RHPN1 and GPRASP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RHPN1	GPRASP2
Description		rhophilin Rho GTPase binding protein 1	G protein-coupled receptor associated sorting protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding	Amyloid-beta Binding G Protein-coupled Receptor Binding Protein Binding
	Biological Process	Signal Transduction Negative Regulation Of Stress Fiber Assembly	Hematopoietic Stem Cell Homeostasis
Pathways		RHO GTPases Activate Rhotekin and Rhophilins RHO GTPases Activate Rhotekin and Rhophilins RHOA GTPase cycle
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: CALCOCO2 CEP70 CNKSR1 EFEMP2 GPRASP2 HAP1 KRT15 KRT31 LZTS1 MTUS2 RHOA ROPN1 TRIM27 TRIM37 TRIM55 TRIM63	52 interacting genes: ADRB1 ARHGEF6 BARD1 CALCR CAVIN3 CBX8 CCDC146 CEP126 CFAP206 CHRM1 CHRM2 DISC1 DSCR9 EFCAB3 FAM124B FCHSD2 FOXD4L1 FRAT1 GADD45GIP1 HAP1 HRH2 HTR7 HTT LRIF1 MBD3L2 MICU2 MYOT NOL4L-DT PIH1D2 PLAC9 PRPF3 PTN RABGEF1 REX1BD RHPN1 RNF8 RPS6KA5 SAPCD2 SEZ6L SH2D4A SREK1 STMN2 TBRG4 TCF25 TSPOAP1 TTC23 TXN TXN2 USP20 ZC2HC1C ZFYVE26 ZNF688
Entrez ID		114822	114928
HPRD ID		17973	06612
Ensembl ID		ENSG00000158106	ENSG00000158301
Uniprot IDs		Q8TCX5	B3KW05 Q96D09
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Microtubule-based Process Supramolecular Fiber Organization Cytoskeleton Myosin Binding Ubiquitin Protein Ligase Activity	G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Trans-synaptic Signaling G Protein-coupled Acetylcholine Receptor Activity Synaptic Signaling Neuromuscular Synaptic Transmission Regulation Of Protein Export From Nucleus Negative Regulation Of Protein Export From Nucleus Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway Microtubule Cytoskeleton Organization Cholinergic Synapse Dendrite
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