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PPP1CA and PPP1R18
Number of citations of the paper that reports this interaction (PubMedID
17374523
)
0
Data Source:
HPRD
(in vitro, in vivo, two hybrid)
PPP1CA
PPP1R18
Description
protein phosphatase 1 catalytic subunit alpha
protein phosphatase 1 regulatory subunit 18
Image
No pdb structure
GO Annotations
Cellular Component
Protein Phosphatase Type 1 Complex
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Plasma Membrane
Adherens Junction
Glycogen Granule
Neuronal Cell Body
Dendritic Spine
Perikaryon
Extracellular Exosome
PTW/PP1 Phosphatase Complex
Presynapse
Postsynapse
Glutamatergic Synapse
Cytoplasm
Cytoskeleton
Molecular Function
Phosphoprotein Phosphatase Activity
Protein Serine/threonine Phosphatase Activity
Iron Ion Binding
Protein Binding
Protein Phosphatase 1 Binding
Hydrolase Activity
Phosphatase Activity
Ribonucleoprotein Complex Binding
Protein-containing Complex Binding
Metal Ion Binding
Transition Metal Ion Binding
Cadherin Binding Involved In Cell-cell Adhesion
RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity
Actin Binding
Protein Binding
Phosphatase Binding
Biological Process
Telomere Maintenance
RNA Polymerase II Promoter Clearance
Glycogen Metabolic Process
Regulation Of Glycogen Biosynthetic Process
Regulation Of Glycogen Catabolic Process
Transcription By RNA Polymerase II
Transcription Elongation By RNA Polymerase II
Protein Dephosphorylation
Response To Lead Ion
Dephosphorylation
Lung Development
Circadian Regulation Of Gene Expression
Positive Regulation Of Transcription Elongation By RNA Polymerase II
Negative Regulation Of Transcription Elongation By RNA Polymerase II
Regulation Of Circadian Rhythm
Entrainment Of Circadian Clock By Photoperiod
Telomere Maintenance In Response To DNA Damage
Regulation Of Translational Initiation In Response To Stress
Positive Regulation Of Glycogen Biosynthetic Process
Branching Morphogenesis Of An Epithelial Tube
Protein Stabilization
Cell Division
Regulation Of Canonical Wnt Signaling Pathway
Double-strand Break Repair Via Alternative Nonhomologous End Joining
Cell-cell Adhesion
Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Triglyceride catabolism
DARPP-32 events
Downregulation of TGF-beta receptor signaling
Maturation of hRSV A proteins
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
Drugs
2,6,8-Trimethyl-3-Amino-9-Benzyl-9-Methoxynonanoic Acid
Diseases
GWAS
Body fat distribution (arm fat ratio) (
30664634
)
Body fat distribution (leg fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Height (
28552196
)
Autism spectrum disorder or schizophrenia (
28540026
)
Chronic obstructive pulmonary disease (
33909500
)
Hemoglobin levels (
32327693
)
Lung cancer (
28604730
)
Interacting Genes
173 interacting genes:
AATK
AHCTF1
AKAP1
AKAP11
AKAP9
AKT1
APAF1
ASPM
AURKA
BAD
BAX
BCL2
BCL2L1
BCL2L2
BRCA1
BTBD10
C1QA
CAD
CAV1
CCDC181
CDC5L
CDCA2
CDH1
CEP126
CEP170
CEP192
CKB
CLCN2
CLOCK
CNP
CNST
CNTN1
CREB1
CRK
CSNK1E
CSNK2B
CSRNP1
CSRNP2
CUL1
CXXC1
DCTN1
DCX
DEAF1
DELEC1
DYNLT4
EED
EIF2AK2
ESR1
FRMPD4
FXYD1
GLIPR1L2
GPKOW
H2AX
H3-3A
H3C1
HEYL
HSPA4
IBTK
ID2
ITGB8
JPH3
KANK1
KCNQ1
KCTD20
KIF13A
KIF18A
KNL1
LMTK2
LPIN2
MAFG
MAL2
MAP4K4
MAPK1
MAPK3
MAPT
MECOM
MIIP
MKI67
MPHOSPH10
MST1R
MYO16
NCAM1
NDP
NEDD8
NEK2
NOC2L
NOM1
NONO
NOP53
PAK1
PBK
PCDH7
PCNA
PHACTR1
PHACTR3
PHACTR4
PHB2
PHC1
PIAS1
PIAS3
PLCL2
POLR2A
PPP1R10
PPP1R11
PPP1R13B
PPP1R13L
PPP1R15A
PPP1R15B
PPP1R16A
PPP1R18
PPP1R1B
PPP1R2
PPP1R26
PPP1R27
PPP1R2B
PPP1R2C
PPP1R37
PPP1R3B
PPP1R3C
PPP1R3D
PPP1R3E
PPP1R3G
PPP1R8
PPP1R9A
PPP1R9B
PPP2CA
PPP2R5C
PPP2R5E
PREX1
PRKCB
PRKCD
PRR16
PTEN
PTPN7
PYGM
RANBP9
RB1
RORC
RPRD2
RRP1B
SAXO4
SEH1L
SFI1
SFRP1
SH3RF2
SKP1
SLC45A1
SORL1
SPRED1
STAM
STAU1
SYTL2
TOE1
TOR1AIP1
TOX4
TP53
TP53BP2
TPRN
TRIM21
TSC2
TUSC3
UBC
UBE2Z
UBR5
ULK1
VDR
WBP11
WDR82
YLPM1
ZBTB11
ZFYVE16
ZFYVE9
ZNF827
80 interacting genes:
ABRA
ACTN3
BICD2
CALCOCO2
CARD9
CBY2
CCDC102B
CCDC136
CCDC57
CCDC88B
CDR2L
CEP70
COG6
DES
