MGLL and CHGB

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MGLL	CHGB
Gene Name		monoglyceride lipase	chromogranin B (secretogranin 1)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Membrane Plasma Membrane Varicosity Synapse	Extracellular Region Secretory Granule
	Molecular Function	Lysophospholipase Activity Lipid Binding Protein Homodimerization Activity Acylglycerol Lipase Activity	Hormone Activity Protein Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Biosynthetic Process Phospholipid Metabolic Process Inflammatory Response Blood Coagulation Regulation Of Signal Transduction Arachidonic Acid Metabolic Process Triglyceride Catabolic Process Platelet Activation Regulation Of Axon Extension Acylglycerol Acyl-chain Remodeling Small Molecule Metabolic Process Acylglycerol Catabolic Process Glycerophospholipid Biosynthetic Process Regulation Of Inflammatory Response Regulation Of Sensory Perception Of Pain Long Term Synaptic Depression Regulation Of Endocannabinoid Signaling Pathway
Pathways		G alpha (q) signalling events Signaling by GPCR Metabolism of lipids and lipoproteins Acyl chain remodeling of DAG and TAG Arachidonate production from DAG Lipid digestion, mobilization, and transport Glycerophospholipid biosynthesis Effects of PIP2 hydrolysis G alpha (q) signalling events GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis Phospholipid metabolism Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: CHGB	31 interactors: ACACA ANXA7 APP ATXN2 CBFB CCDC92 CDKN1A FGFR3 MARK3 MGLL MOGS OGG1 PKN2 POLD1 POLR2E PTEN RAC2 RAP1B RCC1 RXRG S100A8 SAFB2 SGK223 SLC25A6 TAZ TK1 TUBB2A TWF2 UBQLN1 UBTF YLPM1
Entrez ID		11343	1114
HPRD ID		17574	07512
Ensembl ID		ENSG00000074416	ENSG00000089199
Uniprot IDs		B2ZGL7 E7EWX8 Q99685	P05060
PDB IDs		3HJU 3JW8 3JWE 3PE6
Enriched GO Terms of Interacting Partners?			Regulation Of Cellular Component Organization Regulation Of Growth Regulation Of Developmental Growth Cellular Metabolic Process Cellular Component Assembly Regulation Of Mitotic Cell Cycle Regulation Of Metabolic Process Cell Differentiation Regulation Of Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Synaptic Transmission Response To Metal Ion Response To Lipid Regulation Of Gene Expression Cellular Response To Growth Factor Stimulus Regulation Of Cell Development Generation Of Neurons Response To Growth Factor Phosphate-containing Compound Metabolic Process Response To Organic Cyclic Compound Protein Homotetramerization Platelet Activation Positive Regulation Of Metabolic Process Response To Stress Metabolic Process Neurogenesis Response To Organic Substance Positive Regulation Of Lamellipodium Assembly Cellular Process Apoptotic Process Positive Regulation Of Cell Cycle Process Neurotrophin Signaling Pathway Defense Response Hemostasis DNA-templated Transcription, Initiation Negative Regulation Of Developmental Growth Response To Wounding Long Term Synaptic Depression Programmed Cell Death Regulation Of Neurogenesis Nucleotide-excision Repair Positive Regulation Of Lamellipodium Organization Negative Regulation Of Growth Cell Death Death Cell Development Regulation Of Protein Import Into Nucleus, Translocation Developmental Process Regulation Of Cell Morphogenesis Response To Inorganic Substance
Tagcloud ?		acsl3 acyl affymetrix chpt1 cyclotron doxycycline fluidity fourier glycerophospholipid lipg lipid lipids lpe lyso neut npc1 overview peroxidation pg phosphatidylglycerol phospholipid pld1 realtime saturated senescence senescent shortened transform vacuoles	adjunct aggressiveness atrx avidity cc chga chromogranin classifications cytoplasmic daxx exome fdg germline hippel inherited ki lastly lindau neuroendocrine pnet pnets pten retardation rho subcellular tensin thalassemia vhl von
Tagcloud (Difference) ?		acsl3 acyl affymetrix chpt1 cyclotron doxycycline fluidity fourier glycerophospholipid lipg lipid lipids lpe lyso neut npc1 overview peroxidation pg phosphatidylglycerol phospholipid pld1 realtime saturated senescence senescent shortened transform vacuoles	adjunct aggressiveness atrx avidity cc chga chromogranin classifications cytoplasmic daxx exome fdg germline hippel inherited ki lastly lindau neuroendocrine pnet pnets pten retardation rho subcellular tensin thalassemia vhl von
Tagcloud (Intersection) ?