PPP1CA and PTEN

  • Number of citations of the paper that reports this interaction (PMID 17274640)
  • 12
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro, in vivo)

PPP1CA

PTEN

Gene Name protein phosphatase 1, catalytic subunit, alpha isozyme phosphatase and tensin homolog
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 148 interactors: AATK AKAP1 AKAP11 AKAP9 AKT1 APAF1 AURKA BAD BAX BCL2 BCL2L1 BCL2L2 BRCA1 BTBD10 C1QA CAD CASC5 CAV1 CCDC181 CD2BP2 CDC5L CDH1 CEP170 CKB CLCN2 CLTC CNP CNST CNTN1 CREB1 CRK CSNK1E CSRNP1 CSRNP2 CUL1 CXXC1 DCTN1 DCX DEAF1 EED EIF2AK2 FRMPD4 FXYD1 GLIPR1L2 GLTSCR2 GPKOW H2AFX HEYL HSPA4 IBTK ID2 JPH3 KANK1 KCNQ1 KCTD20 KIAA1377 KIF13A KIF18A LMTK2 LPIN2 MAFG MAL2 MAP4K4 MAPK1 MAPK3 MIIP MPHOSPH10 MST1R MYO16 NCAM1 NDP NEK2 NOC2L NOM1 NONO PCDH7 PCNA PHACTR1 PHACTR3 PHACTR4 PHC1 PIAS1 PIAS3 PLCL2 POLR2A PPP1R10 PPP1R11 PPP1R13B PPP1R13L PPP1R15A PPP1R15B PPP1R16A PPP1R18 PPP1R1B PPP1R2 PPP1R26 PPP1R2P3 PPP1R2P9 PPP1R32 PPP1R37 PPP1R3B PPP1R3C PPP1R3D PPP1R3E PPP1R3G PPP1R8 PPP1R9A PPP1R9B PPP2CA PREX1 PRKCB PRKCD PRR16 PTEN RANBP9 RB1 RIF1 RPRD2 SFPQ SFRP1 SH3RF2 SKP1 SLC45A1 SNCAIP SORL1 SPRED1 STAM STAU1 SYTL2 TCTEX1D4 TOE1 TOR1AIP1 TOX4 TP53 TP53BP2 TPRN TUSC3 UBE2Z ULK1 VDR WBP11 WDR82 WWTR1 YLPM1 ZBTB11 ZFYVE16 ZFYVE9 ZNF827 34 interactors: AKT1 ANG AR CAV1 CDC27 CHGB COPS6 CSNK2A1 CSNK2A2 DLG1 ESR1 FZR1 HBA1 LATS1 MAGI2 MAGI3 MAST1 MAST2 MAST3 MVP NDFIP1 NEDD4 PARK7 PPP1CA PXN SLC9A3R1 SLC9A3R2 STK11 TP53 UBE2I UBE2L3 USP13 UTP14A WWP1
Entrez ID 5499 5728
HPRD ID 15942 03431
Ensembl ID ENSG00000172531
Uniprot IDs P62136 F6KD01 P60484
PDB IDs 3E7A 3E7B 3EGG 3EGH 3HVQ 3N5U 3V4Y 4G9J 1D5R 2KYL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
0x  1x  adamts13  aspm  atp6v0a2  bioinformatic  bl  chickens  col12a1  fowl  grm5  interpretations  jungle  lrp2  obscn  plau  prkdc  resequencing  rnf168  sanger  sl  slv  smyth  stab2  ubc  ubiquitinylation  vitiliginous  vitiligo  xirp1 
10q  already  ath  aths  atypical  bax  carcinogenesis  ec  ecs  endometrial  frequencies  hyperplasias  igfiir  instability  lead  lesions  lohs  microsatellite  msis  mutated  mutations  pathogenesis  precursor  premalignant  pursue  putative  rii  simple  tgf 
Tagcloud (Difference) ?
0x  1x  adamts13  aspm  atp6v0a2  bioinformatic  bl  chickens  col12a1  fowl  grm5  interpretations  jungle  lrp2  obscn  plau  prkdc  resequencing  rnf168  sanger  sl  slv  smyth  stab2  ubc  ubiquitinylation  vitiliginous  vitiligo  xirp1 
10q  already  ath  aths  atypical  bax  carcinogenesis  ec  ecs  endometrial  frequencies  hyperplasias  igfiir  instability  lead  lesions  lohs  microsatellite  msis  mutated  mutations  pathogenesis  precursor  premalignant  pursue  putative  rii  simple  tgf 
Tagcloud (Intersection) ?