POLR3C and RBBP8NL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		POLR3C	RBBP8NL
Description		RNA polymerase III subunit C	RBBP8 N-terminal like
Image			No pdb structure
GO Annotations	Cellular Component	DNA-directed RNA Polymerase Complex Nucleus Nucleoplasm RNA Polymerase III Complex Cytosol	Extracellular Space
	Molecular Function	DNA Binding Single-stranded DNA Binding DNA-directed RNA Polymerase Activity Protein Binding	Protein Binding
	Biological Process	Immune System Process DNA-templated Transcription Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS
Interacting Genes		38 interacting genes: ANKRD23 APP CAMK2B CEP44 CEP63 COIL DISC1 ENKD1 GOLGA2 GTF3C4 HAUS1 INCA1 KATNBL1 KIAA0408 KLHL2 KPNA1 KPNA3 KPNA5 KPNA6 KRT75 LZTS1 NCKIPSD OGT PAX6 PICK1 PNMA5 POU6F2 PRDM16 RBBP8NL ROCK1 ROPN1 SP100 TNR TRAF2 TRIM27 UBXN1 VAX1 VRTN	9 interacting genes: ARPC3 CHIA CTBP2 EGLN3 LARP1B NCK2 PHF1 PIN1 POLR3C
Entrez ID		10623	140893
HPRD ID		17880	12751
Ensembl ID		ENSG00000186141	ENSG00000130701
Uniprot IDs		Q9BUI4	Q8NC74
PDB IDs		2XUB 2XV4 5AFQ 7A6H 7AE1 7AE3 7AEA 7AST 7D58 7D59 7DN3 7DU2 7FJI 7FJJ 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS
Enriched GO Terms of Interacting Partners?		NLS-dependent Protein Nuclear Import Complex Nuclear Import Signal Receptor Activity Nuclear Localization Sequence Binding NLS-bearing Protein Import Into Nucleus Spindle Pole Regulation Of Synapse Organization Microtubule-based Process Regulation Of Postsynapse Organization Negative Regulation Of Catabolic Process Regulation Of Synapse Maturation Viral Penetration Into Host Nucleus Microtubule Organizing Center Organization Cytoskeleton Organization Microtubule Cytoskeleton Organization Identical Protein Binding Protein Localization To Organelle Regulation Of Synaptic Plasticity Plasma Membrane Bounded Cell Projection Organization Intracellular Transport Of Virus Regulation Of Neuroblast Proliferation Protein Import Into Nucleus Cytoplasm Centrosome Cycle Import Into Nucleus Host Cell Regulation Of Supramolecular Fiber Organization Cytoskeleton Postsynaptic Density Nucleoplasm Regulation Of Cell Junction Assembly Central Nervous System Development Membraneless Organelle Assembly Negative Regulation Of Neuroblast Proliferation Arp2/3 Complex Binding Regulation Of Synapse Assembly Centriole Cell Projection Organization Regulation Of Cellular Component Organization Negative Regulation Of Viral Transcription Negative Regulation Of Protein Ubiquitination Cytosol Organelle Organization Protein Localization To Nucleus Modulation Of Chemical Synaptic Transmission Positive Regulation Of Multicellular Organismal Process Regulation Of Amyloid-beta Clearance Organelle Assembly Regulation Of Viral Transcription TOR Signaling Chromatin DNA Binding	Positive Regulation Of Biosynthetic Process Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Transcription Corepressor Binding Site Of Double-strand Break Response To Stress Cellular Response To Decreased Oxygen Levels Cellular Response To Hypoxia Protein Peptidyl-prolyl Isomerization Phosphothreonine Residue Binding Cis-trans Isomerase Activity Supramolecular Fiber Organization Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Regulation Of Actin Filament Polymerization Regulation Of Actin Polymerization Or Depolymerization Positive Regulation Of Gene Expression Regulation Of Actin Filament Length Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress Growth Cone Leading Edge Polysaccharide Digestion Chitin Metabolic Process Endochitinase Activity Chitin Catabolic Process Chitinase Activity Hypoxia-inducible Factor-proline Dioxygenase Activity Peptidyl-proline 4-dioxygenase Activity Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Cellular Response To Oxygen Levels Phosphoserine Residue Binding Positive Regulation Of Translation Histone H3K36me3 Reader Activity Positive Regulation Of Translation In Response To Stress Actin Polymerization-dependent Cell Motility Chitin Binding Signal Complex Assembly
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