RNF13 and UBE2D4

Number of citations of the paper that reports this interaction (PubMedID 19690564)
61

Data Source:
BioGRID (two hybrid)

		RNF13	UBE2D4
Description		ring finger protein 13	ubiquitin conjugating enzyme E2 D4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Nucleoplasm Cytoplasm Lysosome Lysosomal Membrane Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Late Endosome Membrane	Nucleus
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding JUN Kinase Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Nucleotide Binding Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Transferase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Positive Regulation Of JNK Cascade Organelle Localization Protein Autoubiquitination	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Fish- and plant-related diet ( 32066663) Myocardial infarction ( 26708285)
Interacting Genes		10 interacting genes: LGALS9 SNAPIN TRIM29 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N	111 interacting genes: AMFR ARIH2 ARK2C BFAR BIRC8 CADPS2 CHFR CNOT4 DAZAP2 DTX1 DTX2 DTX3 DTX3L DZIP3 IKBKG INCA1 ITCH LNX1 LRSAM1 MAGEA11 MAP3K1 MARCHF3 MDM2 MGRN1 MIB1 MID1 MID2 MKRN1 MKRN2 MKRN3 MUL1 MYBL2 MYLIP OTUB1 PHF7 PJA2 POLR2E PRKN RBCK1 RBX1 RCHY1 REL RFWD3 RING1 RLIM RMND5B RNF103 RNF11 RNF111 RNF114 RNF115 RNF125 RNF126 RNF13 RNF130 RNF138 RNF14 RNF150 RNF166 RNF167 RNF181 RNF185 RNF2 RNF216 RNF25 RNF26 RNF31 RNF38 RNF4 RNF43 RNF5 RNF7 SIAH1 STUB1 TOPORS TRAF6 TRAF7 TRIM10 TRIM17 TRIM2 TRIM23 TRIM25 TRIM27 TRIM3 TRIM31 TRIM35 TRIM38 TRIM39 TRIM43 TRIM45 TRIM5 TRIM50 TRIM54 TRIM62 TRIM8 UBA1 UBA6 UBC UBE4A UBOX5 UBR5 UBTD1 UBTD2 UFM1 UHRF2 UVSSA WWP2 XIAP ZNRF1 ZNRF2 ZNRF4
Entrez ID		11342	51619
HPRD ID		11503	14242
Ensembl ID		ENSG00000082996	ENSG00000078967
Uniprot IDs		O43567	Q9Y2X8
PDB IDs		5ZBU 5ZC4
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein K48-linked Ubiquitination Ubiquitin-protein Transferase Activity Protein Polyubiquitination Protein Ubiquitination Protein Monoubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Protein K11-linked Ubiquitination ATP Binding Protein K63-linked Ubiquitination Protein Modification Process Macromolecule Catabolic Process Nucleotide Binding Transferase Activity Proteolysis Positive Regulation Of Protein Polyubiquitination Protein Metabolic Process Protein K6-linked Ubiquitination Regulation Of Protein Polyubiquitination Macromolecule Metabolic Process Catabolic Process Positive Regulation Of Activated T Cell Autonomous Cell Death Positive Regulation Of Late Endosome To Lysosome Transport TORC1 Signaling Negative Regulation Of TORC1 Signaling Negative Regulation Of BMP Signaling Pathway Protein Autoubiquitination Positive Regulation Of CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Involved In Immune Response Regulation Of DNA-templated Transcription Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Disaccharide Binding Ubiquitin Protein Ligase Activity TOR Signaling Negative Regulation Of Biosynthetic Process Negative Regulation Of TOR Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Natural Killer Cell Tolerance Induction Regulation Of TORC1 Signaling UBC13-MMS2 Complex Regulation Of RNA Metabolic Process Positive Regulation Of Protein Ubiquitination Ubiquitin Ligase Complex Positive Regulation Of DNA-binding Transcription Factor Activity	Ubiquitin Protein Ligase Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Ubiquitin-protein Transferase Activity Protein Modification Process Zinc Ion Binding Protein Polyubiquitination Transferase Activity Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein Metabolic Process Proteolysis Involved In Protein Catabolic Process Metal Ion Binding Macromolecule Catabolic Process Proteolysis Macromolecule Metabolic Process Catabolic Process Protein Autoubiquitination Protein K48-linked Ubiquitination Proteasomal Protein Catabolic Process Protein K63-linked Ubiquitination Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin Ligase Complex Cytoplasm Ubiquitin-ubiquitin Ligase Activity Innate Immune Response Response To Stress Defense Response To Symbiont Response To Other Organism Defense Response To Other Organism Positive Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Canonical NF-kappaB Signal Transduction Protein K29-linked Ubiquitination Regulation Of Signal Transduction Response To External Biotic Stimulus Immune System Process Defense Response Suppression Of Viral Release By Host Regulation Of Intracellular Signal Transduction Immune Response Protein Monoubiquitination Regulation Of Defense Response Cellular Response To Stress Positive Regulation Of Catabolic Process Positive Regulation Of Signal Transduction Canonical NF-kappaB Signal Transduction Protein Destabilization Host-mediated Suppression Of Symbiont Invasion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?