RNF13

Description		ring finger protein 13
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GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Nucleoplasm Cytoplasm Lysosome Lysosomal Membrane Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Late Endosome Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding JUN Kinase Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Positive Regulation Of JNK Cascade Organelle Localization Protein Autoubiquitination
Pathways
Drugs
Diseases
GWAS		Fish- and plant-related diet ( 32066663) Myocardial infarction ( 26708285)
Novel Interacting Genes		1 novel interacting genes: MLF1
Interacting Genes		10 interacting genes: LGALS9 SNAPIN TRIM29 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N
Entrez ID		11342
HPRD ID		11503
Ensembl ID		ENSG00000082996
Uniprot IDs		O43567
PDB IDs		5ZBU 5ZC4
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein K48-linked Ubiquitination Ubiquitin-protein Transferase Activity Protein Polyubiquitination Protein Ubiquitination Protein Monoubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Protein K11-linked Ubiquitination ATP Binding Protein K63-linked Ubiquitination Protein Modification Process Macromolecule Catabolic Process Nucleotide Binding Transferase Activity Proteolysis Positive Regulation Of Protein Polyubiquitination Protein Metabolic Process Protein K6-linked Ubiquitination Regulation Of Protein Polyubiquitination Macromolecule Metabolic Process Catabolic Process Positive Regulation Of Activated T Cell Autonomous Cell Death Positive Regulation Of Late Endosome To Lysosome Transport TORC1 Signaling Negative Regulation Of TORC1 Signaling Negative Regulation Of BMP Signaling Pathway Protein Autoubiquitination Positive Regulation Of CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Involved In Immune Response Regulation Of DNA-templated Transcription Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Disaccharide Binding Ubiquitin Protein Ligase Activity TOR Signaling Negative Regulation Of Biosynthetic Process Negative Regulation Of TOR Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Natural Killer Cell Tolerance Induction Regulation Of TORC1 Signaling UBC13-MMS2 Complex Regulation Of RNA Metabolic Process Positive Regulation Of Protein Ubiquitination Ubiquitin Ligase Complex Positive Regulation Of DNA-binding Transcription Factor Activity
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