RHPN1 and EFEMP2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RHPN1	EFEMP2
Gene Name		rhophilin, Rho GTPase binding protein 1	EGF containing fibulin-like extracellular matrix protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Extracellular Region Basement Membrane Plasma Membrane Vesicle Extracellular Vesicular Exosome
	Molecular Function	Small GTPase Regulator Activity	Transmembrane Signaling Receptor Activity Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding
	Biological Process	Signal Transduction Regulation Of Catalytic Activity	Signal Transduction Blood Coagulation Extracellular Matrix Organization
Pathways			Molecules associated with elastic fibres Elastic fibre formation
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CALCOCO2 CNKSR1 EFEMP2 KRT15 MTUS2 RHOA ROPN1 TRIM27 TRIM37	50 interactors: APEX2 AQP1 ATN1 ATXN1 ATXN7 BAG6 C5orf24 CACNA1A CATSPER1 CCDC33 CCND3 CCNK COL8A1 CREB5 DGCR6 FAM107A FAM124B FAM74A4 GFI1B GLRX3 HDAC4 HHEX HOXA1 IL16 LCE2D LCE3C LINGO1 MEOX2 NEDD4L NOS3 NUFIP2 PIDD1 PLSCR1 PLSCR4 PTGER3 RBPMS RERE RHOXF2 RHPN1 RIBC2 SGTA SGTB STK16 TCAF1 TP53 UBQLN1 UBQLN4 ZNF263 ZNF426 ZNF638
Entrez ID		114822	30008
HPRD ID		17973	05221
Ensembl ID		ENSG00000158106	ENSG00000172638
Uniprot IDs		Q8TCX5	O95967 Q9H3D5
PDB IDs			2KL7
Enriched GO Terms of Interacting Partners?		Rho Protein Signal Transduction Regulation Of Cytoskeleton Organization Negative Regulation Of Interleukin-2 Secretion Histone H2A-K119 Monoubiquitination Skeletal Muscle Satellite Cell Migration Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Centriole Replication Negative Regulation Of Calcium Ion Import Apolipoprotein A-I-mediated Signaling Pathway Ras Protein Signal Transduction Regulation Of Organelle Organization Cleavage Furrow Formation	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Organ Development Response To Salt Stress Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Cell Death Death Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process System Development Developmental Process Phospholipid Scrambling Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Heart Contraction Neuron Death Pons Development Anatomical Structure Development Central Nervous System Development Positive Regulation Of Gene Expression Blood Vessel Development Vasculature Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression
Tagcloud ?			acaa1 analogous ap1m2 aspirates cgn combat dcn ddr1 deadly ec ecs endometrial eps8l2 fastkd1 gmip ikbke minimally noncarcinoma p2rx4 p4hb phkg2 ppfibp2 ppp1r16a rassf7 rnf183 sirt6 socs2 tjp3 uterine
Tagcloud (Difference) ?			acaa1 analogous ap1m2 aspirates cgn combat dcn ddr1 deadly ec ecs endometrial eps8l2 fastkd1 gmip ikbke minimally noncarcinoma p2rx4 p4hb phkg2 ppfibp2 ppp1r16a rassf7 rnf183 sirt6 socs2 tjp3 uterine
Tagcloud (Intersection) ?