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CHRM4 and GPRASP1
Number of citations of the paper that reports this interaction (PMID
15452121
)
38
Data Source:
HPRD
(in vitro)
CHRM4
GPRASP1
Gene Name
cholinergic receptor, muscarinic 4
G protein-coupled receptor associated sorting protein 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Junction
Postsynaptic Membrane
Cytoplasm
Molecular Function
G-protein Coupled Acetylcholine Receptor Activity
Protein Binding
Biological Process
Signal Transduction
Cell Surface Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G-protein Coupled Acetylcholine Receptor Signaling Pathway
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Cell Proliferation
Regulation Of Locomotion
Endosome To Lysosome Transport
G-protein Coupled Receptor Catabolic Process
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
GPCR downstream signaling
Class A/1 (Rhodopsin-like receptors)
Muscarinic acetylcholine receptors
Amine ligand-binding receptors
G alpha (i) signalling events
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Drugs
Ziprasidone
Amitriptyline
Olanzapine
Metixene
Clozapine
Trihexyphenidyl
Procyclidine
Promazine
Hyoscyamine
Imipramine
Darifenacin
Nortriptyline
Atropine
Nicardipine
Paroxetine
Homatropine Methylbromide
Scopolamine
Benzquinamide
Propiomazine
Cryptenamine
Tropicamide
Brompheniramine
Maprotiline
Tolterodine
Promethazine
Doxepin
Desipramine
Quetiapine
Aripiprazole
Chlorprothixene
Methotrimeprazine
Solifenacin
Isopropamide
Fesoterodine
Aclidinium
Diseases
GWAS
Protein-Protein Interactions
3 interactors:
EEF1A2
GPRASP1
GRB2
47 interactors:
ADRB1
ADRB2
AGTR1
ATXN7
C8orf33
CALCR
CHRM1
CHRM2
CHRM3
CHRM4
CHRM5
CRIP1
CXCR2
F2R
F2RL1
GLP1R
GLYAT
GRM1
GRM5
GRM8
HGH1
HMOX2
HTR7
LAMTOR5
LRP2
MAP7D1
MLNR
MTF2
OFD1
OPRD1
OPRK1
OPRL1
OPRM1
OXTR
PBK
PER1
PFDN1
SNAPIN
STMN2
TAC3
TACR1
TACR2
TACR3
TBXA2R
TFG
TRAF4
VIPR1
Entrez ID
1132
9737
HPRD ID
00330
02333
Ensembl ID
ENSG00000180720
ENSG00000198932
Uniprot IDs
P08173
Q5JY77
PDB IDs
Enriched GO Terms of Interacting Partners
?
Receptor Metabolic Process
G-protein Coupled Receptor Catabolic Process
G-protein Coupled Receptor Signaling Pathway
Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Positive Regulation Of Cytosolic Calcium Ion Concentration
Synaptic Transmission
Cytosolic Calcium Ion Homeostasis
Regulation Of Smooth Muscle Contraction
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway
Cellular Calcium Ion Homeostasis
Calcium Ion Homeostasis
Cellular Response To Stimulus
Cellular Metal Ion Homeostasis
Cell-cell Signaling
Positive Regulation Of Smooth Muscle Contraction
Cellular Cation Homeostasis
Cellular Ion Homeostasis
Signaling
Signal Transduction
Metal Ion Homeostasis
Cell Communication
Blood Circulation
Cellular Chemical Homeostasis
Ion Homeostasis
Response To Stimulus
Neuropeptide Signaling Pathway
Regulation Of Muscle Contraction
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Cellular Homeostasis
Chemical Homeostasis
Regulation Of Blood Pressure
Tachykinin Receptor Signaling Pathway
Regulation Of Systemic Arterial Blood Pressure
Opioid Receptor Signaling Pathway
Regulation Of Vasoconstriction
Positive Regulation Of Uterine Smooth Muscle Contraction
Neurological System Process
Homeostatic Process
Regulation Of Cellular Process
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Blood Pressure
Behavior
Regulation Of CAMP Biosynthetic Process
Sensory Perception Of Pain
Regulation Of Secretion
Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway
Regulation Of CAMP Metabolic Process
Response To Abiotic Stimulus
Regulation Of Adenylate Cyclase Activity
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Tagcloud (Difference)
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Tagcloud (Intersection)
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