POLR3C and CEP44

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		POLR3C	CEP44
Description		RNA polymerase III subunit C	centrosomal protein 44
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GO Annotations	Cellular Component	DNA-directed RNA Polymerase Complex Nucleus Nucleoplasm RNA Polymerase III Complex Cytosol	Spindle Pole Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Midbody Ciliary Basal Body
	Molecular Function	DNA Binding Single-stranded DNA Binding DNA-directed RNA Polymerase Activity Protein Binding	Protein Binding Microtubule Binding
	Biological Process	Immune System Process DNA-templated Transcription Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus	Centrosome Cycle Centriole Replication Centriole-centriole Cohesion
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS
Interacting Genes		38 interacting genes: ANKRD23 APP CAMK2B CEP44 CEP63 COIL DISC1 ENKD1 GOLGA2 GTF3C4 HAUS1 INCA1 KATNBL1 KIAA0408 KLHL2 KPNA1 KPNA3 KPNA5 KPNA6 KRT75 LZTS1 NCKIPSD OGT PAX6 PICK1 PNMA5 POU6F2 PRDM16 RBBP8NL ROCK1 ROPN1 SP100 TNR TRAF2 TRIM27 UBXN1 VAX1 VRTN	55 interacting genes: ABI2 ABI3 ANKRD11 AQP1 BEND7 BFSP2 BLOC1S6 BYSL CAB39 CBY2 CCDC116 CCDC146 CCDC185 CDC23 CENPP CEP57L1 CHIC2 DCTN2 DHX57 DIP2A ERAL1 FAM161A FAM74A4 FXR2 GNG11 H2AP HAUS1 ING5 KIAA0930 LINC02363 LMO1 LRRFIP1 MAPK9 MCRS1 MLLT6 MRFAP1L1 NAA10 PLEKHF2 POC1B POLR3C POP5 PSMD3 RBM15 RECK RNF8 SCNM1 TCEA2 TRIM41 TSGA10 TXLNA ZFYVE26 ZNF250 ZNF417 ZNF587 ZNF688
Entrez ID		10623	80817
HPRD ID		17880	13885
Ensembl ID		ENSG00000186141	ENSG00000164118
Uniprot IDs		Q9BUI4	Q9C0F1
PDB IDs		2XUB 2XV4 5AFQ 7A6H 7AE1 7AE3 7AEA 7AST 7D58 7D59 7DN3 7DU2 7FJI 7FJJ 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS	7PT5
Enriched GO Terms of Interacting Partners?		NLS-dependent Protein Nuclear Import Complex Nuclear Import Signal Receptor Activity Nuclear Localization Sequence Binding NLS-bearing Protein Import Into Nucleus Spindle Pole Regulation Of Synapse Organization Microtubule-based Process Regulation Of Postsynapse Organization Negative Regulation Of Catabolic Process Regulation Of Synapse Maturation Viral Penetration Into Host Nucleus Microtubule Organizing Center Organization Cytoskeleton Organization Microtubule Cytoskeleton Organization Identical Protein Binding Protein Localization To Organelle Regulation Of Synaptic Plasticity Plasma Membrane Bounded Cell Projection Organization Intracellular Transport Of Virus Regulation Of Neuroblast Proliferation Protein Import Into Nucleus Cytoplasm Centrosome Cycle Import Into Nucleus Host Cell Regulation Of Supramolecular Fiber Organization Cytoskeleton Postsynaptic Density Nucleoplasm Regulation Of Cell Junction Assembly Central Nervous System Development Membraneless Organelle Assembly Negative Regulation Of Neuroblast Proliferation Arp2/3 Complex Binding Regulation Of Synapse Assembly Centriole Cell Projection Organization Regulation Of Cellular Component Organization Negative Regulation Of Viral Transcription Negative Regulation Of Protein Ubiquitination Cytosol Organelle Organization Protein Localization To Nucleus Modulation Of Chemical Synaptic Transmission Positive Regulation Of Multicellular Organismal Process Regulation Of Amyloid-beta Clearance Organelle Assembly Regulation Of Viral Transcription TOR Signaling Chromatin DNA Binding
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