DZIP1
EIF3L
FAM9B
FHL5
FSD2
GCC1
GFAP
GMCL1
GOLGA2
GOLGA6L9
GOPC
GRIPAP1
GTPBP3
HAP1
HOMER3
HOOK2
HSF2BP
IKZF3
KASH5
KCTD9
KRT13
KRT15
KRT16
KRT19
KRT27
KRT31
KRT33B
KRT34
KRT36
KRT40
LDOC1
LZTS1
LZTS2
MAD1L1
MAPK1
MEOX2
MID2
MRPL38
MTUS2
NACA
NEFL
PDE4DIP
PIBF1
PLEKHF2
PPP1CA
PPP1CC
PPP1R13B
PRPH
SORBS3
SPDL1
STX11
TCF4
TEX11
TFIP11
TRAF2
TRIM23
TRIM27
TRIM54
TRIM62
TRIM69
TSC1
TSGA10
VIM
VPS52
ZMYND12
ZRANB1
Entrez ID
5499
170954
HPRD ID
15942
11172
Ensembl ID
ENSG00000172531
ENSG00000146112
Uniprot IDs
A0A140VJS9
P62136
A0A024RCJ8
A0A0G2JHC2
Q6NYC8
PDB IDs
3E7A
3E7B
3EGG
3EGH
3HVQ
3N5U
3V4Y
4G9J
4MOV
4MOY
4MP0
4XPN
5IOH
6ALZ
6CZO
6DCX
6DNO
6G0I
6G0J
6GHM
6OBN
6OBP
6OBQ
6OBR
6OBS
6OBU
6ZEE
6ZEF
6ZEG
6ZEH
6ZEI
6ZEJ
6ZK6
7QFB
7QM2
7T0Y
7TVF
7TXH
7UPI
8DWK
8DWL
8SW5
8SW6
8U5G
Enriched GO Terms of Interacting Partners
?
Protein Phosphatase 1 Binding
Protein Phosphatase Inhibitor Activity
Phosphatase Binding
Intracellular Signal Transduction
Protein Phosphatase Regulator Activity
Protein Phosphatase Type 1 Complex
Negative Regulation Of Intracellular Signal Transduction
Apoptotic Process
Programmed Cell Death
Cell Death
Regulation Of Cell Cycle
Enzyme Binding
Regulation Of Intracellular Signal Transduction
Nucleoplasm
Regulation Of Signal Transduction
Negative Regulation Of Signal Transduction
Regulation Of Cell Communication
Regulation Of Signaling
Intrinsic Apoptotic Signaling Pathway
Nucleus
Glycogen Metabolic Process
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Glycogen Binding
Regulation Of Cell Cycle Process
Positive Regulation Of Macromolecule Metabolic Process
Cellular Response To Stress
Cytoplasm
Positive Regulation Of Metabolic Process
Polysaccharide Metabolic Process
Energy Reserve Metabolic Process
Cell Population Proliferation
Release Of Cytochrome C From Mitochondria
Chromosome
Response To Radiation
Apoptotic Signaling Pathway
Negative Regulation Of Metabolic Process
Regulation Of Protein-containing Complex Assembly
Negative Regulation Of Programmed Cell Death
Response To Starvation
Regulation Of Glycogen Biosynthetic Process
Protein Localization To Organelle
Negative Regulation Of Apoptotic Process
Regulation Of Cell Cycle Phase Transition
Negative Regulation Of Protein Metabolic Process
Signal Transduction
Cellular Response To Oxygen-containing Compound
Response To Light Stimulus
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Bcl-2 Family Protein Complex
Cytoskeleton
Intermediate Filament Organization
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Cytoskeleton Organization
Intermediate Filament
Organelle Organization
Supramolecular Fiber Organization
Structural Constituent Of Skin Epidermis
Keratin Filament
Structural Constituent Of Cytoskeleton
Structural Molecule Activity
Protein Binding
Identical Protein Binding
Intermediate Filament Cytoskeleton
Microtubule-based Process
Centrosome
Morphogenesis Of An Epithelium
Microtubule Cytoskeleton Organization
Tissue Morphogenesis
Cytosol
Cytoplasm
Microtubule Organizing Center
Bergmann Glial Cell Differentiation
Epithelial Cell Differentiation
Microtubule Organizing Center Organization
Negative Regulation Of Viral Transcription
Intracellular Transport
Developmental Process
Regulation Of Viral Transcription
Response To Muramyl Dipeptide
Cellular Developmental Process
Positive Regulation Of Skeletal Muscle Tissue Growth
Establishment Of Localization In Cell
Developmental Process Involved In Reproduction
Establishment Of Protein Localization
Dynein Light Intermediate Chain Binding
Cytoskeleton-dependent Intracellular Transport
Kinetochore Binding
Regulation Of Autophagy
Cell Differentiation
Regulation Of Skeletal Muscle Tissue Growth
Z Disc
Intracellular Protein Localization
Protein Transport
Astrocyte Differentiation
PTW/PP1 Phosphatase Complex
Cellular Localization
Organelle Transport Along Microtubule
Cellular Response To Muramyl Dipeptide
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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