Neuron Development Negative Regulation Of Axon Regeneration Positive Regulation Of Transmission Of Nerve Impulse Interferon-gamma Secretion Learning Or Memory Neuron Remodeling Cell Morphogenesis Bleb Assembly Regulation Of Developmental Growth Negative Regulation Of Neurogenesis Cognition Cytoskeleton Organization Neuron Differentiation Cell Projection Organization Regulation Of Transmission Of Nerve Impulse Centriole Replication Locomotory Exploration Behavior Positive Regulation Of Cellular Component Biogenesis
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